Depletion of ascorbic acid restricts angiogenesis and retards tumor growth in a mouse model

scientific article published on January 2007

Depletion of ascorbic acid restricts angiogenesis and retards tumor growth in a mouse model is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1593/NEO.06664
P932PMC publication ID1804324
P698PubMed publication ID17325743
P5875ResearchGate publication ID6480247

P2093author name stringJohn W Eaton
Amy L Clem
Jason Chesney
Sucheta Telang
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Quantitative determination of water- and lipid-soluble antioxidants in neoplastic and non-neoplastic human breast tissueQ69628297
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Ascorbic acid inhibits apoptosis induced by X irradiation in HL60 myeloid leukemia cellsQ73084274
Increased facilitated transport of dehydroascorbic acid without changes in sodium-dependent ascorbate transport in human melanoma cellsQ73436995
Type IV collagen modulates angiogenesis and neovessel survival in the rat aorta modelQ74151898
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Ascorbic acid is a potent inhibitor of various forms of T cell apoptosisQ77840725
Vitamin C deficiency in guinea pigs differentially affects the expression of type IV collagen, laminin, and elastin in blood vesselsQ77897069
Vitamin C in human health and disease is still a mystery? An overviewQ21245913
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Antibody against junctional adhesion molecule-C inhibits angiogenesis and tumor growthQ24306682
Supplemental ascorbate in the supportive treatment of cancer: Prolongation of survival times in terminal human cancerQ24561618
Supplemental ascorbate in the supportive treatment of cancer: Reevaluation of prolongation of survival times in terminal human cancerQ24616530
Aortic wall damage in mice unable to synthesize ascorbic acidQ24678375
Tumor angiogenesis: therapeutic implicationsQ27860595
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The biology of vascular endothelial growth factorQ29615946
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High-dose vitamin C versus placebo in the treatment of patients with advanced cancer who have had no prior chemotherapy. A randomized double-blind comparisonQ34193191
Synthesis of Antihemophilic Factor Antigen by Cultured Human Endothelial CellsQ34513117
Tumor dormancy in vivo by prevention of neovascularizationQ36271710
Quantitative immunohistochemistry by measuring cumulative signal strength accurately measures receptor numberQ38453786
Quantitative immunohistochemistry by measuring cumulative signal strength using commercially available software photoshop and matlabQ39526964
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Vitamin C inhibits FAS-induced apoptosis in monocytes and U937 cellsQ40665840
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Glioblastoma growth inhibited in vivo by a dominant-negative Flk-1 mutantQ41488146
1 Selected methods for the determination of ascorbic acid in animal cells, tissues, and fluidsQ41580568
Effect of ascorbic acid on tumour growthQ42578558
Reevaluation of ascorbate in cancer treatment: emerging evidence, open minds and serendipityQ42632623
Ascorbic acid and N-acetylcysteine improve in vitro the function of lymphocytes from mice with endotoxin-induced oxidative stress.Q43791121
The antifungal drug ciclopirox inhibits deoxyhypusine and proline hydroxylation, endothelial cell growth and angiogenesis in vitroQ44062533
Ascorbic acid-independent synthesis of collagen in miceQ46472587
Mammalian facilitative hexose transporters mediate the transport of dehydroascorbic acidQ49140908
A specific decrease in collagen synthesis in acutely fasted, vitamin C-supplemented, guinea pigs.Q51638489
Use of nude mouse xenografts as preclinical drug screens: in vivo activity of established chemotherapeutic agents against melanoma and ovarian carcinoma xenografts.Q52601932
Inhibition of angiogenesis through modulation of collagen metabolism.Q64957555
von Willebrand factorQ67765089
P433issue1
P304page(s)47-56
P577publication date2007-01-01
P1433published inNeoplasiaQ2962042
P1476titleDepletion of ascorbic acid restricts angiogenesis and retards tumor growth in a mouse model
P478volume9

Reverse relations

cites work (P2860)
Q43055596Anti-angiogenic effect of high doses of ascorbic acid
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Q34336161Current limitations of murine models in oncology for ascorbate research
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Q35199928Differential gene expression between wild-type and Gulo-deficient mice supplied with vitamin C.
Q34263572Does vitamin C deficiency affect cognitive development and function?
Q36084737Effects of ascorbic acid on carcinogenicity and acute toxicity of nickel subsulfide, and on tumor transplants growth in gulonolactone oxidase knock-out mice and wild-type C57BL mice
Q39699715Endothelial cells regulate cardiomyocyte development from embryonic stem cells
Q53117821Histological evaluation of the periodontal ligament from aged Wistar rats supplemented with ascorbic acid.
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