Adding clopidogrel to aspirin improves outcome in ST-elevation myocardial infarction patients receiving fibrinolytic therapy

scientific article published in December 2005

Adding clopidogrel to aspirin improves outcome in ST-elevation myocardial infarction patients receiving fibrinolytic therapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1586/14737167.5.6.751
P698PubMed publication ID19807617

P2093author name stringMarc S Sabatine
Sean M Donahoe
P2860cites workA Comparison of Recombinant Hirudin with Heparin for the Treatment of Acute Coronary SyndromesQ56945341
ACC/AHA 2004 Guideline Update for Coronary Artery Bypass Graft Surgery: Summary ArticleQ56986928
ACC/AHA Guidelines for the Management of Patients With ST-Elevation Myocardial Infarction—Executive SummaryQ56986933
ACC/AHA Guidelines for Percutaneous Coronary Intervention (Revision of the 1993 PTCA Guidelines)—Executive SummaryQ58975787
The TIMI Risk Score for Unstable Angina/Non–ST Elevation MIQ22252998
Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patientsQ24555072
Central role of the P2Y12 receptor in platelet activationQ24618777
Effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes: observations from the Clopidogrel in Unstable angina to prevent Recurrent Events (CURE) studyQ28165412
Clopidogrel resistance is associated with increased risk of recurrent atherothrombotic events in patients with acute myocardial infarctionQ28168881
Clopidogrel resistance: a new chapter in a fast-moving storyQ28169150
Cost-effectiveness of clopidogrelQ28174908
Trends in treatment and outcomes for acute myocardial infarction: 1975-1995Q28175989
Increased mortality with oral platelet glycoprotein IIb/IIIa antagonists: a meta-analysis of phase III multicenter randomized trialsQ28176219
Randomized comparison of prasugrel (CS-747, LY640315), a novel thienopyridine P2Y12 antagonist, with clopidogrel in percutaneous coronary intervention: results of the Joint Utilization of Medications to Block Platelets Optimally (JUMBO)-TIMI 26 trialQ28181168
Balancing the benefit and risk of oral antiplatelet agents in coronary artery bypass surgeryQ28184971
Comparison of early invasive and conservative strategies in patients with unstable coronary syndromes treated with the glycoprotein IIb/IIIa inhibitor tirofibanQ28185502
Reperfusion therapy for acute myocardial infarction with fibrinolytic therapy or combination reduced fibrinolytic therapy and platelet glycoprotein IIb/IIIa inhibition: the GUSTO V randomised trialQ28185728
Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevationQ28188284
Meta-analysis of randomized and registry comparisons of ticlopidine with clopidogrel after stentingQ28191931
The effect of clopidogrel in combination with aspirin when given before coronary artery bypass graftingQ28193370
Benefit of clopidogrel in patients with acute coronary syndromes without ST-segment elevation in various risk groupsQ28193817
Resistance to aspirin in vitro is associated with increased platelet sensitivity to adenosine diphosphateQ28194108
Early and sustained dual oral antiplatelet therapy following percutaneous coronary intervention: a randomized controlled trialQ28194232
Early and late effects of clopidogrel in patients with acute coronary syndromesQ28195029
Clopidogrel for coronary stenting: response variability, drug resistance, and the effect of pretreatment platelet reactivityQ28196405
Primary angioplasty versus intravenous thrombolytic therapy for acute myocardial infarction: a quantitative review of 23 randomised trialsQ28202129
Long-term cost-effectiveness of clopidogrel given for up to one year in patients with acute coronary syndromes without ST-segment elevationQ28210312
Clopidogrel added to aspirin versus aspirin alone in secondary prevention and high-risk primary prevention: rationale and design of the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trialQ28210890
Benefits and risks of the combination of clopidogrel and aspirin in patients undergoing surgical revascularization for non-ST-elevation acute coronary syndrome: the Clopidogrel in Unstable angina to prevent Recurrent ischemic Events (CURE) TrialQ28211092
Antithrombotic therapy for coronary artery disease: the Seventh ACCP Conference on Antithrombotic and Thrombolytic TherapyQ28213459
Effects of reviparin, a low-molecular-weight heparin, on mortality, reinfarction, and strokes in patients with acute myocardial infarction presenting with ST-segment elevationQ28213755
Variability in response to aspirin: do we understand the clinical relevance?Q28217618
Addition of clopidogrel to aspirin and fibrinolytic therapy for myocardial infarction with ST-segment elevationQ28218789
An international randomized trial comparing four thrombolytic strategies for acute myocardial infarction. The GUSTO investigatorsQ28254763
Intensive versus moderate lipid lowering with statins after acute coronary syndromesQ29619716
A randomised, blinded, trial of clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE). CAPRIE Steering CommitteeQ29620666
Double-blind study of the safety of clopidogrel with and without a loading dose in combination with aspirin compared with ticlopidine in combination with aspirin after coronary stenting : the clopidogrel aspirin stent international cooperative studyQ33333456
A clinical trial comparing three antithrombotic-drug regimens after coronary-artery stenting. Stent Anticoagulation Restenosis Study Investigators.Q33504515
