| scholarly article | Q13442814 |
| P50 | author | Mario Encinas | Q43061529 |
| P2093 | author name string | Jeffrey Milbrandt | |
| Eugene M Johnson | |||
| Sanjay Jain | |||
| P2860 | cites work | Insulin/insulin-like growth factor I hybrid receptors have different biological characteristics depending on the insulin receptor isoform involved | Q24301995 |
| Defects in enteric innervation and kidney development in mice lacking GDNF | Q24317594 | ||
| SLIT2-mediated ROBO2 signaling restricts kidney induction to a single site | Q24338774 | ||
| GFRalpha1 is an essential receptor component for GDNF in the developing nervous system and kidney | Q24649094 | ||
| The neuronal scaffold protein Shank3 mediates signaling and biological function of the receptor tyrosine kinase Ret in epithelial cells | Q24676241 | ||
| The GDNF family ligands and receptors - implications for neural development | Q28144957 | ||
| The GDNF family: signalling, biological functions and therapeutic value | Q28216478 | ||
| Oncogenic RET receptors display different autophosphorylation sites and substrate binding specificities | Q28277591 | ||
| Differential activities of the RET tyrosine kinase receptor isoforms during mammalian embryogenesis | Q28354358 | ||
| Sprouty1 is a critical regulator of GDNF/RET-mediated kidney induction | Q28508136 | ||
| Renal and neuronal abnormalities in mice lacking GDNF | Q28508969 | ||
| Gamma-secretase activity is dispensable for mesenchyme-to-epithelium transition but required for podocyte and proximal tubule formation in developing mouse kidney | Q28512634 | ||
| Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway. | Q53414254 | ||
| Renal agenesis and hypodysplasia in ret-k- mutant mice result from defects in ureteric bud development | Q60418568 | ||
| Prenatal diagnosis of congenital uropathies | Q69153211 | ||
| RET alternate splicing influences the interaction of activated RET with the SH2 and PTB domains of Shc, and the SH2 domain of Grb2 | Q73104133 | ||
| Edelfosine, apoptosis, MDR and Na+/H+ exchanger: induction mechanisms and treatment implications | Q73561375 | ||
| RET signaling is essential for migration, axonal growth and axon guidance of developing sympathetic neurons | Q74756232 | ||
| Distal ureter morphogenesis depends on epithelial cell remodeling mediated by vitamin A and Ret | Q28587600 | ||
| Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis | Q28589851 | ||
| Erk MAP kinase regulates branching morphogenesis in the developing mouse kidney | Q28590780 | ||
| Renal agenesis and the absence of enteric neurons in mice lacking GDNF | Q28594756 | ||
| Phospholipase C in Living Cells | Q29303618 | ||
| Defects in the kidney and enteric nervous system of mice lacking the tyrosine kinase receptor Ret | Q29620364 | ||
| How they begin and how they end: classic and new theories for the development and deterioration of congenital anomalies of the kidney and urinary tract, CAKUT. | Q33728700 | ||
| Phosphotyrosine 1062 is critical for the in vivo activity of the Ret9 receptor tyrosine kinase isoform | Q34097428 | ||
| Differential interaction of Enigma protein with the two RET isoforms. | Q34144280 | ||
| Accounting for specificity in receptor tyrosine kinase signaling | Q34312600 | ||
| Sprouty proteins regulate ureteric branching by coordinating reciprocal epithelial Wnt11, mesenchymal Gdnf and stromal Fgf7 signalling during kidney development. | Q34327414 | ||
| Congenital obstructive uropathy: its origin and contribution to end-stage renal disease in children | Q34354534 | ||
| The GDNF/RET signaling pathway and human diseases | Q34360698 | ||
| Phenotype variation in two-locus mouse models of Hirschsprung disease: tissue-specific interaction between Ret and Ednrb | Q34762174 | ||
| Biological activities, mechanisms of action and biomedical prospect of the antitumor ether phospholipid ET-18-OCH(3) (edelfosine), a proapoptotic agent in tumor cells | Q34946588 | ||
| Induction of apoptosis in human mitogen-activated peripheral blood T-lymphocytes by the ether phospholipid ET-18-OCH3: involvement of the Fas receptor/ligand system. | Q35029006 | ||
