Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5.

scientific article published on 5 October 2008

Epigenetic restriction of embryonic cell lineage fate by methylation of Elf5. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1038/NCB1786
P932PMC publication ID2635539
P698PubMed publication ID18836439
P5875ResearchGate publication ID23300942

P50authorWolf ReikQ15994704
Myriam HembergerQ63727498
Zofia E MadejaQ47156185
P2093author name stringWendy Dean
Diana Lucifero
Claire Dawson
Ray Kit Ng
P2860cites workZ/AP, a double reporter for cre-mediated recombination.Q52178130
Potential of isolated mouse inner cell masses to form trophectoderm derivatives in vivoQ54464424
Cell lineage-specific undermethylation of mouse repetitive DNAQ59067144
Differential expression of angiogenic and vasodilatory factors by invasive trophoblast giant cells depending on depth of invasionQ63407349
Do trophectoderm and inner cell mass cells in the mouse blastocyst maintain discrete lineages?Q68687144
A quantitative analysis of cell allocation to trophectoderm and inner cell mass in the mouse blastocystQ69721372
Ability of outside cells from preimplantation mouse embryos to form inner cell mass derivativesQ71848833
Stochastic patterning in the mouse pre-implantation embryoQ81542210
Determination of the consensus DNA-binding sequence and a transcriptional activation domain for ESE-2Q24669962
A bivalent chromatin structure marks key developmental genes in embryonic stem cellsQ27860977
Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocystQ28506141
Eomesodermin is required for mouse trophoblast development and mesoderm formationQ28507697
Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterningQ28509022
Elf5 is an epithelium-specific, fibroblast growth factor-sensitive transcription factor in the embryonic lungQ28511303
The SRA protein Np95 mediates epigenetic inheritance by recruiting Dnmt1 to methylated DNAQ28589108
Quantitative expression of Oct-3/4 defines differentiation, dedifferentiation or self-renewal of ES cellsQ28590205
Interaction between Oct3/4 and Cdx2 determines trophectoderm differentiationQ28594991
Polycomb complexes repress developmental regulators in murine embryonic stem cellsQ29547274
Chromatin signatures of pluripotent cell linesQ29614675
Promotion of trophoblast stem cell proliferation by FGF4Q29614847
Stability and flexibility of epigenetic gene regulation in mammalian developmentQ29615922
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genomeQ29616819
Chromosome-wide and promoter-specific analyses identify sites of differential DNA methylation in normal and transformed human cellsQ29618090
Expression of the T-box gene Eomesodermin during early mouse development.Q30630109
Global mapping of DNA methylation in mouse promoters reveals epigenetic reprogramming of pluripotency genesQ33347134
Reduced genomic cytosine methylation and defective cellular differentiation in embryonic stem cells lacking CpG binding proteinQ33836835
Dynamic reprogramming of DNA methylation in the early mouse embryo.Q34108785
Formation of germ-line chimaeras from embryo-derived teratocarcinoma cell linesQ34267275
An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryoQ34476936
Transcription factor TEAD4 specifies the trophectoderm lineage at the beginning of mammalian developmentQ34697962
Establishment and maintenance of genomic methylation patterns in mouse embryonic stem cells by Dnmt3a and Dnmt3b.Q35169651
Lineage allocation and cell polarity during mouse embryogenesis.Q35844050
Cell and molecular regulation of the mouse blastocystQ36506449
The first cell-fate decisions in the mouse embryo: destiny is a matter of both chance and choice.Q36522402
Stem cells and lineage development in the mammalian blastocystQ36772074
Clonal analysis of early mammalian developmentQ39427491
Embryo-derived stem cells: a tool for elucidating the developmental genetics of the mouseQ39729904
Severe global DNA hypomethylation blocks differentiation and induces histone hyperacetylation in embryonic stem cells.Q40025706
De novo DNA cytosine methyltransferase activities in mouse embryonic stem cellsQ41161849
Trophoblast stem cells differentiate in vitro into invasive trophoblast giant cellsQ44956274
Undermethylation of structural gene sequences in extraembryonic lineages of the mouse.Q51207966
Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation.Q52086106
Inhibition of trophoblast stem cell potential in chorionic ectoderm coincides with occlusion of the ectoplacental cavity in the mouse.Q52116904
Expression of Fgfr2 in the early mouse embryo indicates its involvement in preimplantation development.Q52175661
P433issue11
P304page(s)1280-1290
P577publication date2008-10-05
P1433published inNature Cell BiologyQ1574111
P1476titleEpigenetic restriction of embryonic cell lineage fate by methylation of Elf5.
