5-Hydroxytryptophan activates colonic myenteric neurons and propulsive motor function through 5-HT4 receptors in conscious mice

scientific article published on 21 September 2006

5-Hydroxytryptophan activates colonic myenteric neurons and propulsive motor function through 5-HT4 receptors in conscious mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPGI.00289.2006
P698PubMed publication ID16990446
P5875ResearchGate publication ID240012941

P50authorYvette TachéQ66317833
P2093author name stringWang L
Kimura H
Martínez V
P2860cites work5-HT1A and 5-HT4 receptors mediate inhibition and facilitation of fast synaptic transmission in enteric neuronsQ46458731
5-HT4 receptors located on cholinergic nerves in human colon circular muscleQ46509742
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Muscarinic and 5-HT4 receptors participate in the regulation of the frequency of spontaneous contractions of the longitudinal muscle in rat distal colonQ46694427
Enterochromaffin cell hyperplasia and decreased serotonin transporter in a mouse model of postinfectious bowel dysfunctionQ46841580
Localization of the 5-HT(4) receptor in the human and the guinea pig colonQ46899152
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Projections and chemistry of Dogiel type II neurons in the mouse colon.Q49300330
Relative importance of enterochromaffin cell hyperplasia, anxiety, and depression in postinfectious IBS.Q51010528
Postprandial plasma 5-hydroxytryptamine in diarrhoea predominant irritable bowel syndrome: a pilot studyQ28379389
Selective stimulation of colonic transit by the benzofuran 5HT4 agonist, prucalopride, in healthy humansQ33844909
Immunohistochemical localization of tryptophan hydroxylase in the human and rat gastrointestinal tractsQ33869202
Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndromeQ33960506
Functions of peripheral 5-hydroxytryptamine receptors, especially 5-hydroxytryptamine4 receptor, in gastrointestinal motilityQ34012427
Review article: intestinal serotonin signalling in irritable bowel syndromeQ34566461
Review article: serotonin receptors and transporters -- roles in normal and abnormal gastrointestinal motilityQ34650033
Increased defecation during stress or after 5-hydroxytryptophan: selective inhibition by the 5-HT(4) receptor antagonist, SB-207266.Q35042318
Role of serotonin in the pathophysiology of the irritable bowel syndromeQ35047066
On the concentration of 5-hydroxytryptamine in mammalian enterochromaffin cells and its release by reserpineQ36263473
Serotonin excites neurons in the human submucous plexus via 5-HT3 receptorsQ40424072
Fos: an immediate-early transcription factor in neuronsQ40541836
Molecular defects in mucosal serotonin content and decreased serotonin reuptake transporter in ulcerative colitis and irritable bowel syndrome.Q42462847
Participation of 5-HT3, 5-HT4, and nicotinic receptors in the peristaltic reflex of guinea pig distal colonQ42552167
RS 39604: a potent, selective and orally active 5‐HT4 receptor antagonistQ42708186
An improved in vitro bioassay for the study of 5-HT(4) receptors in the human isolated large intestinal circular muscleQ43263780
Synthesis and pharmacological evaluation of benzamide derivatives as selective 5-HT(4) receptor agonistsQ43320504
Increased defaecation caused by 5-HT4 receptor activation in the mouse.Q43330465
SB-207266: 5-HT4 receptor antagonism in human isolated gut and prevention of 5-HT-evoked sensitization of peristalsis and increased defaecation in animal modelsQ43333573
Increased gastric cholinergic activity evoked by 5-hydroxy-L-tryptophan in the rat.Q43529367
Intracisternal TRH analog induces Fos expression in gastric myenteric neurons and glia in conscious ratsQ43568323
Acute cold exposure induces vagally mediated Fos expression in gastric myenteric neurons in conscious ratsQ43669444
Peripheral CRF activates myenteric neurons in the proximal colon through CRF(1) receptor in conscious ratsQ43964302
The involvement of 5-HT3 and 5-HT4 receptors in two models of gastrointestinal transit in miceQ44048968
5-HT4 receptor enhances the propulsive power of the peristaltic reflex in the rat distal colonQ44096926
Effects of extrinsic autonomic inputs on expression of c-Fos immunoreactivity in myenteric neurons of the guinea pig distal colonQ44182549
Effects of mosapride citrate, a 5-HT4 receptor agonist, on colonic motility in conscious guinea pigsQ44261598
Differential actions of peripheral corticotropin-releasing factor (CRF), urocortin II, and urocortin III on gastric emptying and colonic transit in mice: role of CRF receptor subtypes 1 and 2.Q44280590
Neuronal location of 5-hydroxytryptamine3 receptor-like immunoreactivity in the rat colonQ44345611
Neurotransmitters mediating the intestinal peristaltic reflex in the mouseQ44579407
Correlation of electrophysiological and morphological characteristics of enteric neurons in the mouse colon.Q44675810
Presynaptic modulation of cholinergic and non-cholinergic fast synaptic transmission in the myenteric plexus of guinea pig ileumQ44937809
Evidence for a 5-HT4 receptor pathway mediating chloride secretion in the rat distal colonQ45087654
Distinct 5-HT receptors mediate the peristaltic reflex induced by mucosal stimuli in human and guinea pig intestineQ45100964
Nuclear Fos immunoreactivity in guinea pig myenteric neurons following activation of motor activityQ46220970
Interleukin-1beta activates specific populations of enteric neurons and enteric glia in the guinea pig ileum and colonQ46271526
Central vagal stimulation activates enteric cholinergic neurons in the stomach and VIP neurons in the duodenum in conscious ratsQ46289019
Immunohistochemical demonstration of choline acetyltransferase of a peripheral type (pChAT) in the enteric nervous system of ratsQ46293857
Peripheral corticotropin-releasing factor induces diarrhea in rats: role of CRF1 receptor in fecal watery excretionQ46374304
Abnormalities of 5-hydroxytryptamine metabolism in irritable bowel syndromeQ46431252
P433issue1
P304page(s)G419-28
P577publication date2006-09-21
P1433published inAmerican Journal of Physiology - Gastrointestinal and Liver PhysiologyQ15765756
P1476title5-Hydroxytryptophan activates colonic myenteric neurons and propulsive motor function through 5-HT4 receptors in conscious mice
P478volume292