| A human yeast artificial chromosome containing the multiple endocrine neoplasia type 2B Ret mutation does not induce medullary thyroid carcinoma but does support the growth of kidneys and partially rescues enteric nervous system development in Ret-d | Q35083569 | ||
| Novel functions and signalling pathways for GDNF. | Q35210720 | ||
| Modulation of signalling by Sprouty: a developing story | Q35790325 | ||
| CD44 is required for two consecutive steps in HGF/c-Met signaling. | Q35805198 | ||
| Recent genetic studies of mouse kidney development | Q35893536 | ||
| Insulin-like growth factors I and II are produced in the metanephros and are required for growth and development in vitro | Q36529897 | ||
| A targeting mutation of tyrosine 1062 in Ret causes a marked decrease of enteric neurons and renal hypoplasia | Q37493754 | ||
| EGR1 target genes in prostate carcinoma cells identified by microarray analysis. | Q38308423 | ||
| Differential requirement of Tyr1062 multidocking site by RET isoforms to promote neural cell scattering and epithelial cell branching | Q38337406 | ||
| Mice expressing a dominant-negative Ret mutation phenocopy human Hirschsprung disease and delineate a direct role of Ret in spermatogenesis | Q40506925 | ||
| Regulation of sprouty expression by PLCgamma and calcium-dependent signals | Q40513281 | ||
| Tyrosine 981, a novel ret autophosphorylation site, binds c-Src to mediate neuronal survival | Q40591766 | ||
| Wnt11 and Ret/Gdnf pathways cooperate in regulating ureteric branching during metanephric kidney development. | Q40642802 | ||
| The long and short isoforms of Ret function as independent signaling complexes. | Q40721459 | ||
| Ureteric bud outgrowth in response to RET activation is mediated by phosphatidylinositol 3-kinase | Q40750881 | ||
| Development of cranial parasympathetic ganglia requires sequential actions of GDNF and neurturin | Q40846998 | ||
| Characterization of intracellular signals via tyrosine 1062 in RET activated by glial cell line-derived neurotrophic factor | Q40852922 | ||
| Signaling complexes and protein-protein interactions involved in the activation of the Ras and phosphatidylinositol 3-kinase pathways by the c-Ret receptor tyrosine kinase. | Q40854118 | ||
| Dominant effects of RET receptor misexpression and ligand-independent RET signaling on ureteric bud development. | Q40968789 | ||
| GFR alpha1-deficient mice have deficits in the enteric nervous system and kidneys. | Q41010725 | ||
| Glial-cell-line-derived neurotrophic factor is required for bud initiation from ureteric epithelium | Q41078366 | ||
| The molecular basis of embryonic kidney development | Q41122012 | ||
| A mutation at tyrosine 1062 in MEN2A-Ret and MEN2B-Ret impairs their transforming activity and association with shc adaptor proteins | Q42810812 | ||
| Deficiency of phospholipase C-gamma1 impairs renal development and hematopoiesis. | Q43826754 | ||
| Distinct biological properties of two RET isoforms activated by MEN 2A and MEN 2B mutations | Q44233386 | ||
| 3' Splicing variants of ret receptor tyrosine kinase are differentially expressed in mouse embryos and in adult mice | Q44448718 | ||
| P433 | issue | 3 | |
| P407 | language of work or name | English | Q1860 |
| P304 | page(s) | 321-333 | |
| P577 | publication date | 2006-02-01 | |
| P1433 | published in | Genes & Development | Q1524533 |
| P1476 | title | Critical and distinct roles for key RET tyrosine docking sites in renal development | |
| P478 | volume | 20 |
| Q48417724 | A common variant located in the 3'UTR of the RET gene is associated with protection from Hirschsprung disease |
| Q37424512 | Advances in early kidney specification, development and patterning |
| Q36284502 | Alternative splicing results in RET isoforms with distinct trafficking properties. |
| Q39979628 | Analysis of Ret knockin mice reveals a critical role for IKKs, but not PI 3-K, in neurotrophic factor-induced survival of sympathetic neurons. |
| Q42910496 | Angiotensin II-induced activation of c-Ret signaling is critical in ureteric bud branching morphogenesis |
| Q42860051 | Branching morphogenesis. |
| Q64950616 | Centrosome amplification disrupts renal development and causes cystogenesis. |
