Inactivation of the infralimbic but not the prelimbic cortex impairs consolidation and retrieval of fear extinction

scientific article published on 25 August 2009

Inactivation of the infralimbic but not the prelimbic cortex impairs consolidation and retrieval of fear extinction is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/LM.1474609
P698PubMed publication ID19706835
P5875ResearchGate publication ID26766906

P50authorVincent LaurentQ43162670
P2093author name stringR Frederick Westbrook
P433issue9
P304page(s)520-529
P577publication date2009-08-25
P1433published inLearning and MemoryQ15765923
P1476titleInactivation of the infralimbic but not the prelimbic cortex impairs consolidation and retrieval of fear extinction
P478volume16

Reverse relations

cites work (P2860)
Q92519412A Focus on the Functions of Area 25
Q24634963A time-dependent role of midline thalamic nuclei in the retrieval of fear memory.
Q27687716A unifying model of the role of the infralimbic cortex in extinction and habits
Q34310202Activation of the infralimbic cortex in a fear context enhances extinction learning
Q42786065Activity in prelimbic cortex subserves fear memory reconsolidation over time.
Q42120042Acute nicotine enhances spontaneous recovery of contextual fear and changes c-fos early gene expression in infralimbic cortex, hippocampus, and amygdala
Q34068917Alterations in reward, fear and safety cue discrimination after inactivation of the rat prelimbic and infralimbic cortices
Q53401887Altered excitability and local connectivity of mPFC-PAG neurons in a mouse model of neuropathic pain.
Q64890002Altering gain of the infralimbic-to-accumbens shell circuit alters economically dissociable decision-making algorithms.
Q92736517Amygdala Reward Neurons Form and Store Fear Extinction Memory
Q33881804Behavioral Effects of Systemic, Infralimbic and Prelimbic Injections of a Serotonin 5-HT2A Antagonist in Carioca High- and Low-Conditioned Freezing Rats
Q27001253Behavioral and neurobiological mechanisms of extinction in Pavlovian and instrumental learning
Q50525587Blocking Synaptic Removal of GluA2-Containing AMPA Receptors Prevents the Natural Forgetting of Long-Term Memories.
Q48163828Brain-derived neurotrophic factor genotype impacts the prenatal cocaine-induced mouse phenotype
Q36141153Changes in expression of c-Fos protein following cocaine-cue extinction learning
Q34494000Clarifying the role of the rostral dmPFC/dACC in fear/anxiety: learning, appraisal or expression?
Q91747948Common neurocircuitry mediating drug and fear relapse in preclinical models
Q54960423Complex housing causes a robust increase in dendritic complexity and spine density of medial prefrontal cortical neurons.
Q38757215Deep Brain Stimulation in Animal Models of Fear, Anxiety, and Posttraumatic Stress Disorder
Q30514335Deep brain stimulation of the ventral striatum enhances extinction of conditioned fear
Q37080190Deep brain stimulation of the ventral striatum increases BDNF in the fear extinction circuit.
Q96690839Different methods of fear reduction are supported by distinct cortical substrates
Q27307744Different neural circuitry is involved in physiological and psychological stress-induced PTSD-like "nightmares" in rats
Q48112675Differential involvement of the medial prefrontal cortex across variants of contextual fear conditioning
Q30497715Dissociable roles of prelimbic and infralimbic cortices, ventral hippocampus, and basolateral amygdala in the expression and extinction of conditioned fear
Q36059897Dissociation of the Role of Infralimbic Cortex in Learning and Consolidation of Extinction of Recent and Remote Aversion Memory.
Q30377834Distinct ensembles of medial prefrontal cortex neurons are activated by threatening stimuli that elicit excitation vs. inhibition of movement.
Q40048840Distinct roles for the deacetylase domain of HDAC3 in the hippocampus and medial prefrontal cortex in the formation and extinction of memory.
Q57459359Dopamine-dependent prefrontal reactivations explain long-term benefit of fear extinction
Q39004183Dysfunction in amygdala-prefrontal plasticity and extinction-resistant avoidance: A model for anxiety disorder vulnerability
Q36901973Effect of D-cycloserine in conjunction with fear extinction training on extracellular signal-regulated kinase activation in the medial prefrontal cortex and amygdala in rat.
Q37486797Emergence in extinction of enhanced and persistent responding to ambiguous aversive cues is associated with high MAOA activity in the prelimbic cortex.
Q39273747Emotional learning, stress, and development: An ever-changing landscape shaped by early-life experience
Q24629806Emotional processing in anterior cingulate and medial prefrontal cortex
Q50066459Enhanced operant extinction and prefrontal excitability in a mouse model of Angelman syndrome
