Interferon gamma and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni

scientific article published on August 1987

Interferon gamma and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1084/JEM.166.2.589
P932PMC publication ID2189606
P698PubMed publication ID3110355

P2093author name stringKrammer PH
Falk W
Ruppel A
Männel D
Esparza I
P2860cites workTumor necrosis factor: a potent effector molecule for tumor cell killing by activated macrophagesQ35617405
Extracellular cytolysis by activated macrophages and granulocytes. II. Hydrogen peroxide as a mediator of cytotoxicityQ36341041
Purification of cachectin, a lipoprotein lipase-suppressing hormone secreted by endotoxin-induced RAW 264.7 cellsQ36350042
Natural killer (NK) cell-derived hematopoietic colony-inhibiting activity and NK cytotoxic factor. Relationship with tumor necrosis factor and synergism with immune interferonQ36351193
Interrelationships of human interferon-gamma with lymphotoxin and monocyte cytotoxinQ41776641
Tumor necrosis factor and lymphotoxin induce differentiation of human myeloid cell lines in synergy with immune interferonQ41809956
Gamma interferon and lymphotoxin, released by activated T cells, synergize to inhibit granulocyte/monocyte colony formationQ41921376
Lipopolysaccharide-treated RAW 264.7 cells produce a mediator that inhibits lipoprotein lipase in 3T3-L1 cells.Q42816226
Identification and characterization of a human T cell line-derived lymphokine with MAF-like activity distinct from interferon-gamma.Q42819261
Tumor necrosis factor induction by Sendai virusQ43461072
The synergistic anti-proliferative effect of gamma-interferon and human lymphotoxin.Q53550435
Control of cachectin (tumor necrosis factor) synthesis: mechanisms of endotoxin resistance.Q54427953
Macrophage activation to kill Leishmania major: activation of macrophages for intracellular destruction of amastigotes can be induced by both recombinant interferon-gamma and non-interferon lymphokines.Q54790855
Induction of IL 2 receptor expression and cytotoxicity of thymocytes by stimulation with TCF1Q69950597
Priming and triggering of tumoricidal and schistosomulicidal macrophages by two sequential lymphokine signals: interferon-gamma and macrophage cytotoxicity inducing factor 2Q69965055
A lymphokine distinct from interferon-gamma that activates human monocytes to kill Leishmania donovani in vitroQ70276037
Induction of macrophage tumoricidal activity by granulocyte-macrophage colony-stimulating factorQ70282328
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectSchistosoma mansoniQ2324689
P304page(s)589-594
P577publication date1987-08-01
P1433published inJournal of Experimental MedicineQ3186912
P1476titleInterferon gamma and lymphotoxin or tumor necrosis factor act synergistically to induce macrophage killing of tumor cells and schistosomula of Schistosoma mansoni
P478volume166

