scholarly article | Q13442814 |
P356 | DOI | 10.1016/J.CUB.2012.03.051 |
P8608 | Fatcat ID | release_bjmcd3ph75hqplc6sjhe5gfc3i |
P932 | PMC publication ID | 3780767 |
P698 | PubMed publication ID | 22521786 |
P5875 | ResearchGate publication ID | 224810325 |
P50 | author | Kevin G Hardwick | Q42870286 |
Jonathan B Millar | Q63384820 | ||
Juan Zou | Q79743363 | ||
Lindsey A Shepperd | Q114783653 | ||
Alicja Sochaj-Grzegorczyk | Q114783654 | ||
Graham J Buttrick | Q114783655 | ||
Juri Rappsilber | Q28324182 | ||
P2093 | author name string | John C Meadows | |
Theresa C Lancaster | |||
P2860 | cites work | Human Blinkin/AF15q14 is required for chromosome alignment and the mitotic checkpoint through direct interaction with Bub1 and BubR1 | Q24299555 |
A conserved protein network controls assembly of the outer kinetochore and its ability to sustain tension | Q24304199 | ||
Structural analysis reveals features of the spindle checkpoint kinase Bub1-kinetochore subunit Knl1 interaction | Q24305233 | ||
The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase | Q24314385 | ||
Molecular analysis of kinetochore architecture in fission yeast | Q24535584 | ||
A quantitative atlas of mitotic phosphorylation | Q24646817 | ||
Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores | Q24682946 | ||
The Schizosaccharomyces pombe spindle checkpoint protein mad2p blocks anaphase and genetically interacts with the anaphase-promoting complex | Q24683919 | ||
Structural basis for phosphodependent substrate selection and orientation by the SCFCdc4 ubiquitin ligase | Q27640370 | ||
Bub3p facilitates spindle checkpoint silencing in fission yeast | Q42953648 | ||
A novel protein phosphatase 1-dependent spindle checkpoint silencing mechanism | Q42956392 | ||
The fission yeast dis2+ gene required for chromosome disjoining encodes one of two putative type 1 protein phosphatases. | Q44879911 | ||
Mph1, a member of the Mps1-like family of dual specificity protein kinases, is required for the spindle checkpoint in S. pombe. | Q48037929 | ||
p93dis1, which is required for sister chromatid separation, is a novel microtubule and spindle pole body-associating protein phosphorylated at the Cdc2 target sites | Q48072526 | ||
The NDA3 gene of fission yeast encodes β-tubulin: A cold-sensitive nda3 mutation reversibly blocks spindle formation and chromosome movement in mitosis | Q48385612 | ||
Kinesins klp5(+) and klp6(+) are required for normal chromosome movement in mitosis. | Q52123192 | ||
The fission yeast DASH complex is essential for satisfying the spindle assembly checkpoint induced by defects in the inner-kinetochore proteins | Q79921719 | ||
Structure of a Blinkin-BUBR1 Complex Reveals an Interaction Crucial for Kinetochore-Mitotic Checkpoint Regulation via an Unanticipated Binding Site | Q27675055 | ||
The spindle-assembly checkpoint in space and time | Q27860766 | ||
Activation of the budding yeast spindle assembly checkpoint without mitotic spindle disruption. | Q27933791 | ||
Budding yeast Cdc20: a target of the spindle checkpoint. | Q27936296 | ||
Role of Hec1 in spindle checkpoint signaling and kinetochore recruitment of Mad1/Mad2 | Q28204299 | ||
Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores | Q28290993 | ||
Crystal structure of the spindle assembly checkpoint protein Bub3 | Q28293385 | ||
Nsk1 ensures accurate chromosome segregation by promoting association of kinetochores to spindle poles during anaphase B | Q28742174 | ||
Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage | Q29618221 | ||
A 20S complex containing CDC27 and CDC16 catalyzes the mitosis-specific conjugation of ubiquitin to cyclin B | Q29620071 | ||
