Effect of ethanol on fluoroquinolone efficacy in a rat model of pneumococcal pneumonia

scientific article published in January 2006

Effect of ethanol on fluoroquinolone efficacy in a rat model of pneumococcal pneumonia is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1128/AAC.50.1.210-219.2006
P932PMC publication ID1346821
P698PubMed publication ID16377688

P2093author name stringMei Yue
Keith M Olsen
Laurel C Preheim
Mary U Snitily
Martha Gentry-Nielsen
P2860cites workGuidelines for the management of adults with community-acquired pneumonia. Diagnosis, assessment of severity, antimicrobial therapy, and preventionQ28201389
Maintaining fluoroquinolone class efficacy: review of influencing factorsQ30310427
MoxifloxacinQ33588540
A review of the comparative in-vitro activities of 12 antimicrobial agents, with a focus on five new respiratory quinolones'.Q33670442
Activities of newer fluoroquinolones against Streptococcus pneumoniae clinical isolates including those with mutations in the gyrA, parC, and parE lociQ33976055
Application of fluoroquinolone pharmacodynamicsQ34076026
Comparison of levofloxacin, alatrofloxacin, and vancomycin for prophylaxis and treatment of experimental foreign-body-associated infection by methicillin-resistant Staphylococcus aureusQ34107094
Evaluation of the clinical microbiology profile of moxifloxacinQ34183540
Moxifloxacin: clinical efficacy and safetyQ34189561
Clinical role of protein binding of quinolonesQ34774058
Pharmacokinetics of trovafloxacin (CP-99,219), a new quinolone, in rats, dogs, and monkeysQ35122822
Intrapulmonary pharmacokinetics of azithromycin in healthy volunteers given five oral dosesQ35129323
Trovafloxacin, a new fluoroquinolone with potent activity against Streptococcus pneumoniaeQ35133005
Pulmonary disposition of antimicrobial agents: methodological considerationsQ35447413
In vitro activity of CP-99,219, a new fluoroquinolone, against clinical isolates of gram-positive bacteriaQ35809411
Hepatic, metabolic and toxic effects of ethanol: 1991 updateQ37414939
Cellular iron metabolism in health and diseaseQ37783194
Update of practice guidelines for the management of community-acquired pneumonia in immunocompetent adultsQ37868241
Activation of the oxidative metabolism in human polymorphonuclear neutrophilic granulocytes: the role of immuno-modulating cytokinesQ38010176
Pharmacodynamic activity and efficacy of linezolid in a rat model of pneumococcal pneumoniaQ39651829
Pharmacodynamics of a Novel Des-F(6)-Quinolone, BMS-284756, against Streptococcus pneumoniae in the Thigh Infection ModelQ39746333
Trovafloxacin in treatment of rabbits with experimental meningitis caused by high-level penicillin-resistant Streptococcus pneumoniaeQ39784239
Levofloxacin. A review of its antibacterial activity, pharmacokinetics and therapeutic efficacyQ40390211
The chemistry and biological profile of trovafloxacinQ41530540
Comparative antibiotic dose-effect relations at several dosing intervals in murine pneumonitis and thigh-infection modelsQ42169493
Steady-state intrapulmonary concentrations of moxifloxacin, levofloxacin, and azithromycin in older adultsQ42621706
Effects of granulocyte colony-stimulating factor in cirrhotic rats with pneumococcal pneumoniaQ43612345
Capsular types and outcome of bacteremic pneumococcal disease in the antibiotic era.Q44037186
Pharmacokinetic study of levofloxacin in rat blood and bile by microdialysis and high-performance liquid chromatographyQ44108067
Efficacy of liposome-encapsulated ciprofloxacin compared with ciprofloxacin and ceftriaxone in a rat model of pneumococcal pneumoniaQ44257279
An international prospective study of pneumococcal bacteremia: correlation with in vitro resistance, antibiotics administered, and clinical outcomeQ44510164
