Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts

scientific article published in April 2000

Apoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1042/0264-6021:3470543
P932PMC publication ID1220988
P698PubMed publication ID10749685
P5875ResearchGate publication ID12566058

P2093author name stringLiu J
Chen QM
Merrett JB
P2860cites workBcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell deathQ24312211
A model for p53-induced apoptosisQ24313374
Inhibition of Bax channel-forming activity by Bcl-2Q24317099
Prevention of apoptosis by Bcl-2: release of cytochrome c from mitochondria blockedQ24318845
Caspases: the executioners of apoptosisQ24530218
Oxidants, antioxidants, and the degenerative diseases of agingQ24561734
A biomarker that identifies senescent human cells in culture and in aging skin in vivoQ24562644
Cells in stress: transcriptional activation of heat shock genesQ28267155
Bax in murine thymus is a soluble monomeric protein that displays differential detergent-induced conformationsQ28506809
Bax directly induces release of cytochrome c from isolated mitochondriaQ28588847
Apoptosis: molecular regulation of cell deathQ28611445
Caspases: enemies withinQ29547315
The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosisQ29616513
The Bcl-2 protein family: arbiters of cell survivalQ29618158
Protein oxidation in aging, disease, and oxidative stressQ29619442
Biochemistry of oxygen toxicityQ34507383
Senescence-like growth arrest induced by hydrogen peroxide in human diploid fibroblast F65 cells.Q35217164
Involvement of the cyclin-dependent kinase inhibitor p16 (INK4a) in replicative senescence of normal human fibroblastsQ35927191
Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.Q36593741
The E7 gene of human papillomavirus type 16 is sufficient for immortalization of human epithelial cellsQ36688177
The molecular biology of apoptosisQ37688810
Replicative senescence: the human fibroblast comes of age.Q37951214
The activation of the rat copper/zinc superoxide dismutase gene by hydrogen peroxide through the hydrogen peroxide-responsive element and by paraquat and heat shock through the same heat shock elementQ38321737
A role for c-myc in chemically induced renal-cell deathQ40023931
Human papillomavirus E6 and E7: proteins which deregulate the cell cycleQ40422542
Heat shock proteins chaperoning life and deathQ40425306
Heat shock proteins: regulators of stress response and apoptosisQ40425316
Adaptive response and oxidative stressQ40500060
Replicative senescence of human fibroblast-like cells in cultureQ40825818
Cell and tissue responses to oxidative damageQ40848949
Interactions of human papillomavirus transforming proteins with the products of tumor suppressor genes.Q40856547
Free radicals as mediators of tissue injury and diseaseQ40895574
Replicative senescence: an old lives' tale?Q40968415
Replicative senescence: implications for in vivo aging and tumor suppressionQ41003046
Molecular analysis of H2O2-induced senescent-like growth arrest in normal human fibroblasts: p53 and Rb control G1 arrest but not cell replicationQ41045031
Response of a primary human fibroblast cell line to H2O2: senescence-like growth arrest or apoptosis?Q41113674
Transient adaptation of oxidative stress in mammalian cells.Q41353794
Double identity for proteins of the Bcl-2 familyQ41508318
The many roles of c-Myc in apoptosisQ41748386
Oxidative damage to mitochondria is mediated by the Ca(2+)-dependent inner-membrane permeability transitionQ42161186
Assays of oxidative DNA damage biomarkers 8-oxo-2'-deoxyguanosine and 8-oxoguanine in nuclear DNA and biological fluids by high-performance liquid chromatography with electrochemical detectionQ46826554
p21-induced cycle arrest in G1 protects cells from apoptosis induced by UV-irradiation or RNA polymerase II blockageQ47735165
Cytochrome c release and caspase activation in hydrogen peroxide- and tributyltin-induced apoptosisQ47851987
Cloning of senescent cell-derived inhibitors of DNA synthesis using an expression screenQ48084448
p21(Waf1/Cip1) protects against p53-mediated apoptosis of human melanoma cellsQ64382492
Chronic exposure of neonatal cardiac myocytes to hydrogen peroxide enhances the expression of catalaseQ71411058
Ceramide induces apoptosis via CPP32 activationQ71738609
Caspase-mediated cleavage of p21Waf1/Cip1 converts cancer cells from growth arrest to undergoing apoptosisQ74449037
A matter of life and cell deathQ77164675
Caspase 3 specifically cleaves p21WAF1/CIP1 in the earlier stage of apoptosis in SK-HEP-1 human hepatoma cellsQ77500551
P433issuePt 2
P407language of work or nameEnglishQ1860
P304page(s)543-551
P577publication date2000-04-01
P1433published inBiochemical JournalQ864221
P1476titleApoptosis or senescence-like growth arrest: influence of cell-cycle position, p53, p21 and bax in H2O2 response of normal human fibroblasts
P478volume347

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cites work (P2860)
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