Novel glimepiride derivatives with potential as double-edged swords against type II diabetes

scientific article published in February 2010

Novel glimepiride derivatives with potential as double-edged swords against type II diabetes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3109/13813450903575720
P698PubMed publication ID20166804

P50authorAnna C. Crecelius-vitzQ42609948
Günter MüllerQ42676778
P2093author name stringElisabeth-Ann Dearey
Eva-Maria Wetekam
Susanne Wied
Wendelin Frick
Andrea Schulz
Detlev Hartz
Raymond Okonomopulos
P2860cites workReconstitution of IKATP: an inward rectifier subunit plus the sulfonylurea receptorQ24304448
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KATP channels as molecular sensors of cellular metabolismQ28303315
Glimepiride block of cloned beta-cell, cardiac and smooth muscle K(ATP) channelsQ28363877
Analysis of lipolysis in adipocytes using a fluorescent fatty acid derivativeQ28574349
Tissue specificity of sulfonylureas: studies on cloned cardiac and beta-cell K(ATP) channelsQ48933175
Absolute bioavailability of glimepiride (Amaryl) after oral administrationQ33184801
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Cloning of the beta cell high-affinity sulfonylurea receptor: a regulator of insulin secretionQ34308492
Glycosylphosphatidylinositol (GPI)-anchored proteinsQ34522931
Coordinate regulation of glucose transporter function, number, and gene expression by insulin and sulfonylureas in L6 rat skeletal muscle cellsQ34576372
Cellular microparticles: what are they bad or good for?Q35181674
Possible role of cytosolic free calcium concentrations in mediating insulin resistance of obesity and hyperinsulinemiaQ35594111
K(ATP) channel therapeutics at the bedsideQ36161668
Direct photoaffinity labeling of the putative sulfonylurea receptor in rat beta-cell tumor membranes by [3H]glibenclamideQ36312899
Continuous, clonal, insulin- and somatostatin-secreting cell lines established from a transplantable rat islet cell tumorQ36394174
4'-Amino-benzamido-taurocholic acid selectively solubilizes glycosyl-phosphatidylinositol-anchored membrane proteins and improves lipolytic cleavage of their membrane anchors by specific phospholipasesQ36745349
Differential interaction of glimepiride and glibenclamide with the beta-cell sulfonylurea receptor. I. Binding characteristicsQ36749000
Differential interaction of glimepiride and glibenclamide with the beta-cell sulfonylurea receptor. II. Photoaffinity labeling of a 65 kDa protein by [3H]glimepirideQ36749004
Cloning and functional expression of the cDNA encoding a novel ATP-sensitive potassium channel subunit expressed in pancreatic beta-cells, brain, heart and skeletal muscleQ36789864
Lipid droplets: a classic organelle with new outfitsQ36801009
Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at beta-cellsQ36831665
Characterization of the molecular mode of action of the sulfonylurea, glimepiride, at adipocytesQ36831669
Induced translocation of glycosylphosphatidylinositol-anchored proteins from lipid droplets to adiposomes in rat adipocytesQ37395903
Identification and characterization of microvesicles secreted by 3T3-L1 adipocytes: redox- and hormone-dependent induction of milk fat globule-epidermal growth factor 8-associated microvesiclesQ38302097
Redistribution of glycolipid raft domain components induces insulin-mimetic signaling in rat adipocytesQ39459824
Hydrogen peroxide-induced translocation of glycolipid-anchored (c)AMP-hydrolases to lipid droplets mediates inhibition of lipolysis in rat adipocytesQ39572907
In vitro effects of a sulfonylurea on insulin action in adipocytes. Potentiation of insulin-stimulated hexose transportQ40683763
Molecular structure of the glibenclamide binding site of the beta-cell K(ATP) channelQ40797523
Structural requirements of sulphonylureas and analogues for interaction with sulphonylurea receptor subtypesQ40926769
Interaction of N-benzoyl-D-phenylalanine and related compounds with the sulphonylurea receptor of beta-cellsQ41048513
Do adipocytes contain high affinity sulfonylurea receptorsQ41483485
Mammalian GPI proteins: sorting, membrane residence and functionsQ41608164
Sulfonylurea-stimulated glucose transport association with diacylglycerollike activation of protein kinase C in BC3H1 myocytesQ41716840
Inhibition of lipolysis by palmitate, H2O2 and the sulfonylurea drug, glimepiride, in rat adipocytes depends on cAMP degradation by lipid dropletsQ42523469
Association of (c)AMP-degrading glycosylphosphatidylinositol-anchored proteins with lipid droplets is induced by palmitate, H2O2 and the sulfonylurea drug, glimepiride, in rat adipocytes.Q42523474
Health care and health status and outcomes for patients with type 2 diabetesQ43791958
Insulin and glyburide increase cytosolic free-Ca2+ concentration in isolated rat adipocytesQ44707477
Induced release of membrane vesicles from rat adipocytes containing glycosylphosphatidylinositol-anchored microdomain and lipid droplet signalling proteinsQ46245778
Coordinated regulation of esterification and lipolysis by palmitate, H2O2 and the anti-diabetic sulfonylurea drug, glimepiride, in rat adipocytesQ46369604
Translocation of glycosylphosphatidylinositol-anchored proteins from plasma membrane microdomains to lipid droplets in rat adipocytes is induced by palmitate, H2O2, and the sulfonylurea drug glimepirideQ46755431
Identification of the high-affinity tolbutamide site on the SUR1 subunit of the K(ATP) channelQ48917262
P433issue1
P921main subjecttype 2 diabetesQ3025883
P304page(s)3-20
P577publication date2010-02-01
P1433published inArchives of Physiology and BiochemistryQ15746394
P1476titleNovel glimepiride derivatives with potential as double-edged swords against type II diabetes
P478volume116