Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models

scientific article published on 14 December 2009

Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1017/S0007114509992741
P698PubMed publication ID20003617
P5875ResearchGate publication ID40681482

P50authorCinta BladéQ56826370
Alba MaciàQ39050965
Maria-José MotilvaQ39050998
P2093author name stringAida Serra
Maria-Paz Romero
Lluís Arola
Josep Valls
P2860cites workStability of polyphenols in chokeberry (Aronia melanocarpa) subjected to in vitro gastric and pancreatic digestionQ57759919
Comparison of Five In Vitro Digestion Models To Study the Bioaccessibility of Soil ContaminantsQ59836468
A trimer plus a dimer-gallate reproduce the bioactivity described for an extract of grape seed procyanidinsQ60197882
Catechins are bioavailable in men and women drinking black tea throughout the dayQ73953862
Bioavailability of catechins from tea: the effect of milkQ74661436
Accumulation of (-)-epicatechin metabolites in rat plasma after oral administration and distribution of conjugation enzymes in rat tissuesQ74739778
Formation of antioxidants from (-)-epigallocatechin gallate in mild alkaline fluids, such as authentic intestinal juice and mouse plasmaQ80991588
Polyphenols: food sources and bioavailabilityQ29618132
Dietary intake and bioavailability of polyphenolsQ33985768
The absorption, metabolism and excretion of flavan-3-ols and procyanidins following the ingestion of a grape seed extract by rats.Q34444736
Metabolism of Tea Flavonoids in the Gastrointestinal TractQ35547532
A review of the health effects of green tea catechins in in vivo animal modelsQ35966610
Validation of green tea polyphenol biomarkers in a phase II human intervention trialQ36477355
Biomarkers of the intake of dietary polyphenols: strengths, limitations and application in nutrition researchQ36897513
In vivo, in vitro, and in silico studies of Cu/Zn-superoxide dismutase regulation by molecules in grape seed procyanidin extract.Q39868865
Dietary procyanidins lower triglyceride levels signaling through the nuclear receptor small heterodimer partner.Q39948244
Impact of orally administered microcapsules on gastrointestinal microbial flora: in-vitro investigation using computer controlled dynamic human gastrointestinal modelQ40183172
Physiochemical and physiological mechanisms for the effects of food on drug absorption: the role of lipids and pH.Q41364364
Analysis of (+)-catechin, (-)-epicatechin and their 3'- and 4'-O-methylated analogs. A comparison of sensitive methods.Q41668329
(+)-Catechin in human plasma after ingestion of a single serving of reconstituted red wineQ41711597
Epicatechin in human plasma: in vivo determination and effect of chocolate consumption on plasma oxidation statusQ41751565
The metabolism and excretion of (+)-[14C]cyanidanol-3 in man following oral administrationQ42253646
Grape-seed derived procyanidins interfere with adipogenesis of 3T3-L1 cells at the onset of differentiationQ42814276
Grape seed-derived procyanidins have an antihyperglycemic effect in streptozotocin-induced diabetic rats and insulinomimetic activity in insulin-sensitive cell linesQ42827011
Stability of the flavan-3-ols epicatechin and catechin and related dimeric procyanidins derived from cocoaQ43470633
Decomposition of cocoa procyanidins in the gastric milieuQ43518365
Addition of milk does not affect the absorption of flavonols from tea in man.Q43551468
Food effects on the absorption and pharmacokinetics of cocoa flavanolsQ43674165
Absorption and urinary excretion of (-)-epicatechin after administration of different levels of cocoa powder or (-)-epicatechin in ratsQ43823046
Cocoa procyanidins are stable during gastric transit in humansQ43957369
Absorption and urinary excretion of procyanidin B2 [epicatechin-(4beta-8)-epicatechin] in ratsQ44043006
Glucuronidation and sulfation of the tea flavonoid (-)-epicatechin by the human and rat enzymesQ44068577
Procyanidin dimer B2 [epicatechin-(4beta-8)-epicatechin] in human plasma after the consumption of a flavanol-rich cocoaQ44152984
Obtention and characterization of phenolic extracts from different cocoa sourcesQ44298033
Glucuronides of tea catechins: enzymology of biosynthesis and biological activitiesQ44365485
Procyanidin B1 is detected in human serum after intake of proanthocyanidin-rich grape seed extractQ44496634
Metabolism of dietary procyanidins in ratsQ44615943
Effect of fat content on the digestibility and bioaccessibility of cocoa polyphenol by an in vitro digestion model.Q45078300
Grape seed proanthocyanidins correct dyslipidemia associated with a high-fat diet in rats and repress genes controlling lipogenesis and VLDL assembling in liver.Q45937715
Determination of procyanidins and their metabolites in plasma samples by improved liquid chromatography-tandem mass spectrometryQ46078286
Grape-seed procyanidins prevent low-grade inflammation by modulating cytokine expression in rats fed a high-fat dietQ46500697
Ethanol and polyphenolic free wine matrix stimulate the differentiation of human intestinal Caco-2 cells. Influence of their association with a procyanidin-rich grape seed extractQ46584100
Effects of tea polyphenols on emulsification of olive oil in a small intestine model systemQ46967840
Fermentation by gut microbiota cultured in a simulator of the human intestinal microbial ecosystem is improved by supplementing a soygerm powderQ49072453
(+)-Catechin is more bioavailable than (−)-catechin: Relevance to the bioavailability of catechin from cocoaQ54510484
P433issue7
P407language of work or nameEnglishQ1860
P921main subjectbioavailabilityQ461809
P304page(s)944-952
P577publication date2009-12-14
P1433published inBritish Journal of NutritionQ4970206
P1476titleBioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models
P478volume103

