Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers

scientific article published on 11 January 2010

Genetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1017/S1461145709991167
P698PubMed publication ID20059804
P5875ResearchGate publication ID40897626

P50authorGustavo TureckiQ3121397
P2093author name stringLaura M Fiori
P2860cites workPartial deletion of both the spermine synthase gene and the Pex gene in the X-linked hypophosphatemic, gyro (Gy) mouseQ48488450
Polyamines can protect against ischemia-induced nerve cell death in gerbil forebrainQ48783158
Natural history of suicidal behaviors in a population-based sample of young adults.Q50884947
New SMS mutation leads to a striking reduction in spermine synthase protein function and a severe form of Snyder-Robinson X-linked recessive mental retardation syndrome.Q51889768
Is violent method of suicide a behavioral marker of lifetime aggression?Q51928388
A missense mutation, p.V132G, in the X-linked spermine synthase gene (SMS) causes Snyder-Robinson syndrome.Q55510851
Linkage disequilibrium analysis of childhood-onset spinal muscular atrophy (SMA) in the French-Canadian populationQ72017400
Implication of SSAT by gene expression and genetic variation in suicide and major depressionQ82150935
Promoter-wide hypermethylation of the ribosomal RNA gene promoter in the suicide brainQ21144321
Identification and characterization of a novel flavin-containing spermine oxidase of mammalian cell originQ24534758
Cloning and characterization of multiple human polyamine oxidase splice variants that code for isoenzymes with different biochemical characteristicsQ24534962
The International HapMap ProjectQ27860695
High-resolution profiling of histone methylations in the human genomeQ27860906
Haploview: analysis and visualization of LD and haplotype mapsQ27860955
Aminopropyltransferases: function, structure and geneticsQ28293007
Mouse spermine oxidase gene splice variants. Nuclear subcellular localization of a novel active isoformQ28586857
Decarboxylases involved in polyamine biosynthesis and their inactivation by nitric oxideQ28646259
PolyaminesQ29615154
GAD1 mRNA expression and DNA methylation in prefrontal cortex of subjects with schizophreniaQ33295394
X-linked spermine synthase gene (SMS) defect: the first polyamine deficiency syndromeQ34265101
Acetylderivatives as intermediates in polyamine catabolismQ34281808
Histone modifications dictate specific biological readoutsQ34949462
Introns in gene evolutionQ35179945
Overview of the brain polyamine-stress-response: regulation, development, and modulation by lithium and role in cell survivalQ35545548
Polyamines and apoptosis.Q36275690
A chromatin assay for human brain tissueQ36982465
Cytosine methylation in gene-silencing mechanismsQ37300448
Through the looking glass: examining neuroanatomical evidence for cellular alterations in major depressionQ37398246
Patterns of gene expression in the limbic system of suicides with and without major depressionQ38303798
Altered expression of genes involved in ATP biosynthesis and GABAergic neurotransmission in the ventral prefrontal cortex of suicides with and without major depression.Q38515241
Identification and characterization of spermidine/spermine N1-acetyltransferase promoter variants in suicide completersQ39850642
Widespread monoallelic expression on human autosomesQ40050793
Induction of human spermine oxidase SMO(PAOh1) is regulated at the levels of new mRNA synthesis, mRNA stabilization and newly synthesized proteinQ41980845
The impact of spermine synthase (SMS) mutations on brain morphologyQ42122757
Characterization of transgenic mice with widespread overexpression of spermine synthase.Q42807006
Histone methylation and decreased expression of TrkB.T1 in orbital frontal cortex of suicide completersQ43288457
Methylation and QTDT analysis of the 5-HT2A receptor 102C allele: analysis of suicidality in major psychosisQ45113068
Genetic and epigenetic analysis of SSAT gene dysregulation in suicidal behaviorQ46124084
Profiling brain expression of the spermidine/spermine N1-acetyltransferase 1 (SAT1) gene in suicideQ46157854
Alternative splicing, methylation state, and expression profile of tropomyosin-related kinase B in the frontal cortex of suicide completersQ46174413
Evolutionary diversification in polyamine biosynthesis.Q46463665
GABAA receptor promoter hypermethylation in suicide brain: implications for the involvement of epigenetic processesQ46474456
Chromatin alterations associated with down-regulated metabolic gene expression in the prefrontal cortex of subjects with schizophreniaQ46630222
Aberrant DNA methylation associated with bipolar disorder identified from discordant monozygotic twinsQ48182410
Brain S-adenosylmethionine decarboxylase activity is increased in Alzheimer's diseaseQ48285186
P433issue6
P921main subjectsuicideQ10737
P304page(s)725-736
P577publication date2010-01-11
P1433published inThe International Journal of NeuropsychopharmacologyQ7742309
P1476titleGenetic and epigenetic influences on expression of spermine synthase and spermine oxidase in suicide completers
P478volume13

Reverse relations

cites work (P2860)
Q38245264An overview of the neurobiology of suicidal behaviors as one meta-system.
Q33770054Association of polyaminergic loci with anxiety, mood disorders, and attempted suicide
Q38022064Epigenetic modifications associated with suicide and common mood and anxiety disorders: a systematic review of the literature
Q38183424Epigenetic studies of suicidal behavior
Q37656733Epigenetics and suicidal behavior research pathways
Q28074917Genetic Association Studies of Suicidal Behavior: A Review of the Past 10 Years, Progress, Limitations, and Future Directions
Q48933889Global gene expression profiling of the polyamine system in suicide completers
Q46443602Glutamatergic GRIN2B and polyaminergic ODC1 genes in suicide attempts: associations and gene-environment interactions with childhood/adolescent physical assault.
Q90451243Interactions between Macrophages and Cyst-Lining Epithelial Cells Promote Kidney Cyst Growth in Pkd1-Deficient Mice
Q38083578Neurobiology of suicide: do biomarkers exist?
Q45793667Regulatory role of miRNAs in polyamine gene expression in the prefrontal cortex of depressed suicide completers
Q93112033Spermidine/spermine-N1-acetyltransferase ablation impacts tauopathy-induced polyamine stress response
Q38138118Suicide and the polyamine system
Q37639841The Life Span Model of Suicide and Its Neurobiological Foundation
Q34545232Understanding the epigenetic basis of sex differences in depression.

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