Liver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-kappaB signaling pathway

scientific article published in February 2010

Liver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-kappaB signaling pathway is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/HEP.23313
P698PubMed publication ID19918976
P5875ResearchGate publication ID38094789

P50authorYunfei YuanQ40548428
P2093author name stringTao Wang
Fudi Wang
Dong Xie
Xiao-Fan Wang
Jing-Jing Li
Yu-Xiong Feng
Shu-Qun Cheng
Jiang-Sha Zhao
P2860cites workThe Hallmarks of CancerQ221226
Regulated cleavage of a contact-mediated axon repellentQ28144522
Activation of the EphA2 tyrosine kinase stimulates the MAP/ERK kinase signaling cascadeQ28210840
The global health burden of infection-associated cancers in the year 2002Q28290871
Complementary gradients in expression and binding of ELF-1 and Mek4 in development of the topographic retinotectal projection mapQ28295221
Signalling pathways of the TNF superfamily: a double-edged swordQ29616428
Ephrin-B3 ligand promotes glioma invasion through activation of Rac1.Q33256258
Inhibition of protein kinase B/Akt. implications for cancer therapyQ34145575
Differential gene expression of Eph receptors and ephrins in benign human tissues and cancersQ34290211
Tumor necrosis factor (TNF).Q34378376
Eph and ephrin signaling in mammary gland morphogenesis and cancerQ35676256
Nuclear factor-kappaB and liver carcinogenesisQ36241968
Tumor necrosis factor: how to make a killer molecule tumor-specific?Q36264840
Actin turnover is required to prevent axon retraction driven by endogenous actomyosin contractilityQ36324074
Dysregulation of growth factor signaling in human hepatocellular carcinoma.Q36519010
The receptor tyrosine kinase EphB4 is overexpressed in ovarian cancer, provides survival signals and predicts poor outcomeQ36610209
Immunohistochemical studies of intrahepatic tumour necrosis factor alpha in chronic liver diseaseQ37256387
Interplay between EphB4 on tumor cells and vascular ephrin-B2 regulates tumor growthQ37682093
The EphB4 receptor suppresses breast cancer cell tumorigenicity through an Abl-Crk pathwayQ40252238
Rac1 mediates intestinal epithelial cell apoptosis via JNK.Q40263028
EphB4 receptor tyrosine kinase is expressed in bladder cancer and provides signals for cell survival.Q40365399
Ephrin-A1 expression contributes to the malignant characteristics of {alpha}-fetoprotein producing hepatocellular carcinomaQ40423673
EphA2 expression is associated with aggressive features in ovarian carcinomaQ40527994
Invasiveness of breast carcinoma cells and transcript profile: Eph receptors and ephrin ligands as molecular markers of potential diagnostic and prognostic applicationQ40554993
Expression of ephrin-B1 in hepatocellular carcinoma: possible involvement in neovascularization.Q40612267
Tumor necrosis factor alpha production by peripheral blood mononuclear cells of patients with chronic liver diseaseQ44476688
EphA2 receptor tyrosine kinase regulates endothelial cell migration and vascular assembly through phosphoinositide 3-kinase-mediated Rac1 GTPase activation.Q44822101
Activation of the ERK and AKT signalling pathway predicts poor prognosis in hepatocellular carcinoma and ERK activation in cancer tissue is associated with hepatitis C virus infectionQ45399300
The ephrin-A1 ligand and its receptor, EphA2, are expressed during tumor neovascularizationQ46699319
Cellular localization of ephrin-A2, ephrin-A5, and other functional guidance cues underlies retinotopic development across species.Q48539184
Occurrence of portal vein tumor thrombus in hepatocellular carcinoma affects prognosis and survival. A retrospective clinical study of 150 casesQ60339438
Preoperative and postoperative cytokines in patients with cancerQ67491499
Rac1-mediated endocytosis during ephrin-A2- and semaphorin 3A-induced growth cone collapseQ74472748
Hepatocellular carcinomaQ77355684
Role of Rel/NF-kappaB transcription factors in apoptosis of human hepatocellular carcinoma cellsQ78330691
The continuing increase in the incidence of hepatocellular carcinoma in the United States: an updateQ79302506
Akt phosphorylation is a risk factor for early disease recurrence and poor prognosis in hepatocellular carcinomaQ81128776
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectNF-κBQ411114
liver cancerQ623031
P304page(s)535-544
P577publication date2010-02-01
P1433published inHepatologyQ15724398
P1476titleLiver cancer: EphrinA2 promotes tumorigenicity through Rac1/Akt/NF-kappaB signaling pathway
P478volume51

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cites work (P2860)
Q35783568Clinical relevance of Ephs and ephrins in cancer: lessons from breast, colorectal, and lung cancer profiling
Q39644225Connective tissue growth factor enhances the migration of gastric cancer through downregulation of E‐cadherin via the NF‐κB pathway
Q34540458Design, synthesis, and in vitro and in vivo biological studies of a 3'-deoxythymidine conjugate that potentially kills cancer cells selectively
Q40329185Diagnostic and prognostic value of tissue and circulating levels of Ephrin-A2 in prostate cancer
Q21328694Eph receptors and ephrin ligands: important players in angiogenesis and tumor angiogenesis
Q36576644Eph-A2 and Eph-A4 expression in human benign and malignant thyroid lesions: an immunohistochemical study
Q39362601Genotype analysis of tumor-initiating cells expressing CD133 in neuroblastoma
Q45931466Glycolytic reprogramming through PCK2 regulates tumor initiation of prostate cancer cells.
Q50002028Identification of Key Pathways and Genes in the Dynamic Progression of HCC Based on WGCNA.
Q31040344Involvement of EphB/Ephrin-B signaling in axonal survival in mouse experimental glaucoma
Q46219683Long non-coding RNA MALAT-1 overexpression predicts tumor recurrence of hepatocellular carcinoma after liver transplantation
Q34364217Peritumoral small ephrinA5 isoform level predicts the postoperative survival in hepatocellular carcinoma
Q27323196Pseudomonas aeruginosa exotoxin T induces potent cytotoxicity against a variety of murine and human cancer cell lines.
Q27000047Research advances at the Institute for Nutritional Sciences at Shanghai, China
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Q45876952miR-21 Modulates the Immunoregulatory Function of Bone Marrow Mesenchymal Stem Cells Through the PTEN/Akt/TGF-β1 Pathway

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