P478volume10

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cites work (P2860)
Q40090445A Resource for the Transcriptional Signature of Bona Fide Trophoblast Stem Cells and Analysis of Their Embryonic Persistence
Q64039505A new Elf5 BAC transgenic mouse model for tracing Elf5 cell lineages in adult tissues
Q34044292ADP-ribosyltransferases Parp1 and Parp7 safeguard pluripotency of ES cells
Q90262225ATR expands embryonic stem cell fate potential in response to replication stress
Q50137372Activation of the Aryl Hydrocarbon Receptor Interferes with Early Embryonic Development
Q35580774Activin/nodal signaling switches the terminal fate of human embryonic stem cell-derived trophoblasts.
Q35207572Adaptive mechanisms controlling uterine spiral artery remodeling during the establishment of pregnancy
Q39221968Analysis of human embryos from zygote to blastocyst reveals distinct gene expression patterns relative to the mouse
Q37177982BMP4-directed trophoblast differentiation of human embryonic stem cells is mediated through a ΔNp63+ cytotrophoblast stem cell state.
Q36595637BRACHYURY and CDX2 mediate BMP-induced differentiation of human and mouse pluripotent stem cells into embryonic and extraembryonic lineages
Q36289551BRG1 Governs Nanog Transcription in Early Mouse Embryos and Embryonic Stem Cells via Antagonism of Histone H3 Lysine 9/14 Acetylation
Q40278733Bovine trophectoderm cells induced from bovine fibroblasts with induced pluripotent stem cell reprogramming factors.
Q39128718CDX2 regulates multiple trophoblast genes in bovine trophectoderm CT-1 cells.
Q50422040Capturing and Interconverting Embryonic Cell Fates in a Dish.
Q28507649Cellular heterogeneity during embryonic stem cell differentiation to epiblast stem cells is revealed by the ShcD/RaLP adaptor protein
Q41216041Changes in chromosome territory position within the nucleus reflect alternations in gene expression related to embryonic lineage specification
Q34938871Changes in sub-cellular localisation of trophoblast and inner cell mass specific transcription factors during bovine preimplantation development
Q33549693Characterization of trophoblast and extraembryonic endoderm cell lineages derived from rat preimplantation embryos
Q30466805Child health, developmental plasticity, and epigenetic programming
Q38258849Chromatin dynamics in the regulation of cell fate allocation during early embryogenesis
Q33881683Chromatin environment of histone variant H3.3 revealed by quantitative imaging and genome-scale chromatin and DNA immunoprecipitation.
Q58705996Combinatorial Smad2/3 Activities Downstream of Nodal Signaling Maintain Embryonic/Extra-Embryonic Cell Identities during Lineage Priming
Q48183399Comparative analysis of mouse and human placentae across gestation reveals species-specific regulators of placental development.
Q36729758Complete and unidirectional conversion of human embryonic stem cells to trophoblast by BMP4
Q37260904Cripto is essential to capture mouse epiblast stem cell and human embryonic stem cell pluripotency.
Q38090068DNA methylation and methylcytosine oxidation in cell fate decisions
Q38061120DNA methylation dynamics during the mammalian life cycle
Q38086773DNA methylation dynamics in health and disease
Q37772901DNA methylation in cell differentiation and reprogramming: an emerging systematic view
Q50554934DNA methylation profiles define stem cell identity and reveal a tight embryonic-extraembryonic lineage boundary.
