Interferon alpha-2b inhibits negative-strand RNA and protein expression from full-length HCV1a infectious clone

scientific article published on June 2004

Interferon alpha-2b inhibits negative-strand RNA and protein expression from full-length HCV1a infectious clone is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEXMP.2004.01.004
P698PubMed publication ID15126107

P50authorRobert F. GarryQ66732989
M Ramesh PrabhuQ91976469
Srikanta DashQ96901165
Virendra JoshiQ114293693
Salima HaqueQ114734964
Fredric G RegensteinQ114734966
Swan N ThungQ114734967
P2093author name stringFrank Bastian
P2860cites workInterferon-alpha inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathwayQ43030367
Inducible model to study negative strand RNA synthesis and assembly of hepatitis C virus from a full-length cDNA cloneQ43031268
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Cultivation of hepatitis C virus in primary hepatocyte culture from patients with chronic hepatitis C results in release of high titre infectious virusQ43046665
Hepatitis C viral proteins affect cell viability and membrane permeability.Q50502497
Infectious defective interfering particles of VSV from transcripts of a cDNA cloneQ67490017
3' nontranslated RNA signals required for replication of hepatitis C virus RNAQ24550606
A recombinant hepatitis C virus RNA-dependent RNA polymerase capable of copying the full-length viral RNA.Q27469369
Hepatitis C virus-encoded enzymatic activities and conserved RNA elements in the 3' nontranslated region are essential for virus replication in vivoQ27469634
Effect of alpha interferon on the hepatitis C virus repliconQ27469963
Sequences in the 5' nontranslated region of hepatitis C virus required for RNA replication.Q27469999
Genetic Analysis of Sequences in the 3' Nontranslated Region of Hepatitis C Virus That Are Important for RNA ReplicationQ27472973
Efficient Replication of Hepatitis C Virus Genotype 1a RNAs in Cell CultureQ27473339
Identification of a highly conserved sequence element at the 3' terminus of hepatitis C virus genome RNAQ27480384
Transcripts from a single full-length cDNA clone of hepatitis C virus are infectious when directly transfected into the liver of a chimpanzeeQ27485872
Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C terminiQ27485927
Internal ribosome entry site within hepatitis C virus RNAQ27486220
In vivo analysis of the 3' untranslated region of the hepatitis C virus after in vitro mutagenesis of an infectious cDNA cloneQ27488360
Transmission of hepatitis C by intrahepatic inoculation with transcribed RNAQ27860484
Efficient initiation of HCV RNA replication in cell cultureQ27860520
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Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysisQ27860603
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genomeQ27860719
Interferons: cell signalling, immune modulation, antiviral response and virus countermeasuresQ29618978
Secondary structure of the 5' nontranslated regions of hepatitis C virus and pestivirus genomic RNAsQ29619052
Hepatitis C virus shares amino acid sequence similarity with pestiviruses and flaviviruses as well as members of two plant virus supergroupsQ29620772
Sequence analysis of the 5' noncoding region of hepatitis C virusQ29620975
Hepatitis C virus replication is directly inhibited by IFN-alpha in a full-length binary expression systemQ33934023
Inhibition of the cellular response to interferons by products of the adenovirus type 5 E1A oncogeneQ35776542
Correlation between the infectivity of hepatitis C virus in vivo and its infectivity in vitroQ36390620
Adenovirus early region 1A modulation of interferon antiviral activityQ36885532
Evidence for in vitro replication of hepatitis C virus genome in a human T-cell lineQ37061606
Repression of the interferon signal transduction pathway by the adenovirus E1A oncogeneQ37590901
Specific inhibition of interferon signal transduction pathways by adenoviral infectionQ40773522
A human liver cell line exhibits efficient translation of HCV RNAs produced by a recombinant adenovirus expressing T7 RNA polymeraseQ41003000
Long-term human T-cell culture system supporting hepatitis C virus replicationQ41157566
Hepatitis C virus: detection of intracellular virus particles by electron microscopyQ41235560
Susceptibility of human T-lymphotropic virus type I infected cell line MT-2 to hepatitis C virus infectionQ41379146
The molecular virology of hepatitis C.Q41499865
The human bone-marrow-derived B-cell line CE, susceptible to hepatitis C virus infection.Q41545820
Transcripts of a chimeric cDNA clone of hepatitis C virus genotype 1b are infectious in vivo.Q42677425
HCV RNA levels in hepatocellular carcinomas and adjacent non-tumorous liversQ43000351
P433issue3
P304page(s)242-252
P577publication date2004-06-01
P1433published inExperimental and Molecular PathologyQ15767470
P1476titleInterferon alpha-2b inhibits negative-strand RNA and protein expression from full-length HCV1a infectious clone
P478volume76

Reverse relations

cites work (P2860)
Q40409455Activation of interferon-stimulated response element in huh-7 cells replicating hepatitis C virus subgenomic RNA.
Q40361695Alpha interferon inhibits translation mediated by the internal ribosome entry site of six different hepatitis C virus genotypes
Q39813695An Assessment of the Use of Chimpanzees in Hepatitis C Research Past, Present and Future: 1. Validity of the Chimpanzee Model
Q33908879Antiviral potency analysis and functional comparison of consensus interferon, interferon-alpha2a and pegylated interferon-alpha2b against hepatitis C virus infection.
Q29618976Evasion of intracellular host defence by hepatitis C virus
Q34235286Hepatitis C virus experimental model systems and antiviral drug research
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Q36703045In vitro replication models for the hepatitis C virus
Q27477552Inhibition of Hepatitis C Virus Nonstructural Protein, Helicase Activity, and Viral Replication by a Recombinant Human Antibody Clone
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Q27477778Small interfering RNA targeted to stem-loop II of the 5' untranslated region effectively inhibits expression of six HCV genotypes