Kinetochore localization of spindle checkpoint proteins: who controls whom? | Q30448761 | ||
The DASH complex and Klp5/Klp6 kinesin coordinate bipolar chromosome attachment in fission yeast | Q30476087 | ||
Bub1 and Bub3 promote the conversion from monopolar to bipolar chromosome attachment independently of shugoshin | Q30489580 | ||
KNL1/Spc105 recruits PP1 to silence the spindle assembly checkpoint | Q30500882 | ||
Regulated targeting of protein phosphatase 1 to the outer kinetochore by KNL1 opposes Aurora B kinase | Q33751737 | ||
Mps1 directs the assembly of Cdc20 inhibitory complexes during interphase and mitosis to control M phase timing and spindle checkpoint signaling. | Q34026709 | ||
Cut2 proteolysis required for sister-chromatid seperation in fission yeast | Q34733084 | ||
Centromere-tethered Mps1 pombe homolog (Mph1) kinase is a sufficient marker for recruitment of the spindle checkpoint protein Bub1, but not Mad1. | Q35657719 | ||
Cdk1 phosphorylation of the kinetochore protein Nsk1 prevents error-prone chromosome segregation | Q35670629 | ||
Microtubule binding by KNL-1 contributes to spindle checkpoint silencing at the kinetochore | Q35770562 | ||
Fission yeast bub1 is a mitotic centromere protein essential for the spindle checkpoint and the preservation of correct ploidy through mitosis | Q36328520 | ||
Schizosaccharomyces pombe Bub3 is dispensable for mitotic arrest following perturbed spindle formation | Q36724332 | ||
Kinetochore stretching inactivates the spindle assembly checkpoint | Q37106715 | ||
Intrakinetochore stretch is associated with changes in kinetochore phosphorylation and spindle assembly checkpoint activity | Q37106724 | ||
Kinetochore targeting of fission yeast Mad and Bub proteins is essential for spindle checkpoint function but not for all chromosome segregation roles of Bub1p | Q37598776 | ||
Spindle-kinetochore attachment requires the combined action of Kin I-like Klp5/6 and Alp14/Dis1-MAPs in fission yeast | Q39687466 | ||
Systematic phosphorylation analysis of human mitotic protein complexes. | Q41789354 | ||
Spindle checkpoint silencing requires association of PP1 to both Spc7 and kinesin-8 motors. | Q41867463 | ||
Aurora controls sister kinetochore mono-orientation and homolog bi-orientation in meiosis-I. | Q42023656 | ||
Kinase activity of fission yeast Mph1 is required for Mad2 and Mad3 to stably bind the anaphase promoting complex | Q42116229 | ||
Protein interaction domain mapping of human kinetochore protein Blinkin reveals a consensus motif for binding of spindle assembly checkpoint proteins Bub1 and BubR1 | Q42707082 | ||
P433 | issue | 10 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Bub1-Bub3 complex localization to kinetochore | Q22290911 |
bub1-bub3 complex | Q22328438 | ||
P304 | page(s) | 891-899 | |
P577 | publication date | 2012-04-19 | |
P1433 | published in | Current Biology | Q1144851 |
P1476 | title | Phosphodependent recruitment of Bub1 and Bub3 to Spc7/KNL1 by Mph1 kinase maintains the spindle checkpoint | |
P478 | volume | 22 |
Q37614863 | A Bub1-Mad1 interaction targets the Mad1-Mad2 complex to unattached kinetochores to initiate the spindle checkpoint |
Q28075699 | A Cell Biological Perspective on Past, Present and Future Investigations of the Spindle Assembly Checkpoint |
Q30277861 | A Centromere-Signaling Network Underlies the Coordination among Mitotic Events |
Q53097004 | A Kinase-Phosphatase Network that Regulates Kinetochore-Microtubule Attachments and the SAC. |
Q34062544 | A cooperative mechanism drives budding yeast kinetochore assembly downstream of CENP-A. |
Q88143935 | A kinetochore-based ATM/ATR-independent DNA damage checkpoint maintains genomic integrity in trypanosomes. |