Q28534357DNA methylation restricts lineage-specific functions of transcription factor Gata4 during embryonic stem cell differentiation
Q29616796DNA methylation: roles in mammalian development
Q37361953DNA methyltransferases and TETs in the regulation of differentiation and invasiveness of extra-villous trophoblasts.
Q42777328Defining the three cell lineages of the human blastocyst by single-cell RNA-seq.
Q46645514Depletion of Suds3 reveals an essential role in early lineage specification
Q37581659Derivation and maintenance of murine trophoblast stem cells under defined conditions
Q61802290Derivation of Haploid Trophoblast Stem Cells via Conversion In Vitro
Q89673842Derivation of trophoblast stem cells from naïve human pluripotent stem cells
Q38263164Developmental plasticity, cell fate specification and morphogenesis in the early mouse embryo.
Q39900486Differences in the epigenetic and reprogramming properties of pluripotent and extra-embryonic stem cells implicate chromatin remodelling as an important early event in the developing mouse embryo
Q41815409Direct reprogramming to multipotent trophoblast stem cells, and is pluripotency needed for regenerative medicine either?
Q33934698Distinct histone modifications in stem cell lines and tissue lineages from the early mouse embryo
Q64457417Distinct nuclear localization patterns of DNA methyltransferases in developing and mature mammalian retina
Q57285522Divergent wiring of repressive and active chromatin interactions between mouse embryonic and trophoblast lineages
Q36223582Down-regulation of Cdx2 in colorectal carcinoma cells by the Raf-MEK-ERK 1/2 pathway
Q29617398Dynamic regulation of 5-hydroxymethylcytosine in mouse ES cells and during differentiation
Q37961978Dynamic regulation of DNA methylation during mammalian development
Q30383247ELF5 isoform expression is tissue-specific and significantly altered in cancer.
Q34539617ELF5 suppresses estrogen sensitivity and underpins the acquisition of antiestrogen resistance in luminal breast cancer.
Q51659964ELF5 transcription factor expression during gestation in humans and rats - an immunohistochemical analysis.
Q50700225ELF5-enforced transcriptional networks define an epigenetically regulated trophoblast stem cell compartment in the human placenta.
Q50787831Ectopic expression of Fgf3 leads to aberrant lineage segregation in the mouse parthenote preimplantation embryos.
Q38356103Elf5 conditional knockout mice reveal its role as a master regulator in mammary alveolar development: failure of Stat5 activation and functional differentiation in the absence of Elf5.
Q28594878Elf5 counteracts precocious trophoblast differentiation by maintaining Sox2 and 3 and inhibiting Hand1 expression
Q38904870Elf5 inhibits TGF-β-driven epithelial-mesenchymal transition in prostate cancer by repressing SMAD3 activation
Q41718630Elf5 regulates mammary gland stem/progenitor cell fate by influencing notch signaling
Q51849873Elf5 regulation in the trophectoderm.
Q36406398Elf5-centered transcription factor hub controls trophoblast stem cell self-renewal and differentiation through stoichiometry-sensitive shifts in target gene networks
Q37257137Embryonic stem cell-derived trophoblast differentiation: a comparative review of the biology, function, and signaling mechanisms
Q34327033Endogenous retroviruses function as species-specific enhancer elements in the placenta
Q41640781Endometrial Cancer-Associated FGF18 Expression Is Reduced by Bazedoxifene in Human Endometrial Stromal Cells In Vitro and in Murine Endometrium
Q38626695Epigenesis and plasticity of mouse trophoblast stem cells
Q61818546Epigenetic Mechanisms Influencing Epithelial to Mesenchymal Transition in Bladder Cancer
Q41471486Epigenetic Regulation of miR-29s Affects the Lactation Activity of Dairy Cow Mammary Epithelial Cells
Q38151517Epigenetic choreography of stem cells: the DNA demethylation episode of development
Q37551606Epigenetic dynamics of stem cells and cell lineage commitment: digging Waddington's canal
Q37504694Epigenetic mechanisms that underpin metabolic and cardiovascular diseases
Q42573647Epigenetic memory of the first cell fate decision prevents complete ES cell reprogramming into trophoblast.
