Tyrosine phosphorylation of the vascular endothelial-growth-factor receptor-2 (VEGFR-2) is modulated by Rho proteins

scientific article published in June 2000

Tyrosine phosphorylation of the vascular endothelial-growth-factor receptor-2 (VEGFR-2) is modulated by Rho proteins is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1042/0264-6021:3480273
P932PMC publication ID1221063
P698PubMed publication ID10816419
P5875ResearchGate publication ID12502369

P2093author name stringBéliveau R
Gingras D
Lamy S
P2860cites workVascular endothelial growth factor receptor KDR tyrosine kinase activity is increased by autophosphorylation of two activation loop tyrosine residuesQ22008806
Different signal transduction properties of KDR and Flt1, two receptors for vascular endothelial growth factorQ24323249
Crystal structure of a small G protein in complex with the GTPase-activating protein rhoGAPQ24324015
Characterization of vascular endothelial growth factor's effect on the activation of protein kinase C, its isoforms, and endothelial cell growthQ24561921
Rho GTPases and the actin cytoskeletonQ27860579
Vascular endothelial growth factor stimulates tyrosine phosphorylation and recruitment to new focal adhesions of focal adhesion kinase and paxillin in endothelial cellsQ28240564
The vascular endothelial growth factor receptor KDR activates multiple signal transduction pathways in porcine aortic endothelial cellsQ28257153
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesisQ29547178
Vascular endothelial growth factor (VEGF) and its receptorsQ29615390
Bacterial toxins and the Rho GTP-binding protein: what microbes teach us about cell regulationQ33592308
Flk-1 as a target for tumor growth inhibition.Q34392604
Bacterial toxins that target Rho proteinsQ39779551
Consequences of angiogenesis for tumor progression, metastasis and cancer therapy.Q40400855
Vascular endothelial growth factor, a potent and selective angiogenic agentQ40943215
Efficient gene transfer to human endothelial cells using DNA complexed to adenovirus particlesQ41014136
ADP-ribosylation of the G protein Rho inhibits integrin regulation of tumor cell growthQ41197828
Full activation of the platelet-derived growth factor beta-receptor kinase involves multiple eventsQ42457318
Gln 63 of Rho is deamidated by Escherichia coli cytotoxic necrotizing factor-1.Q42799773
Cytotoxic necrotizing factor 1 from Escherichia coli and dermonecrotic toxin from Bordetella bronchiseptica induce p21(rho)-dependent tyrosine phosphorylation of focal adhesion kinase and paxillin in Swiss 3T3 cellsQ42801859
Platelet-derived growth factor receptor tyrosine phosphorylation requires protein geranylgeranylation but not farnesylationQ42807654
A small GTP-binding protein, Rho, associates with the platelet-derived growth factor type-beta receptor upon ligand binding.Q42825916
Dimerization as a regulatory mechanism in signal transductionQ46409691
Requirements for binding and signaling of the kinase domain receptor for vascular endothelial growth factorQ46693604
Rho GTPasesQ47724821
Post-transcriptional regulation of vascular endothelial growth factor by hypoxiaQ48066359
Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance.Q50626711
Escherichia coli cytotoxic necrotizing factor 1 (CNF1), a toxin that activates the Rho GTPase.Q54561665
Toxin-induced activation of the G protein p21 Rho by deamidation of glutamine.Q54564124
Vascular endothelial cell growth factor promotes tyrosine phosphorylation of mediators of signal transduction that contain SH2 domains. Association with endothelial cell proliferation.Q55065488
Dissection of Pathways Implicated in Integrin-mediated Actin Cytoskeleton AssemblyQ60716522
Dormancy of micrometastases: Balanced proliferation and apoptosis in the presence of angiogenesis suppressionQ71802927
Immunoglobulin-like domain 4-mediated receptor-receptor interactions contribute to platelet-derived growth factor-induced receptor dimerizationQ73316445
P407language of work or nameEnglishQ1860
P921main subjectphosphorylationQ242736
endotheliumQ111140
P304page(s)273-280
P577publication date2000-06-01
P1433published inBiochemical JournalQ864221
P1476titleTyrosine phosphorylation of the vascular endothelial-growth-factor receptor-2 (VEGFR-2) is modulated by Rho proteins
P478volume348 Pt 2

Reverse relations

cites work (P2860)
Q5159080767-kDa laminin receptor promotes internalization of cytotoxic necrotizing factor 1-expressing Escherichia coli K1 into human brain microvascular endothelial cells.
Q33512121A new procedure for determining the genetic basis of a physiological process in a non-model species, illustrated by cold induced angiogenesis in the carp
Q43162316Antiangiogenic mechanisms of simvastatin in retinal endothelial cells
Q36131307Ellagic acid, a phenolic compound, exerts anti-angiogenesis effects via VEGFR-2 signaling pathway in breast cancer
Q26250150Human umbilical vein endothelial cells and human dermal microvascular endothelial cells offer new insights into the relationship between lipid metabolism and angiogenesis
Q36561736Multifaceted role of Rho proteins in angiogenesis
Q35603936NO and angiogenesis
Q38720808Penduliflaworosin, a Diterpenoid from Croton crassifolius, Exerts Anti-Angiogenic Effect via VEGF Receptor-2 Signaling Pathway.
Q39294147Ras homolog gene family, member A promotes p53 degradation and vascular endothelial growth factor-dependent angiogenesis through an interaction with murine double minute 2 under hypoxic conditions
Q34774011Regulation of microvascular permeability by vascular endothelial growth factors
Q34451462Regulation of vascular endothelial growth factor receptor-2 activity by caveolin-1 and plasma membrane cholesterol.
Q35127972Regulation of vascular permeability by vascular endothelial growth factors.
Q35127959Rho GTPases and the regulation of endothelial permeability
Q38384340RhoA/mDia-1/profilin-1 signaling targets microvascular endothelial dysfunction in diabetic retinopathy
Q44604699Second hand smoke stimulates tumor angiogenesis and growth
Q37734546The role of endothelial progenitor cells in vascular repair after arterial injury and atherosclerotic plaque development
Q44275819Wf-536 prevents tumor metastasis by inhibiting both tumor motility and angiogenic actions

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