Q30380912Enhancement of fear extinction with deep brain stimulation: evidence for medial orbitofrontal involvement
Q30394729Epigenetics and memory: causes, consequences and treatments for post-traumatic stress disorder and addiction
Q37432212Estradiol shifts interactions between the infralimbic cortex and central amygdala to enhance fear extinction memory in female rats
Q95832226Excitation of prefrontal cortical neurons during conditioning enhances fear memory formation
Q50480653Extinction and Latent Inhibition Involve a Similar Form of Inhibitory Learning that is Stored in and Retrieved from the Infralimbic Cortex.
Q97533560Extinction and drug-induced reinstatement of cocaine seeking following self-administration or conditioned place preference in adolescent and adult rats
Q30625337FAAH genetic variation enhances fronto-amygdala function in mouse and human
Q36173118Fear Expression Suppresses Medial Prefrontal Cortical Firing in Rats
Q28254365Fear extinction as a model for translational neuroscience: ten years of progress
Q30435673Fear learning and memory across adolescent development: Hormones and Behavior Special Issue: Puberty and Adolescence
Q37607503Functional anatomy of ventromedial prefrontal cortex: implications for mood and anxiety disorders
Q42290422GABA Concentrations in the Anterior Cingulate Cortex Are Associated with Fear Network Function and Fear Recovery in Humans
Q30477927Glutamate receptors in extinction and extinction-based therapies for psychiatric illness
Q37380077Going and stopping: dichotomies in behavioral control by the prefrontal cortex
Q34749779Hippocampal inactivation with TTX impairs long-term spatial memory retrieval and modifies brain metabolic activity.
Q48102794Hippocampus-driven feed-forward inhibition of the prefrontal cortex mediates relapse of extinguished fear
Q28286179Immunohistochemical analyses of long-term extinction of conditioned fear in adolescent rats
Q100307229Infralimbic cortex controls fear memory generalization and susceptibility to extinction during consolidation
Q61136751Infralimbic cortex is required for learning alternatives to prelimbic promoted associations through reciprocal connectivity
Q91887416Infralimbic prefrontal cortex structural and functional connectivity with the limbic forebrain: a combined viral genetic and optogenetic analysis
Q53429886Inhibitory gain modulation of defense behaviors by zona incerta.
Q26828055Inhibitory networks of the amygdala for emotional memory
Q50464991Ketamine accelerates fear extinction via mTORC1 signaling.
Q91529808Layer- and subregion-specific electrophysiological and morphological changes of the medial prefrontal cortex in a mouse model of neuropathic pain
Q30424268Learned together, extinguished apart: reducing fear to complex stimuli.
Q48463891Low-frequency stimulation depresses the primate anterior-cingulate-cortex and prevents spontaneous recovery of aversive memories.
Q30445778M-Type Potassium Channels Modulate the Intrinsic Excitability of Infralimbic Neurons and Regulate Fear Expression and Extinction
Q28396555Mechanisms to medicines: elucidating neural and molecular substrates of fear extinction to identify novel treatments for anxiety disorders
Q47787266Medial prefrontal cannabinoid CB1 receptors modulate consolidation and extinction of cocaine-associated memory in mice
Q38054599Medial prefrontal cortex: multiple roles in fear and extinction
Q40139959Mild Traumatic Brain Injury Reduces Spine Density of Projection Neurons in the Medial Prefrontal Cortex and Impairs Extinction of Contextual Fear Memory
Q50574306Mineralocorticoid receptors in the ventral hippocampus are involved in extinction memory in rats.
Q37863149Modulation of fear memory by retrieval and extinction: a clue for memory deconsolidation
Q47931276Molecular and Cellular Effects of Traumatic Stress: Implications for PTSD.
Q24604822NMDA receptors and fear extinction: implications for cognitive behavioral therapy
Q33627434Neocortical Tet3-mediated accumulation of 5-hydroxymethylcytosine promotes rapid behavioral adaptation
Q30356625Neural activity in the prelimbic and infralimbic cortices of freely moving rats during social interaction: Effect of isolation rearing
Q33906630Neural structures mediating expression and extinction of platform-mediated avoidance.
Q39442644Neural systems mediating the inhibition of cocaine-seeking behaviors
Q34477053Neuronal circuits for fear and anxiety.
Q40058614On and Off switches in the brain
Q27328579Optogenetic stimulation of infralimbic PFC reproduces ketamine's rapid and sustained antidepressant actions.
Q35171317PKMζ maintains drug reward and aversion memory in the basolateral amygdala and extinction memory in the infralimbic cortex
Q36281272Paradoxical enhancement of fear extinction memory and synaptic plasticity by inhibition of the histone acetyltransferase p300
Q92536075Pathway specific activation of ventral hippocampal cells projecting to the prelimbic cortex diminishes fear renewal