Q34143430Epigenetic modifications in pluripotent and differentiated cells
Q89542483Epigenetic regulation in development: is the mouse a good model for the human?
Q35550740Epigenetic regulation of Elf5 is associated with epithelial-mesenchymal transition in urothelial cancer
Q43213960Epigenetics and the control of multicellularity. Workshop on chromatin at the nexus of cell division and differentiation
Q57970772Epigenomics - Impact for Drug Safety Sciences
Q36121103Epithelial cell identity in hyperplastic precursors of breast cancer
Q37426774Eset partners with Oct4 to restrict extraembryonic trophoblast lineage potential in embryonic stem cells
Q38836808Establishment of a novel human embryonic stem cell-derived trophoblastic spheroid implantation model
Q35954436Establishment of epigenetic patterns in development
Q45971232Establishment of mouse expanded potential stem cells.
Q92502791Establishment of porcine and human expanded potential stem cells
Q28586266Ets2-dependent trophoblast signalling is required for gastrulation progression after primitive streak initiation
Q28507082Examination of transcriptional networks reveals an important role for TCFAP2C, SMARCA4, and EOMES in trophoblast stem cell maintenance
Q57469019Extracellular glucose levels in cultures of undifferentiated mouse trophoblast stem cells affect gene expression during subsequent differentiation with replicable cell line-dependent variation
Q34574568FGF4-dependent stem cells derived from rat blastocysts differentiate along the trophoblast lineage
Q24615539Foxa1 functions as a pioneer transcription factor at transposable elements to activate Afp during differentiation of embryonic stem cells
Q92571871GADD45 promotes locus-specific DNA demethylation and 2C cycling in embryonic stem cells
Q37431135GATA3 is selectively expressed in the trophectoderm of peri-implantation embryo and directly regulates Cdx2 gene expression
Q41960997Genome-wide regulation of 5hmC, 5mC, and gene expression by Tet1 hydroxylase in mouse embryonic stem cells
Q37135333Genomic imprinting in Singapore. Workshop on Genomic Imprinting
Q38622592Germline and Pluripotent Stem Cells
Q34540964Global DNA hypomethylation prevents consolidation of differentiation programs and allows reversion to the embryonic stem cell state
Q38591860Hallmarks of pluripotency
Q33531789Histone H3 lysine 27 methylation asymmetry on developmentally-regulated promoters distinguish the first two lineages in mouse preimplantation embryos
Q37086490Human pluripotent stem cells as a model of trophoblast differentiation in both normal development and disease
Q39887420Impact of the periconceptional environment on the programming of adult disease
Q52655487Integrin α2 marks a niche of trophoblast progenitor cells in first trimester human placenta.
Q34452305LSH and G9a/GLP complex are required for developmentally programmed DNA methylation
Q35077143Lineage conversion of murine extraembryonic trophoblast stem cells to pluripotent stem cells.
Q42492724Lineage specific methylation of the Elf5 promoter in mammary epithelial cells.
Q37523271Making a firm decision: multifaceted regulation of cell fate in the early mouse embryo
Q36373786Maternal diets trigger sex-specific divergent trajectories of gene expression and epigenetic systems in mouse placenta
Q90168443Mechanisms of early placental development in mouse and humans
Q39045061Mechanisms of pluripotency maintenance in mouse embryonic stem cells
Q47171209Mechanisms of transcription factor-mediated direct reprogramming of mouse embryonic stem cells to trophoblast stem-like cells
Q36195420Model systems for studying trophoblast differentiation from human pluripotent stem cells
Q48148031Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions
Q37772394Molecular basis of the first cell fate determination in mouse embryogenesis
Q38736146Molecular features of cellular reprogramming and development
Q48164997NSD1 inactivation defines an immune cold, DNA hypomethylated subtype in squamous cell carcinoma
Q38089266Non-canonical functions of the DNA methylome in gene regulation
Q41964037NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate
Q39557781Pancreatic β cell identity is maintained by DNA methylation-mediated repression of Arx.