Effect of early intravenous heparin on coronary patency, infarct size, and bleeding complications after alteplase thrombolysis: results of a randomised double blind European Cooperative Study Group trialQ33611581
The pathophysiology of acute coronary syndromesQ33839207
Atorvastatin reduces the ability of clopidogrel to inhibit platelet aggregation: a new drug-drug interactionQ34168972
A randomized comparison of antiplatelet and anticoagulant therapy after the placement of coronary-artery stentsQ34374902
Early thrombolytic treatment in acute myocardial infarction: reappraisal of the golden hourQ34398044
Sudden death due to cardiac arrhythmiasQ34496008
Expert consensus document on the use of antiplatelet agents. The task force on the use of antiplatelet agents in patients with atherosclerotic cardiovascular disease of the European society of cardiologyQ35628214
Pharmacoinvasive therapy: the future of treatment for ST-elevation myocardial infarctionQ35789802
Resistance to clopidogrel: a review of the evidenceQ36101144
Preclinical and clinical studies with selective reversible direct P2Y12 antagonistsQ36106325
The pathogenesis of coronary artery disease and the acute coronary syndromes (1).Q36728740
Vulnerable plaque: pathobiology and clinical implicationsQ38548243
Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiographyQ39237218
Twenty-two year (1975 to 1997) trends in the incidence, in-hospital and long-term case fatality rates from initial Q-wave and non-Q-wave myocardial infarction: a multi-hospital, community-wide perspectiveQ39566715
Variability in platelet responsiveness to clopidogrel among 544 individuals.Q40454244
Coronary Plaque DisruptionQ40459835
The benefits of aspirin in acute myocardial infarction. Still a well-kept secret in the United StatesQ40793928
Cost effectiveness of thrombolytic therapy with tissue plasminogen activator as compared with streptokinase for acute myocardial infarctionQ40985280
Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease?Q41263009
The in vivo pharmacological profile of CS-747, a novel antiplatelet agent with platelet ADP receptor antagonist propertiesQ41906079
A simple risk index for rapid initial triage of patients with ST-elevation myocardial infarction: an InTIME II substudyQ42043575
Effects of reteplase and alteplase on platelet aggregation and major receptor expression during the first 24 hours of acute myocardial infarction treatment. GUSTO-III Investigators. Global Use of Strategies to Open Occluded Coronary ArteriesQ42679152
Analysis of the relative costs and effectiveness of primary angioplasty versus tissue-type plasminogen activator: the Primary Angioplasty in Myocardial Infarction (PAMI) trial. The PAMI Trial InvestigatorsQ43645713
Efficacy and safety of tenecteplase in combination with enoxaparin, abciximab, or unfractionated heparin: the ASSENT-3 randomised trial in acute myocardial infarctionQ43724527
A comparison of reteplase with alteplase for acute myocardial infarctionQ44205469
Lysis of plasminogen activator-resistant platelet-rich coronary artery thrombus with combined bolus injection of recombinant tissue-type plasminogen activator and antiplatelet GPIIb/IIIa antibodyQ44372589
Effect of heparin on coronary arterial patency after thrombolysis with tissue plasminogen activator in acute myocardial infarctionQ45083112
Health and economic benefits of increased beta-blocker use following myocardial infarctionQ46184653
Enoxaparin versus unfractionated heparin as antithrombin therapy in patients receiving fibrinolysis for ST-elevation myocardial infarction. Design and rationale for the Enoxaparin and Thrombolysis Reperfusion for Acute Myocardial Infarction TreatmenQ46450488
The wavefront phenomenon of ischemic cell death. 1. Myocardial infarct size vs duration of coronary occlusion in dogsQ47325541
Clinical and angiographic correlates and outcomes of suboptimal coronary flow inpatients with acute myocardial infarction undergoing primary percutaneous coronary intervention.Q51792124
Differential sensitivity of erythrocyte-rich and platelet-rich arterial thrombi to lysis with recombinant tissue-type plasminogen activator. A possible explanation for resistance to coronary thrombolysis.Q54357272
ACC/AHA Guideline Update for the Management of Patients With Unstable Angina and Non-ST-Segment Elevation Myocardial Infarction--2002: Summary Article: A Report of the American College of Cardiology/American Heart Association Task Force on Practice GQ55889587
Abciximab as Adjunctive Therapy to Reperfusion in Acute ST-Segment Elevation Myocardial InfarctionQ56944163
Single-bolus tenecteplase compared with front-loaded alteplase in acute myocardial infarction: the ASSENT-2 double-blind randomised trialQ56944998
P433issue6
P921main subjectmyocardial infarctionQ12152
aspirinQ18216
clopidogrelQ410237
P304page(s)751-761
P577publication date2005-12-01
P1433published inExpert Review of Pharmacoeconomics & Outcomes ResearchQ15734522
P1476titleAdding clopidogrel to aspirin improves outcome in ST-elevation myocardial infarction patients receiving fibrinolytic therapy
P478volume5

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cites work (P2860)
Q38065124Comparing newer oral anti-platelets prasugrel and ticagrelor in reduction of ischemic events-evidence from a network meta-analysis.
Q36237726Efficacy and Safety of Novel Oral P2Y12 Receptor Inhibitors in Patients With ST-Segment Elevation Myocardial Infarction Undergoing PCI: A Systematic Review and Meta-Analysis.

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