| Q34326028 | Complex pathogenesis of Hirschsprung's disease in a patient with hydrocephalus, vesico-ureteral reflux and a balanced translocation t(3;17)(p12;q11). |
| Q30579128 | DLG1 influences distal ureter maturation via a non-epithelial cell autonomous mechanism involving reduced retinoic acid signaling, Ret expression, and apoptosis |
| Q40100594 | Deciphering adaptor specificity in GFL-dependent RET-mediated proliferation and neurite outgrowth |
| Q30419212 | Deletion of the prorenin receptor from the ureteric bud causes renal hypodysplasia |
| Q64109223 | Development of the urogenital system is regulated via the 3'UTR of GDNF |
| Q64984008 | Developmental pathology of congenital kidney and urinary tract anomalies. |
| Q40000234 | Differential membrane compartmentalization of Ret by PTB-adaptor engagement |
| Q30481679 | Diminished Ret expression compromises neuronal survival in the colon and causes intestinal aganglionosis in mice. |
| Q38841103 | Distinct Temporal Regulation of RET Isoform Internalization: Roles of Clathrin and AP2. |
| Q40254769 | Engineering the recruitment of phosphotyrosine binding domain-containing adaptor proteins reveals distinct roles for RET receptor-mediated cell survival. |
| Q36827186 | Enteric nervous system development and Hirschsprung's disease: advances in genetic and stem cell studies |
| Q37455527 | Etv4 and Etv5 are required downstream of GDNF and Ret for kidney branching morphogenesis |
| Q52578627 | Expression profiles of congenital renal dysplasia reveal new insights into renal development and disease. |
| Q92252674 | FAT4 Fine-Tunes Kidney Development by Regulating RET Signaling |
| Q46704081 | GDNF and MAPK-ERK pathway signaling is reduced during nephrogenesis following maternal under-nutrition |
| Q28083626 | GDNF-Ret signaling in midbrain dopaminergic neurons and its implication for Parkinson disease |
| Q34661724 | GDNF/Ret signaling and renal branching morphogenesis: From mesenchymal signals to epithelial cell behaviors |
| Q28513713 | GLI3 repressor controls nephron number via regulation of Wnt11 and Ret in ureteric tip cells |
| Q39190736 | Gastrointestinal defects of the Gas1 mutant involve dysregulated Hedgehog and Ret signaling |
| Q37351552 | Genetic and developmental basis for urinary tract obstruction |
| Q26996583 | Genetic controls and cellular behaviors in branching morphogenesis of the renal collecting system |
| Q41238162 | Genetics of kidney development: pathogenesis of renal anomalies |
| Q33631798 | Glial cell line-derived neurotrophic factor induces cell proliferation in the mouse urogenital sinus |
| Q38116935 | Hirschsprung disease: a developmental disorder of the enteric nervous system. |
| Q34611546 | Hyperglycemia: GDNF-EGR1 pathway target renal epithelial cell migration and apoptosis in diabetic renal embryopathy |
| Q40500279 | Integrin-linked Kinase Controls Renal Branching Morphogenesis via Dual Specificity Phosphatase 8. |
| Q35977327 | Intracellular signal transduction and modification of the tumor microenvironment induced by RET/PTCs in papillary thyroid carcinoma |
| Q33525015 | Kidney development in the absence of Gdnf and Spry1 requires Fgf10. |
| Q36514895 | LDL Receptor-Related Protein 6 Modulates Ret Proto-Oncogene Signaling in Renal Development and Cystic Dysplasia. |
| Q43186033 | Loss of Sprouty1 rescues renal agenesis caused by Ret mutation. |
| Q39633034 | Loss of Sprouty2 partially rescues renal hypoplasia and stomach hypoganglionosis but not intestinal aganglionosis in Ret Y1062F mutant mice |
| Q27000375 | Lower urinary tract development and disease |
| Q49905672 | MAPK and PI3K Signaling: at the Crossroads of Neural Crest Development. |
| Q64059604 | MAPK/ERK Signaling in Regulation of Renal Differentiation |
| Q35902711 | Mammalian kidney development: principles, progress, and projections |
| Q47677533 | Maternal nutrient restriction inhibits ureteric bud branching but does not affect the duration of nephrogenesis in rats |
| Q30486719 | Maturation of ureter-bladder connection in mice is controlled by LAR family receptor protein tyrosine phosphatases |