Q46943948Paracrine effects of embryo-derived FGF4 and BMP4 during pig trophoblast elongation
Q33692490Phosphatidylinositol 3 kinase modulation of trophoblast cell differentiation
Q40737024Plet1 is an epigenetically regulated cell surface protein that provides essential cues to direct trophoblast stem cell differentiation.
Q36119496Pluripotency in the embryo and in culture
Q38323562Regulation of drug transporter expression and function in the placenta.
Q34795267Regulation of lineage specific DNA hypomethylation in mouse trophectoderm
Q46329417Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa
Q26829560Reprogramming DNA methylation in the mammalian life cycle: building and breaking epigenetic barriers
Q34038104Reprogramming in vivo produces teratomas and iPS cells with totipotency features.
Q54388639Reprogramming of trophoblast stem cells into pluripotent stem cells by Oct4.
Q35096190Retroviruses facilitate the rapid evolution of the mammalian placenta.
Q43249097Roles of CDX2 and EOMES in human induced trophoblast progenitor cells.
Q35694096SATB homeobox proteins regulate trophoblast stem cell renewal and differentiation
Q41862614Selection of accurate reference genes in mouse trophoblast stem cells for reverse transcription-quantitative polymerase chain reaction
Q28744059Sex- and diet-specific changes of imprinted gene expression and DNA methylation in mouse placenta under a high-fat diet
Q46320040Single-cell gene expression of the bovine blastocyst.
Q36945242Single-stranded DNA binding protein Ssbp3 induces differentiation of mouse embryonic stem cells into trophoblast-like cells.
Q38824735Stem cell insights into human trophoblast lineage differentiation
Q43866621Stem cells: Reprogramming in situ
Q37410905Synergistic mechanisms of DNA demethylation during transition to ground-state pluripotency
Q36257674TSA and BIX-01294 Induced Normal DNA and Histone Methylation and Increased Protein Expression in Porcine Somatic Cell Nuclear Transfer Embryos
Q51896182Targets and dynamics of promoter DNA methylation during early mouse development
Q28504716Tet1 and Tet2 regulate 5-hydroxymethylcytosine production and cell lineage specification in mouse embryonic stem cells
Q37315335The Epigenetics of Normal Pregnancy
Q92852980The Role of Epigenetics in Placental Development and the Etiology of Preeclampsia
Q34425899The epigenetic landscape of mammary gland development and functional differentiation
Q33755392The placenta: transcriptional, epigenetic, and physiological integration during development
Q63938025The role of DNA methylation in human trophoblast differentiation
Q28590982The transcription factor TCFAP2C/AP-2gamma cooperates with CDX2 to maintain trophectoderm formation
Q26829478Tracking the intermediate stages of epithelial-mesenchymal transition in epithelial stem cells and cancer
Q30529634Transcription factor AP-2γ is a core regulator of tight junction biogenesis and cavity formation during mouse early embryogenesis.
Q34506096Transcriptional regulators of the trophoblast lineage in mammals with hemochorial placentation
Q27005860Troika of the mouse blastocyst: lineage segregation and stem cells
Q38074629Trophoblast differentiation of human embryonic stem cells
Q42623660Trophoblast stem cells
Q37590510Understanding the molecular circuitry of cell lineage specification in the early mouse embryo
Q36570125What Is Trophoblast? A Combination of Criteria Define Human First-Trimester Trophoblast
Q42919552Wolf Reik: Inheritance beyond DNA. Interview by Nicole Lebrasseur
Q33954976X chromosome inactivation and differentiation occur readily in ES cells doubly-deficient for macroH2A1 and macroH2A2.

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