Reverse relations

cites work (P2860)
Q50847602A grape seed extract increases active glucagon-like peptide-1 levels after an oral glucose load in rats.
Q38715901Antidiabetic actions of cocoa flavanols
Q28071627At the interface of antioxidant signalling and cellular function: Key polyphenol effects
Q57703567Bioavailability of procyanidin dimers and trimers and matrix food effects in in vitro and in vivo models – CORRIGENDUM
Q42858652Cacao liquor procyanidin extract improves glucose tolerance by enhancing GLUT4 translocation and glucose uptake in skeletal muscle
Q42642866Cancer Chemopreventive Potential of Procyanidin
Q93065442Changes in bioavailability of sour cherry (Prunus cerasus L.) phenolics and anthocyanins when consumed with dairy food matrices
Q50870646Chitosan crosslinked microparticles with encapsulated polyphenols: Water sorption and release properties.
Q34904117Chronic administration of proanthocyanidins or docosahexaenoic acid reverses the increase of miR-33a and miR-122 in dyslipidemic obese rats.
Q46415212Chronic supplementation with dietary proanthocyanidins protects from diet-induced intestinal alterations in obese rats
Q43453177Cinnamtannin A2, a tetrameric procyanidin, increases GLP-1 and insulin secretion in mice
Q41078964Cocoa procyanidins with different degrees of polymerization possess distinct activities in models of colonic inflammation
Q92402004Corticotropin-releasing hormone is significantly upregulated in the mouse paraventricular nucleus following a single oral dose of cinnamtannin A2 as an (-)-epicatechin tetramer
Q43224144Dietary proanthocyanidins modulate BMAL1 acetylation, Nampt expression and NAD levels in rat liver
Q48331687Dietary proanthocyanidins modulate melatonin levels in plasma and the expression pattern of clock genes in the hypothalamus of rats
Q44528968Distribution of grape seed flavanols and their metabolites in pregnant rats and their fetuses
Q48917384Distribution of procyanidins and their metabolites in rat plasma and tissues after an acute intake of hazelnut extract.
Q43494984Distribution of procyanidins and their metabolites in rat plasma and tissues in relation to ingestion of procyanidin-enriched or procyanidin-rich cocoa creams.
Q58877916Dried Pears: Phytochemicals and Potential Health Effects
Q26748878Effect of Cocoa and Its Flavonoids on Biomarkers of Inflammation: Studies of Cell Culture, Animals and Humans
Q92582305Effect of karwanda (Carissa congesta Wight) and sugar addition on physicochemical characteristics of ash gourd (Benincasa hispida) and bottle gourd (Langenaria siceraria) based beverages
Q64061287Effect of α-Glucosylation on the Stability, Antioxidant Properties, Toxicity, and Neuroprotective Activity of (-)-Epigallocatechin Gallate
Q38525666Effects of flavanols on the enteroendocrine system: Repercussions on food intake
Q91965615Flavanol Polymerization Is a Superior Predictor of α-Glucosidase Inhibitory Activity Compared to Flavanol or Total Polyphenol Concentrations in Cocoas Prepared by Variations in Controlled Fermentation and Roasting of the Same Raw Cocoa Beans
Q61696501Flavanol metabolites distribute in visceral adipose depots after a long-term intake of grape seed proanthocyanidin extract in rats
Q39369527Food processing strategies to enhance phenolic compounds bioaccessibility and bioavailability in plant-based foods.
Q39044810Gallic acid is an active component for the anticarcinogenic action of grape seed procyanidins in pancreatic cancer cells