Reverse relations

cites work (P2860)
Q36987549A role for gamma interferon, tumor necrosis factors, and soluble T-cell receptors in the depressed blastogenic response of spleen cells of Mycobacterium lepraemurium-infected mice
Q68019803A role for protein kinase C in the production of free oxygen radicals in response to Nippostrongylus brasiliensis
Q72531980Acute metabolic effects of human recombinant tumor necrosis factor beta in the rat
Q37185460Adoptive T Cell Therapy of Tumors: Mechanisms Operative in the Recognition and Elimination of Tumor Cells
Q36170491Cell-mediated effector molecules and complicated malaria
Q81637354Characterization of the immunological features of tuberculous pericardial effusions in HIV positive and HIV negative patients in contrast with non-tuberculous effusions
Q55482472Combined antitumor effects of TNF and G-CSF on a human medulloblastoma xenograft line.
Q70526995Correlation between cell-mediated immunity and degree of infection in subjects living in an endemic area of schistosomiasis
Q40427228Cytokine activation of murine macrophages for in vitro killing of Entamoeba histolytica trophozoites
Q42156644Cytokine and eicosanoid regulation by Schistosoma mansoniduring LSE penetration
Q67991377Cytokine interactions in experimental cutaneous leishmaniasis. II. Endogenous tumor necrosis factor-alpha production by macrophages is induced by the synergistic action of interferon (IFN)-gamma and interleukin (IL) 4 and accounts for the antiparasi
Q68094963Differential effects of human blood monocytes on the growth of human tumour cell lines in vitro
Q68105607Effect of interferon-gamma priming on the activation of murine peritoneal macrophages to tumouricidal state by cisplatin, IL-1, and tumour necrosis factor (TNF): production of IL-1 and TNF
Q41595077Effects of recombinant tumour necrosis factor on antibody-dependent eosinophil-mediated damage to Schistosoma japonicum larvae
Q33602505Endogenous gamma interferon is essential in granuloma formation induced by glycolipid-containing mycolic acid in mice
Q36999646Endogenous tumor necrosis factor (cachectin) is essential to host resistance against Listeria monocytogenes infection
Q41631384Enhanced release of prostaglandin E2 from macrophages of rats with silicosis
Q71018519Enhancing effect of oxygen radical scavengers on murine macrophage anticryptococcal activity through production of nitric oxide
Q72965014Entamoeba histolytica proteins modulate the respiratory burst potential by murine macrophages
Q71612610Expression of inducible-NOS in human glomerulonephritis: the possible source is infiltrating monocytes/macrophages
Q36945280Gamma interferon mediates Propionibacterium acnes-induced hypersensitivity to lipopolysaccharide in mice
Q28378560Generation of nitric oxide and induction of major histocompatibility complex class II antigen in macrophages from mice lacking the interferon gamma receptor
Q52481198Granules of human CD3+ large granular lymphocytes contain a macrophage regulating factor(s) that induces macrophage H202 production and tumoricidal activity but decreases cell surface la antigen expression
Q28299701Hemophagocytic syndrome associated with aggressive natural killer cell leukemia
Q35819856Identification of lymphotoxin and tumor necrosis factor in multiple sclerosis lesions
Q40211652Immune reactivity to fractionated Leishmania aethiopica antigens during active human infection
Q33367458Immunological modulation and evasion by helminth parasites in human populations
Q72600523Immunology of leishmaniasis
Q40142324Immunotherapy of airborne tuberculosis in mice via the lung-specific delivery of cytokines
Q36980949In vivo activation of macrophage oxidative burst activity by cytokines and amphotericin B.
Q54703459Indomethacin modulation of monocyte cytokine release following pelvic irradiation for cancer
Q41129871Induction of anti-mycobacterial and anti-listerial activity of human monocytes requires different activation signals
Q35831064Induction of inflammatory cell infiltration and necrosis in normal mouse skin by the combined treatment of tumor necrosis factor and lithium chloride.
Q34747126Inhibition of establishment and growth of mouse liver metastases after treatment with interferon gamma and beta-1,3-D-glucan
Q35105367Inhibition of growth of Chlamydia trachomatis by tumor necrosis factor is accompanied by increased prostaglandin synthesis
Q36798291Inhibition of interferon gamma induced interleukin 12 production: a potential mechanism for the anti-inflammatory activities of tumor necrosis factor
Q37004968Interactions between endogenous gamma interferon and tumor necrosis factor in host resistance against primary and secondary Listeria monocytogenes infections
Q70411572Interferon-gamma and tumor necrosis factor induce the L-arginine-dependent cytotoxic effector mechanism in murine macrophages
Q67987558Killing of Mycobacterium tuberculosis within human monocytes: activation by cytokines and calcitriol
Q36818990LIGHT-related molecular network in the regulation of innate and adaptive immunity
Q30834362Molecular cloning, expression and characterization of ovine TNFα
Q47969127Murine T-cell clones against Entamoeba histolytica: in vivo and in vitro characterization.
Q36663131Nonspecific defence mechanism: the role of nitric oxide
Q43498339Oxygen derived free radicals and the course of Eimeria vermiformis infection in inbred strains of mice
Q35089495Pathogenicity of Mycobacterium avium for human monocytes: absence of macrophage-activating factor activity of gamma interferon
Q68007085Phagocytosis enhances murine macrophage activation by interferon-gamma and tumor necrosis factor-alpha
Q44003358Preactivation of macrophages in mice acutely infected with Schistosoma mansoni
Q36988074Preservation of monocyte effector functions against Mycobacterium avium-M. intracellulare in patients with AIDS.
Q36356489Pretreatment with recombinant murine tumor necrosis factor alpha/cachectin and murine interleukin 1 alpha protects mice from lethal bacterial infection
Q35817197Production of tumor necrosis factor-alpha and lymphotoxin by cells of Hodgkin's neoplastic cell lines HDLM-1 and KM-H2
Q36969949Proliferative responses and gamma interferon and tumor necrosis factor production by lymphocytes isolated from tracheobroncheal lymph nodes and spleen of mice aerosol infected with Bordetella pertussis
Q77882837Protein A of Staphylococcus aureus evokes Th1 type response in mice
Q68418335Regulation of macrophage-mediated larvicidal activity in Echinococcus granulosus and Mesocestoides corti (Cestoda) infection in mice
Q40724076Role of cytokines in tuberculosis
Q36670368Role of nitric oxide in parasitic infections
Q36656920Role of nitric oxide synthesis in macrophage antimicrobial activity
Q35512225Roles for tumor necrosis factor alpha and nitric oxide in resistance of rat alveolar macrophages to Legionella pneumophila
Q35090879Separate and combined effects of recombinant interleukin-1 alpha and gamma interferon on antibacterial resistance
Q41641701Synergism between tumor necrosis factor-alpha and interferon-gamma on macrophage activation for the killing of intracellular Trypanosoma cruzi through a nitric oxide-dependent mechanism
Q67601036The effects of tumour necrosis factor on host-parasite relations in murine Mesocestoides corti (Cestoda) infection
Q34768645The immune response to Plasmodium falciparum malaria.
Q39608679The role of T cell--macrophage interactions in tuberculosis
Q38669947The role of free oxygen radicals in the expulsion of primary infections of Nippostrongylus brasiliensis
Q44609581The schistosomulicidal activity and the production of IL-1 and TNF-alpha by peritoneal macrophages from infected mice and their potentiation by muramyl tripeptide-phosphatidyl ethanolamine (MTP-PE) treatment
Q44879905Tumor necrosis factor-alpha in combination with interferon-gamma, but not with interleukin 4 activates murine macrophages for elimination of Leishmania major amastigotes
Q55148781Tumor-specific T cells which form clusters with dendritic cells and tumor cells and deliver macrophage-activating factors.
Q44480969Tumour necrosis factor (TNF) as a mediator of macrophage helminthotoxic activity
Q40644530Tumour necrosis factor and associated cytokines in the host's response to malaria
Q79316072Up-regulation of granulomatous inflammation in interleukin-6 knockout mice infected with Rhodococcus aurantiacus

Search more.