Between new genetic discoveries and large randomized trials--neurological research in the era of systems medicine

scientific article published on 14 May 2013

Between new genetic discoveries and large randomized trials--neurological research in the era of systems medicine is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1038/EMBOR.2013.70
P932PMC publication ID3674454
P698PubMed publication ID23670197

P50authorMartin DichgansQ30422338
Stefan F LichtenthalerQ63092222
P2093author name stringThomas Misgeld
P2860cites workA mutation in APP protects against Alzheimer’s disease and age-related cognitive declineQ22251083
NLRP3 is activated in Alzheimer's disease and contributes to pathology in APP/PS1 miceQ24604235
Pathogenic protein seeding in Alzheimer disease and other neurodegenerative disordersQ26850298
The amyloid hypothesis of Alzheimer's disease: progress and problems on the road to therapeuticsQ27860914
Soluble protein oligomers in neurodegeneration: lessons from the Alzheimer's amyloid beta-peptideQ28131750
TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendritesQ28594138
Genome-wide association study identifies a variant in HDAC9 associated with large vessel ischemic strokeQ29417129
Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis.Q30511133
Microtubule stabilization reduces scarring and causes axon regeneration after spinal cord injuryQ30513561
2-photon imaging of phagocyte-mediated T cell activation in the CNS.Q30536629
Loss of ALS-associated TDP-43 in zebrafish causes muscle degeneration, vascular dysfunction, and reduced motor neuron axon outgrowthQ30538184
Cerebral amyloid-β proteostasis is regulated by the membrane transport protein ABCC1 in miceQ34212267
Three-dimensional imaging of the unsectioned adult spinal cord to assess axon regeneration and glial responses after injury.Q34242950
ABC transporters B1, C1 and G2 differentially regulate neuroregeneration in miceQ34251174
Purified and synthetic Alzheimer's amyloid beta (Aβ) prionsQ36079533
Secretome protein enrichment identifies physiological BACE1 protease substrates in neuronsQ36103683
β-Site amyloid precursor protein (APP)-cleaving enzyme 1 (BACE1)-deficient mice exhibit a close homolog of L1 (CHL1) loss-of-function phenotype involving axon guidance defectsQ36385744
Divergent roles of ALS-linked proteins FUS/TLS and TDP-43 intersect in processing long pre-mRNAsQ36650975
Advances in understanding the molecular basis of frontotemporal dementiaQ36775677
Mitochondrial DNA polymorphisms specifically modify cerebral β-amyloid proteostasisQ36960466
Axonal transport deficits and neurodegenerative diseasesQ38077679
The changing scene of amyotrophic lateral sclerosisQ38086771
Loss of fused in sarcoma (FUS) promotes pathological Tau splicingQ42138048
Generation of Alzheimer disease-associated amyloid β42/43 peptide by γ-secretase can be inhibited directly by modulation of membrane thicknessQ42202065
Commensal microbiota and myelin autoantigen cooperate to trigger autoimmune demyelination.Q48819558
Alzheimer's research. Stopping Alzheimer's before it startsQ84824173
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)489-492
P577publication date2013-05-14
P1433published inEMBO ReportsQ5323356
P1476titleBetween new genetic discoveries and large randomized trials--neurological research in the era of systems medicine
P478volume14

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Q38299414Advances in the therapy of Alzheimer's disease: targeting amyloid beta and tau and perspectives for the futurecites workP2860

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