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cites work (P2860)
Q463989365-HT4 receptors facilitate cholinergic neurotransmission throughout the murine gastrointestinal tract.
Q64108363A Novel Antiserum Against a Predicted Human Peripheral Choline Acetyltransferase (hpChAT) for Labeling Neuronal Structures in Human Colon
Q40698638A novel role for the metabotropic glutamate receptor-7: modulation of faecal water content and colonic electrolyte transport in the mouse
Q37271198Ablation of least shrew central neurokinin NK1 receptors reduces GR73632-induced vomiting
Q46649469An evaluation of the non-invasive faecal pellet assessment method as an early drug discovery screen for gastrointestinal liability
Q37604072Ca2+ responses in enteric glia are mediated by connexin-43 hemichannels and modulate colonic transit in mice
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Q41847481Central somatostatin receptor 1 activation reverses acute stress-related alterations of gastric and colonic motor function in mice
Q37227044Cholinergic giant migrating contractions in conscious mouse colon assessed by using a novel noninvasive solid-state manometry method: modulation by stressors.
Q40156283Deletion of P2X2 and P2X3 receptor subunits does not alter motility of the mouse colon
Q43364082Free fatty acid receptor 3 activation suppresses neurogenic motility in rat proximal colon
Q91793597Gastrointestinal neuroimmune disruption in a mouse model of Gulf War illness
Q37016812Mice overexpressing wild-type human alpha-synuclein display alterations in colonic myenteric ganglia and defecation
Q36788491Modulation of the adaptive response to stress by brain activation of selective somatostatin receptor subtypes
Q51399510New method of manometric measurement of gastroduodenal motility in conscious mice: effects of ghrelin and Y2 depletion.
Q33304561Peripheral corticotropin releasing factor (CRF) and a novel CRF1 receptor agonist, stressin1-A activate CRF1 receptor expressing cholinergic and nitrergic myenteric neurons selectively in the colon of conscious rats
Q33589013Peripheral peptide YY inhibits propulsive colonic motor function through Y2 receptor in conscious mice

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