Rapid liquid chromatography/tandem mass spectrometer (LCMS) method for clozapine and its metabolite N-desmethyl clozapine (norclozapine) in human serum

scientific article published in January 2009

Rapid liquid chromatography/tandem mass spectrometer (LCMS) method for clozapine and its metabolite N-desmethyl clozapine (norclozapine) in human serum is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/JCLA.20345
P932PMC publication ID6649014
P698PubMed publication ID19927349

P2093author name stringL V Rao
G M Vallaro
M L Snyder
P2860cites workSimultaneous determination of clozapine, norclozapine and clozapine-N-oxide in human plasma by high-performance liquid chromatography with ultraviolet detectionQ30687115
Simultaneous determination of clozapine and its N-desmethyl and N-oxide metabolites in plasma by liquid chromatography/electrospray tandem mass spectrometry and its application to plasma level monitoring in schizophrenic patientsQ33423496
Clozapine for the treatment-resistant schizophrenic. A double-blind comparison with chlorpromazineQ34048732
The assay of clozapine and N-desmethylclozapine in human plasma by high-performance liquid chromatographyQ34122803
Human alpha-1-glycoprotein and its interactions with drugsQ34331335
Clinical trial-based cost-effectiveness analyses of antipsychotic use.Q36675837
Measurement of clozapine and norclozapine in plasma/serum by high performance liquid chromatography with ultraviolet detectionQ36702286
Clozapine-induced seizures and EEG changesQ42282305
Simultaneous analysis of clozapine, clomipramine and their metabolites by reversed-phase liquid chromatography.Q43616083
Determination of clozapine and its N-desmethyl metabolite by high-performance liquid chromatography with ultraviolet detectionQ43630883
Simultaneous determination of olanzapine, clozapine and demethylated metabolites in serum by on-line column-switching high-performance liquid chromatography.Q43703592
Determination of clozapine and its N-demethylated metabolite in plasma by use of gas chromatography-mass spectrometry with single ion detectionQ43794493
Relation of blood counts during clozapine treatment to serum concentrations of clozapine and nor-clozapineQ43978248
Direct-injection high performance liquid chromatography ion trap mass spectrometry for the quantitative determination of olanzapine, clozapine and N-desmethylclozapine in human plasmaQ44060212
Simultaneous quantification of citalopram, clozapine, fluoxetine, norfluoxetine, maprotiline, desmethylmaprotiline and trazodone in human serum by HPLC analysis.Q44263492
Effect of post-mortem changes on peripheral and central whole blood and tissue clozapine and norclozapine concentrations in the domestic pig (Sus scrofa)Q44399803
Determination of clozapine and its metabolite, norclozapine in various biological matrices using high-performance liquid chromatographyQ46929746
High throughput therapeutic drug monitoring of clozapine and metabolites in serum by on-line coupling of solid phase extraction with liquid chromatography-mass spectrometryQ46983458
[Determination of clozapine and its N-demethylated metabolite in serum by gas chromatography-mass spectrometry with selected ion monitoring].Q52415439
Simultaneous determination of the antipsychotic drugs levomepromazine and clozapine and their main metabolites in human plasma by a HPLC-UV method with solid-phase extractionQ56995912
Serum concentrations of clozapine determined by nitrogen selective gas chromatographyQ67023481
Clozapine plasma levels determined by high-performance liquid chromatography with ultraviolet detectionQ67931630
Determination of clozapine and its major metabolites in human serum using automated solid-phase extraction and subsequent isocratic high-performance liquid chromatography with ultraviolet detectionQ67982487
Determination of clozapine in human serum by capillary gas chromatographyQ68068344
Rapid and sensitive determination of clozapine in human plasma using high-performance liquid chromatography and amperometric detectionQ69752308
Determination of clozapine and desmethylclozapine in human plasma by high-performance liquid chromatography with ultraviolet detectionQ70624976
Clozapine-induced EEG abnormalities and clinical response to clozapineQ70885169
A rapid gas chromatographic method quantitating clozapine in human plasma or serum for the purpose of therapeutic monitoringQ70940143
Column liquid chromatographic determination of clozapine and N-desmethylclozapine in human serum using solid-phase extractionQ71030625
Solid-phase extraction and high-performance liquid chromatographic analysis of clozapine and norclozapine in human plasmaQ71840605
On-line fully automated determination of clozapine and desmethylclozapine in human serum by solid-phase extraction on exchangeable cartridges and liquid chromatography using a methanol buffer mobile phase on unmodified silicaQ72273028
Determination of clozapine and its major metabolites in human plasma and red blood cells by high-performance liquid chromatography with ultraviolet absorbance detectionQ73230442
Automated determination of clozapine and major metabolites in serum and urineQ73602213
Analysis of clozapine and norclozapine by high-performance liquid chromatographyQ73764505
Assay for quantitation of clozapine and its metabolite N-desmethylclozapine in human plasma by high-performance liquid chromatography with ultraviolet detectionQ73964647
Determination of clozapine, desmethylclozapine and clozapine N-oxide in human plasma by reversed-phase high-performance liquid chromatography with ultraviolet detectionQ77392437
[The determination of clozapine in blood and urine by gas chromatography-mass spectrometry]Q78194233
P433issue6
P921main subjectliquid chromatography-tandem mass spectrometryQ117788892
P304page(s)394-398
P577publication date2009-01-01
P1433published inJournal of Clinical Laboratory AnalysisQ15754724
P1476titleRapid liquid chromatography/tandem mass spectrometer (LCMS) method for clozapine and its metabolite N-desmethyl clozapine (norclozapine) in human serum
P478volume23

Reverse relations

cites work (P2860)
Q45877250Determination of seven selected antipsychotic drugs in human plasma using microextraction in packed sorbent and gas chromatography-tandem mass spectrometry
Q33751539Enhanced disease reduction using clozapine, an atypical antipsychotic agent, and glatiramer acetate combination therapy in experimental autoimmune encephalomyelitis
Q53081839Sensitive quantification of clozapine and its main metabolites norclozapine and clozapine-N-oxide in serum and urine using LC-MS/MS after simple liquid-liquid extraction work-up.

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