Concentrations of trovafloxacin in bronchial mucosa, epithelial lining fluid, alveolar macrophages and serum after administration of single or multiple oral doses to patients undergoing fibre-optic bronchoscopyQ44511523
High-dose, short-course levofloxacin for community-acquired pneumonia: a new treatment paradigmQ44573499
Levofloxacin and trovafloxacin inhibition of experimental fracture-healingQ44579509
Effect of cirrhosis on antibiotic efficacy in a rat model of pneumococcal pneumoniaQ45255735
Alcohol research in the Veterans Administration: a success storyQ45336532
Determination of quinolone antibiotics in growth media by reversed-phase high-performance liquid chromatographyQ47882319
Pharmacokinetics of the 8-methoxyquinolone, moxifloxacin: tissue distribution in male ratsQ48177410
Comparative susceptibility to penicillin and quinolones of 1385 Streptococcus pneumoniae isolates. Austrian Bacterial Surveillance Network.Q54090934
Effect of cirrhosis on the production and efficacy of pneumococcal capsular antibody in a rat model.Q54260950
Pulmonary recruitment, adherence, and chemotaxis of neutrophils in a rat model of cirrhosis and pneumococcal pneumoniaQ68064107
Pneumococcal pneumonia in a rat model of cirrhosis: effects of cirrhosis on pulmonary defense mechanisms against Streptococcus pneumoniaeQ68176345
A simple method for collection of blood from the rat footQ68261885
Estimation of volume of epithelial lining fluid recovered by lavage using urea as marker of dilutionQ68861405
Quantification of cells recovered by bronchoalveolar lavage. Comparison of cytocentrifuge preparations with the filter methodQ70231763
Determination of trovafloxacin, a new quinolone antibiotic, in biological samples by reversed-phase high-performance liquid chromatographyQ71088303
Failure of intensive care unit support to influence mortality from pneumococcal bacteremiaQ71655334
The effect of ethanol ingestion on killing of Streptococcus pneumoniae, Staphylococcus aureus and Staphylococcus epidermidis by rat neutrophilsQ71710865
Ethanol ingestion impairs neutrophil bactericidal mechanisms against Streptococcus pneumoniaeQ71951872
Fatty liver in the rat after prolonged intake of ethanol with a nutritionally adequate new liquid dietQ72213153
Pharmacokinetics and safety of trovafloxacin in healthy male volunteers following administration of single intravenous doses of the prodrug, alatrofloxacinQ73508354
Comparative in vivo activity of gemifloxacin in a rat model of respiratory tract infectionQ73819635
Grepafloxacin pharmacokinetics in individuals with hepatic dysfunctionQ74059513
Practice guidelines for the management of community-acquired pneumonia in adults. Infectious Diseases Society of AmericaQ74315684
Community-acquired pneumoniaQ75190399
Ethanol feeding does not affect the efficacy or pharmacokinetics of azithromycin, trovafloxacin, or ceftriaxone in a rat model of pneumococcal pneumoniaQ77889875
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectpneumoniaQ12192
P304page(s)210-219
P577publication date2006-01-01
P1433published inAntimicrobial Agents and ChemotherapyQ578004
P1476titleEffect of ethanol on fluoroquinolone efficacy in a rat model of pneumococcal pneumonia
P478volume50

Reverse relations

cites work (P2860)
Q37914449Alcohol abuse and Streptococcus pneumoniae infections: consideration of virulence factors and impaired immune responses
Q37293669Animal models of Streptococcus pneumoniae disease
Q37867260Continuing education: alternative approaches to optimizing antimicrobial pharmacodynamics in critically ill patients
Q94528468Investigating the effect of some fluoroquinolones on C-reactive protein levels and ACh-Induced blood pressure reduction deviations after aging of diabetes in STZ-Induced diabetic wistar rats
Q41262080Prediction of the pharmacokinetics and tissue distribution of levofloxacin in humans based on an extrapolated PBPK model

Search more.