Denosumab: a promising drug for the prevention and treatment of osteoporosis

scientific article published in July 2006

Denosumab: a promising drug for the prevention and treatment of osteoporosis is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2217/17455057.2.4.517
P8608Fatcat IDrelease_ngkmdcxy55b3leqtxv45swzsyu
P698PubMed publication ID19803959

P2093author name stringE Michael Lewiecki
P2860cites workOsteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
RANK is essential for osteoclast and lymph node developmentQ24598872
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcificationQ24603266
Regulation of vascular calcification by osteoclast regulatory factors RANKL and osteoprotegerinQ28295204
Denosumab in postmenopausal women with low bone mineral densityQ28298728
The long and the short of bone therapyQ28298737
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesisQ28589430
Osteoclast differentiation and activationQ29547556
Drugs used to treat osteoporosis: the critical need for a uniform nomenclature based on their action on bone remodelingQ34384039
Perspective. How many women have osteoporosis?Q35437028
Clinical implications of the osteoprotegerin/RANKL/RANK system for bone and vascular diseases.Q35848843
The bone quality framework: determinants of bone strength and their interrelationships, and implications for osteoporosis managementQ36069258
Osteoprotegerin and RANKL regulate bone resorption, density, geometry and strengthQ36269835
The role of the immune system in the pathophysiology of osteoporosisQ36324969
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Osteoprotegerin overexpression by breast cancer cells enhances orthotopic and osseous tumor growth and contrasts with that delivered therapeutically.Q40296427
Regulation of cancer cell migration and bone metastasis by RANKL.Q40298349
How many women have osteoporosis now?Q40528035
Bone mineral density measurement and treatment for osteoporosis in older individuals with fractures: a gap in evidence-based practice guideline implementationQ40556337
Drug therapy for vertebral fractures in osteoporosis: evidence that decreases in bone turnover and increases in bone mass both determine antifracture efficacyQ41087577
The effect of a single dose of osteoprotegerin in postmenopausal womenQ43520860
Compliance with drug therapies for the treatment and prevention of osteoporosisQ44256311
A phase I study of AMGN-0007, a recombinant osteoprotegerin construct, in patients with multiple myeloma or breast carcinoma related bone metastasesQ44291815
Compliance with pharmacologic therapy for osteoporosisQ44593075
OPG and PTH-(1-34) have additive effects on bone density and mechanical strength in osteopenic ovariectomized ratsQ46099755
A single-dose placebo-controlled study of AMG 162, a fully human monoclonal antibody to RANKL, in postmenopausal womenQ46133598
Opposite bone remodeling effects of teriparatide and alendronate in increasing bone massQ46641001
A study of the biological receptor activator of nuclear factor-kappaB ligand inhibitor, denosumab, in patients with multiple myeloma or bone metastases from breast cancerQ46952812
The impact of compliance with osteoporosis therapy on fracture rates in actual practiceQ49211514
Osteoclast differentiation factor (ODF) induces osteoclast-like cell formation in human peripheral blood mononuclear cell cultures.Q54137269
P433issue4
P921main subjectosteoporosisQ165328
P304page(s)517-525
P577publication date2006-07-01
P1433published inWomen's HealthQ15762155
P1476titleDenosumab: a promising drug for the prevention and treatment of osteoporosis
P478volume2