Q36674339 | A knockout screen for protein kinases required for the proper meiotic segregation of chromosomes in the fission yeast Schizosaccharomyces pombe. |
Q24322740 | A microtubule-associated zinc finger protein, BuGZ, regulates mitotic chromosome alignment by ensuring Bub3 stability and kinetochore targeting |
Q41544497 | A molecular basis for the differential roles of Bub1 and BubR1 in the spindle assembly checkpoint |
Q35560978 | A motif from Lys216 to Lys222 in human BUB3 protein is a nuclear localization signal and critical for BUB3 function in mitotic checkpoint |
Q42327875 | A sequential multi-target Mps1 phosphorylation cascade promotes spindle checkpoint signaling |
Q24300982 | A small-molecule inhibitor of Haspin alters the kinetochore functions of Aurora B |
Q36561533 | ASPP1/2-PP1 complexes are required for chromosome segregation and kinetochore-microtubule attachments |
Q41880466 | All together now: Polo joins the kinase network controlling the spindle assembly checkpoint in Drosophila. |
Q37411035 | Arrayed BUB recruitment modules in the kinetochore scaffold KNL1 promote accurate chromosome segregation |
Q90317138 | Aurora B kinase activity-dependent and -independent functions of the chromosomal passenger complex in regulating sister chromatid cohesion |
Q89577893 | Aurora B kinase is recruited to multiple discrete kinetochore and centromere regions in human cells |
Q34407585 | Bimodal activation of BubR1 by Bub3 sustains mitotic checkpoint signaling |
Q39480463 | Borealin dimerization mediates optimal CPC checkpoint function by enhancing localization to centromeres and kinetochores |
Q30667283 | Bub1 autophosphorylation feeds back to regulate kinetochore docking and promote localized substrate phosphorylation |
Q41969716 | Bub1 positions Mad1 close to KNL1 MELT repeats to promote checkpoint signalling |
Q27310404 | Bub3 promotes Cdc20-dependent activation of the APC/C in S. cerevisiae |
Q27680055 | Bub3 reads phosphorylated MELT repeats to promote spindle assembly checkpoint signaling |
Q27309441 | Bub3-BubR1-dependent sequestration of Cdc20Fizzy at DNA breaks facilitates the correct segregation of broken chromosomes |
Q42377059 | BubR1 Promotes Bub3-Dependent APC/C Inhibition during Spindle Assembly Checkpoint Signaling. |
Q64295741 | CDK1-CCNB1 creates a spindle checkpoint-permissive state by enabling MPS1 kinetochore localization |
Q40841925 | CELL DIVISION CYCLE. Kinetochore attachment sensed by competitive Mps1 and microtubule binding to Ndc80C. |
Q30409397 | CENP-I and Aurora B act as a molecular switch that ties RZZ/Mad1 recruitment to kinetochore attachment status. |
Q26998631 | Cell division: control of the chromosomal passenger complex in time and space |
Q42044396 | Checkpoint proteins come under scrutiny |
Q38176326 | Chromosome segregation in budding yeast: sister chromatid cohesion and related mechanisms. |
Q89565601 | Connecting GCN5's centromeric SAGA to the mitotic tension-sensing checkpoint |
Q30300041 | Connecting the microtubule attachment status of each kinetochore to cell cycle arrest through the spindle assembly checkpoint |
Q38025305 | Connecting up and clearing out: how kinetochore attachment silences the spindle assembly checkpoint. |
Q90583661 | Cyclin B1 scaffolds MAD1 at the kinetochore corona to activate the mitotic checkpoint |
Q35610725 | DNA damage response and spindle assembly checkpoint function throughout the cell cycle to ensure genomic integrity |
Q40459343 | Dissecting the first and the second meiotic divisions using a marker-less drug-hypersensitive fission yeast. |
Q47741337 | Distinct Roles of the Chromosomal Passenger Complex in the Detection of and Response to Errors in Kinetochore-Microtubule Attachment. |