Q35851816Persistent active avoidance correlates with activity in prelimbic cortex and ventral striatum
Q45871397Persistent histone modifications at the BDNF and Cdk-5 promoters following extinction of nicotine-seeking in rats
Q27006437Pharmacology of cognitive enhancers for exposure-based therapy of fear, anxiety and trauma-related disorders
Q30476116Plastic synaptic networks of the amygdala for the acquisition, expression, and extinction of conditioned fear
Q36400690Plasticity of Fear and Safety Neurons of the Amygdala in Response to Fear Extinction
Q47631672Prefrontal Cortex Deep Brain Stimulation Improves Fear and Anxiety-Like Behavior and Reduces Basolateral Amygdala Activity in a Preclinical Model of Posttraumatic Stress Disorder
Q37715147Prefrontal control of fear: more than just extinction.
Q35989378Prefrontal dopamine regulates fear reinstatement through the downregulation of extinction circuits
Q30578917Prefrontal entrainment of amygdala activity signals safety in learned fear and innate anxiety
Q41145060Prefrontal infralimbic cortex mediates competition between excitation and inhibition of body movements during pavlovian fear conditioning
Q36201622Prefrontal inputs to the amygdala instruct fear extinction memory formation.
Q34608692Prelimbic and infralimbic neurons signal distinct aspects of appetitive instrumental behavior
Q33664683Prelimbic cortical BDNF is required for memory of learned fear but not extinction or innate fear
Q64217985Protective effects of elevated anandamide on stress and fear-related behaviors: translational evidence from humans and mice
Q30419931Psychological and neural mechanisms of experimental extinction: a selective review
Q27308009Rapid antidepressant actions of scopolamine: Role of medial prefrontal cortex and M1-subtype muscarinic acetylcholine receptors
Q58602772Rapid reacquisition of contextual fear following extinction in mice: effects of amount of extinction, acute ethanol withdrawal, and ethanol intoxication
Q35146447Rescue of impaired fear extinction and normalization of cortico-amygdala circuit dysfunction in a genetic mouse model by dietary zinc restriction
Q42789642Resting state low-frequency fluctuations in prefrontal cortex reflect degrees of harm avoidance and novelty seeking: an exploratory NIRS study
Q28257827Revisiting the role of infralimbic cortex in fear extinction with optogenetics
Q36545380Role of medial prefrontal cortex Narp in the extinction of morphine conditioned place preference
Q37876896Role of the basolateral amygdala and NMDA receptors in higher-order conditioned fear
Q30466738Seeking a spotless mind: extinction, deconsolidation, and erasure of fear memory
Q30359974Selective Control of Fear Expression by Optogenetic Manipulation of Infralimbic Cortex after Extinction.
Q36775163Sex differences in anxiety disorders: Interactions between fear, stress, and gonadal hormones
Q33875417Sleep-Dependent Oscillatory Synchronization: A Role in Fear Memory Consolidation
Q36719882Specific Targeting of the Basolateral Amygdala to Projectionally Defined Pyramidal Neurons in Prelimbic and Infralimbic Cortex.
Q30366954Stress and Fear Extinction.
Q26776203The Role of the Medial Prefrontal Cortex in the Conditioning and Extinction of Fear
Q38082742The amygdala and medial prefrontal cortex: partners in the fear circuit
Q42879305The basolateral amygdala is critical for the acquisition and extinction of associations between a neutral stimulus and a learned danger signal but not between two neutral stimuli.
Q43034784The contribution of medial prefrontal cortical regions to conditioned inhibition
Q48960097The orbitofrontal cortex as part of a hierarchical neural system mediating choice between two good options.
Q60680360The prefrontal cortical endocannabinoid system modulates fear-pain interactions in a subregion-specific manner
Q30453175The prelimbic cortex is critical for context-dependent fear expression
Q89357284The role of the basolateral amygdala and infralimbic cortex in (re)learning extinction
Q30417829The role of the medial prefrontal cortex in regulating social familiarity-induced anxiolysis.
Q90662716The rostroventral part of the thalamic reticular nucleus modulates fear extinction
Q43548263The ventromedial prefrontal cortex in a model of traumatic stress: fear inhibition or contextual processing?
Q57302141WHEN SCIENTIFIC PARADIGMS LEAD TO TUNNEL VISION: LESSONS FROM THE STUDY OF FEAR
Q92217485Why we need nonhuman primates to study the role of ventromedial prefrontal cortex in the regulation of threat- and reward-elicited responses
Q102388946c-Fos expression following context conditioning and deep brain stimulation in the bed nucleus of the stria terminalis in rats
Q36303815p300/CBP-associated factor selectively regulates the extinction of conditioned fear

Search more.