Q36556736Grape Seed Procyanidin Extract Improves Insulin Production but Enhances Bax Protein Expression in Cafeteria-Treated Male Rats
Q49964428Grape and wine polymeric polyphenols: Their importance in enology
Q43182959Grape seed and tea extracts and catechin 3-gallates are potent inhibitors of α-amylase and α-glucosidase activity
Q54351148Grape seed extract supplementation attenuates the heat stress-induced responses of jejunum epithelial cells in Simmental × Qinchuan steers.
Q46959352Grape seed proanthocyanidin extract improves the hepatic glutathione metabolism in obese Zucker rats
Q92447626Health-Promoting Properties of Proanthocyanidins for Intestinal Dysfunction
Q102388865In silico studies evidenced the role of structurally diverse plant secondary metabolites in reducing SARS-CoV-2 pathogenesis
Q38156269Interaction of plant phenols with food macronutrients: characterisation and nutritional-physiological consequences
Q47908815Interactions between cell wall polysaccharides and polyphenols
Q38770951Mechanistic insight into nuclear receptor-mediated regulation of bile acid metabolism and lipid homeostasis by grape seed procyanidin extract (GSPE).
Q39534684Polyphenolic extract of lotus root (edible rhizome of Nelumbo nucifera) alleviates hepatic steatosis in obese diabetic db/db mice
Q38991608Polyphenols Beyond Barriers: A Glimpse into the Brain.
Q50527121Polyphenols prevent lipid abnormalities and arterial dysfunction in hamsters on a high-fat diet: a comparative study of red grape and white persimmon wines.
Q47190068Possible mechanisms of postprandial physiological alterations following flavan 3-ol ingestion
Q55069884Proanthocyanidins against Oxidative Stress: From Molecular Mechanisms to Clinical Applications.
Q31037878Proanthocyanidins modulate microRNA expression in human HepG2 cells
Q47763450Procyanidin A2 in the Australian plant Alectryon oleifolius has anthelmintic activity against equine cyathostomins in vitro.
Q46287091Procyanidin B2 Protects Neurons from Oxidative, Nitrosative, and Excitotoxic Stress
Q50523722Procyanidin B2 induces Nrf2 translocation and glutathione S-transferase P1 expression via ERKs and p38-MAPK pathways and protect human colonic cells against oxidative stress.
Q38941884Procyanidin B2 inhibits inflammasome-mediated IL-1β production in lipopolysaccharide-stimulated macrophages.
Q28729755Procyanidin B3 prevents articular cartilage degeneration and heterotopic cartilage formation in a mouse surgical osteoarthritis model
Q36123745Procyanidin Promotes Translocation of Glucose Transporter 4 in Muscle of Mice through Activation of Insulin and AMPK Signaling Pathways
Q36639446Procyanidins alleviates morphine tolerance by inhibiting activation of NLRP3 inflammasome in microglia
Q38005202Procyanidins improve some disrupted glucose homoeostatic situations: an analysis of doses and treatments according to different animal models
Q47713949Proposed mechanisms of the effects of proanthocyanidins on glucose homeostasis.
Q61812588Role of Intestinal Microbiota in the Bioavailability and Physiological Functions of Dietary Polyphenols
Q38351137Roles of proanthocyanidin rich extracts in obesity.
Q38758118Subchronic treatment with grape-seed phenolics inhibits ghrelin production despite a short-term stimulation of ghrelin secretion produced by bitter-sensing flavanols.
Q38712995The absorption, distribution, metabolism and excretion of procyanidins.
Q47947039The effect of grape seed extract on the pharmacokinetics of dextromethorphan in healthy volunteers.
Q36285113Wine Flavonoids in Health and Disease Prevention

Search more.