Q30653598 | Distinct domains in Bub1 localize RZZ and BubR1 to kinetochores to regulate the checkpoint |
Q64067273 | Division of labour between PP2A-B56 isoforms at the centromere and kinetochore |
Q50532403 | Drosophila Nnf1 paralogs are partially redundant for somatic and germ line kinetochore function. |
Q30540597 | Drosophila Polo regulates the spindle assembly checkpoint through Mps1-dependent BubR1 phosphorylation |
Q38711755 | Dual recognition of chromatin and microtubules by INCENP is important for mitotic progression. |
Q34263732 | Dynamic autophosphorylation of mps1 kinase is required for faithful mitotic progression |
Q35989892 | Dynamic localization of Mps1 kinase to kinetochores is essential for accurate spindle microtubule attachment |
Q91964062 | Effect of KNL1 on the proliferation and apoptosis of colorectal cancer cells |
Q91726226 | Efficient mitotic checkpoint signaling depends on integrated activities of Bub1 and the RZZ complex |
Q90131687 | Enrichment of Aurora B kinase at the inner kinetochore controls outer kinetochore assembly |
Q94458549 | Ensemble-Level Organization of Human Kinetochores and Evidence for Distinct Tension and Attachment Sensors |
Q38782316 | Functional and Structural Characterization of Bub3·BubR1 Interactions Required for Spindle Assembly Checkpoint Signaling in Human Cells. |
Q33751085 | Gene and miRNA expression profiles of mouse Lewis lung carcinoma LLC1 cells following single or fractionated dose irradiation. |
Q41295600 | Generation of a Spindle Checkpoint Arrest from Synthetic Signaling Assemblies |
Q40856838 | Getting to the heart of an unusual kinetochore |
Q47921014 | How Kinetochore Architecture Shapes the Mechanisms of Its Function |
Q40148229 | Identifying novel protein phenotype annotations by hybridizing protein-protein interactions and protein sequence similarities. |
Q36000719 | Ipl1/Aurora-B is necessary for kinetochore restructuring in meiosis I in Saccharomyces cerevisiae |
Q37411020 | KNL1 facilitates phosphorylation of outer kinetochore proteins by promoting Aurora B kinase activity |
Q27001042 | KNL1: bringing order to the kinetochore |
Q55512020 | Kinase and Phosphatase Cross-Talk at the Kinetochore. |
Q39277531 | Kinetochore KMN network gene CASC5 mutated in primary microcephaly |
Q27309180 | Kinetochore function is controlled by a phospho-dependent coexpansion of inner and outer components |
Q35642690 | Kinetochore-localized BUB-1/BUB-3 complex promotes anaphase onset in C. elegans |
Q51766232 | Lateral attachment of kinetochores to microtubules is enriched in prometaphase rosette and facilitates chromosome alignment and bi-orientation establishment. |
Q30841621 | Loss of Centromere Cohesion in Aneuploid Human Oocytes Correlates with Decreased Kinetochore Localization of the Sac Proteins Bub1 and Bubr1 |
Q55308042 | MAD1: Kinetochore Receptors and Catalytic Mechanisms. |
Q42152374 | MPS1/Mph1 phosphorylates the kinetochore protein KNL1/Spc7 to recruit SAC components |
Q27930798 | Mad1 kinetochore recruitment by Mps1-mediated phosphorylation of Bub1 signals the spindle checkpoint. |
Q36879638 | Making an effective switch at the kinetochore by phosphorylation and dephosphorylation |
Q61449465 | Mapping Mitotic Death: Functional Integration of Mitochondria, Spindle Assembly Checkpoint and Apoptosis |
Q47158873 | Mechanistic insight into TRIP13-catalyzed Mad2 structural transition and spindle checkpoint silencing |
Q38069082 | Microtubule attachment and spindle assembly checkpoint signalling at the kinetochore |
Q89673525 | Mitotic kinase anchoring proteins: the navigators of cell division |
Q46889398 | Molecular Mechanisms of Spindle Assembly Checkpoint Activation and Silencing |