| Q35112691 | Mitogen-activated protein kinase (MAPK) pathway regulates branching by remodeling epithelial cell adhesion |
| Q28507265 | Nephric duct insertion is a crucial step in urinary tract maturation that is regulated by a Gata3-Raldh2-Ret molecular network in mice |
| Q26776474 | Neurotrophic Factors and Their Potential Applications in Tissue Regeneration. |
| Q33944235 | Neurotrophic factor GDNF promotes survival of salivary stem cells |
| Q36970334 | Neurotrophic factor receptor RET: structure, cell biology, and inherited diseases |
| Q39991257 | Neurturin-mediated ret activation is required for retinal function |
| Q92949876 | New imaging tools to measure nephron number in vivo: opportunities for developmental nephrology |
| Q30514572 | Novel mechanisms of early upper and lower urinary tract patterning regulated by RetY1015 docking tyrosine in mice |
| Q33685678 | Organotypic specificity of key RET adaptor-docking sites in the pathogenesis of neurocristopathies and renal malformations in mice |
| Q33904019 | Patterning a complex organ: branching morphogenesis and nephron segmentation in kidney development |
| Q37256250 | QTL mapping of leukocyte telomere length in American Indians: the Strong Heart Family Study |
| Q46754712 | RET Gly691Ser mutation is associated with primary vesicoureteral reflux in the French-Canadian population from Quebec. |
| Q34166301 | RET PLCγ phosphotyrosine binding domain regulates Ca2+ signaling and neocortical neuronal migration. |
| Q40215482 | RET is dispensable for maintenance of midbrain dopaminergic neurons in adult mice. |
| Q38190360 | RET revisited: expanding the oncogenic portfolio |
| Q38510959 | RET-mediated gene expression pattern is affected by isoform but not oncogenic mutation. |
| Q37884393 | Receptor tyrosine kinases in kidney development |
| Q50078193 | Reciprocal Spatiotemporally Controlled Apoptosis Regulates Wolffian Duct Cloaca Fusion. |
| Q35241470 | Region-specific regulation of cell proliferation by FGF receptor signaling during the Wolffian duct development. |
| Q59335813 | Regulation of Renal Differentiation by Trophic Factors |
| Q36945522 | Renal abnormalities and their developmental origin |
| Q37848136 | Renin-angiotensin system in ureteric bud branching morphogenesis: insights into the mechanisms |
| Q37413081 | Ret function in muscle stem cells points to tyrosine kinase inhibitor therapy for facioscapulohumeral muscular dystrophy. |
| Q83229783 | Retrograde Ret signaling controls sensory pioneer axon outgrowth |
| Q34080638 | Sall1-dependent signals affect Wnt signaling and ureter tip fate to initiate kidney development |
| Q38418119 | Signaling during Kidney Development |
| Q37042855 | Stage specific requirement of Gfrα1 in the ureteric epithelium during kidney development |
| Q37350774 | Stimulatory and inhibitory signaling molecules that regulate renal branching morphogenesis |
| Q36555201 | Structure and physiology of the RET receptor tyrosine kinase |
| Q39000495 | The contribution of branching morphogenesis to kidney development and disease. |
| Q37158061 | The genetics and epigenetics of kidney development |
| Q39694457 | The many faces of RET dysfunction in kidney |
| Q35126928 | The multi-targeted tyrosine kinase inhibitor vandetanib plays a bifunctional role in non-small cell lung cancer cells |
| Q40008230 | The neurotrophic effects of glial cell line-derived neurotrophic factor on spinal motoneurons are restricted to fusimotor subtypes. |
| Q39455165 | The tyrosine phosphatase Shp2 acts downstream of GDNF/Ret in branching morphogenesis of the developing mouse kidney. |
| Q30300352 | The ureteric bud epithelium: morphogenesis and roles in metanephric kidney patterning |
| Q37634304 | To bud or not to bud: the RET perspective in CAKUT. |
| Q36551577 | Traditional and targeted exome sequencing reveals common, rare and novel functional deleterious variants in RET-signaling complex in a cohort of living US patients with urinary tract malformations |
| Q34395318 | Validating single-cell genomics for the study of renal development. |
| Q35928083 | Yap and Taz are required for Ret-dependent urinary tract morphogenesis |
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