Q38835748 | Molecular basis underlying resistance to Mps1/TTK inhibitors. |
Q34979651 | Molecular pathways: regulation and targeting of kinetochore-microtubule attachment in cancer |
Q52368035 | Mps1 Phosphorylates Its N-Terminal Extension to Relieve Autoinhibition and Activate the Spindle Assembly Checkpoint. |
Q48610746 | Mps1 Regulates Kinetochore-Microtubule Attachment Stability via the Ska Complex to Ensure Error-Free Chromosome Segregation |
Q33797037 | Mps1 phosphorylation of condensin II controls chromosome condensation at the onset of mitosis |
Q91747570 | Mps1 regulates spindle morphology through MCRS1 to promote chromosome alignment |
Q35925170 | Mps1Mph1 Kinase Phosphorylates Mad3 to Inhibit Cdc20Slp1-APC/C and Maintain Spindle Checkpoint Arrests |
Q48503928 | Multiple Duties for Spindle Assembly Checkpoint Kinases in Meiosis. |
Q41784331 | Multiple assembly mechanisms anchor the KMN spindle checkpoint platform at human mitotic kinetochores |
Q49848965 | Multitasking Ska in Chromosome Segregation: Its Distinct Pools Might Specify Various Functions |
Q41946221 | Natural Loss of Mps1 Kinase in Nematodes Uncovers a Role for Polo-like Kinase 1 in Spindle Checkpoint Initiation. |
Q38939972 | Negative feedback at kinetochores underlies a responsive spindle checkpoint signal. |
Q27310281 | Nup132 modulates meiotic spindle attachment in fission yeast by regulating kinetochore assembly |
Q33987594 | Optimization of the analogue-sensitive Cdc2/Cdk1 mutant by in vivo selection eliminates physiological limitations to its use in cell cycle analysis |
Q37638990 | PKM2 regulates chromosome segregation and mitosis progression of tumor cells. |
Q92751182 | PP1 and PP2A Use Opposite Phospho-dependencies to Control Distinct Processes at the Kinetochore |
Q41956782 | PP2A-B56 opposes Mps1 phosphorylation of Knl1 and thereby promotes spindle assembly checkpoint silencing |
Q64245408 | Phosphatases in Mitosis: Roles and Regulation |
Q39258525 | Playing polo during mitosis: PLK1 takes the lead. |
Q41459053 | Plk1 bound to Bub1 contributes to spindle assembly checkpoint activity during mitosis. |
Q39045643 | Premature Silencing of the Spindle Assembly Checkpoint Is Prevented by the Bub1-H2A-Sgo1-PP2A Axis in Saccharomyces cerevisiae |
Q36624591 | Probing the catalytic functions of Bub1 kinase using the small molecule inhibitors BAY-320 and BAY-524. |
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Q42262874 | Protein Phosphatase 1 inactivates Mps1 to ensure efficient Spindle Assembly Checkpoint silencing. |
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Q89667135 | Recent advances in understanding the role of Cdk1 in the Spindle Assembly Checkpoint |
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Q38866759 | Regulation of mitotic progression by the spindle assembly checkpoint |
Q35866864 | Role of Intrinsic and Extrinsic Factors in the Regulation of the Mitotic Checkpoint Kinase Bub1. |
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Q38331468 | Sharpening the anaphase switch. |
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Q47741955 | Stability of kinetochore-microtubule attachment and the role of different KMN network components in Drosophila |
Q27682810 | Structural and functional insights into the role of the N-terminal Mps1 TPR domain in the SAC (spindle assembly checkpoint) |
Q39696988 | Synthetic Physical Interactions Map Kinetochore-Checkpoint Activation Regions. |
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Q41839674 | Widespread Recurrent Patterns of Rapid Repeat Evolution in the Kinetochore Scaffold KNL1. |
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