Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study

scientific article published in November 2000

Relationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study is …
instance of (P31):
scholarly articleQ13442814

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P698PubMed publication ID11097226

P2093author name stringLeppert M
Slattery ML
Robertson M
Curtin K
Samowitz WS
Schaffer D
P433issue11
P407language of work or nameEnglishQ1860
P304page(s)1193-1197
P577publication date2000-11-01
P1433published inCancer Epidemiology, Biomarkers & PreventionQ326334
P1476titleRelationship of Ki-ras mutations in colon cancers to tumor location, stage, and survival: a population-based study
P478volume9

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cites work (P2860)
Q53069742A chromatin modifier genetic screen identifies SIRT2 as a modulator of response to targeted therapies through the regulation of MEK kinase activity.
Q37283757A comparison of colon and rectal somatic DNA alterations
Q36089983A comparison of three methods for detecting KRAS mutations in formalin-fixed colorectal cancer specimens
Q35584153A review of the most promising biomarkers in colorectal cancer: one step closer to targeted therapy
Q35402251A specific KRAS codon 13 mutation is an independent predictor for colorectal cancer metachronous distant metastases
Q37593331Adrenomedullin is a therapeutic target in colorectal cancer
Q34007796Alcohol consumption and rectal tumor mutations and epigenetic changes
Q53490424An Unusual Combination: KRAS and BRAF Co-mutated Metastatic Colorectal Cancer.
Q45834924An appraisal of lymph node ratio in colon and rectal cancer: not one size fits all.
Q42583248Analytical performance of a PCR assay for the detection of KRAS mutations (codons 12/13 and 61) in formalin-fixed paraffin-embedded tissue samples of colorectal carcinoma
Q89843964Association Between Molecular Subtypes of Colorectal Tumors and Patient Survival, Based on Pooled Analysis of 7 International Studies
Q34759064Association between molecular subtypes of colorectal cancer and patient survival
Q36229011Association between proto-oncogene mutations and clinicopathologic characteristics and overall survival in colorectal cancer in East Azerbaijan, Iran.
Q41862336Association of epidermal growth factor receptor and K-Ras mutations with smoking history in non-small cell lung cancer patients
Q34617200Associations between genetic variation in RUNX1, RUNX2, RUNX3, MAPK1 and eIF4E and riskof colon and rectal cancer: additional support for a TGF-β-signaling pathway
Q36540553Associations of Ki-ras proto-oncogene mutation and p53 gene overexpression in sporadic colorectal adenomas with demographic and clinicopathologic characteristics
Q33740175Associations of anthropometric factors with KRAS and BRAF mutation status of primary colorectal cancer in men and women: a cohort study
Q34517338BRAF V600E mutation and KRAS codon 13 mutations predict poor survival in Chinese colorectal cancer patients
Q37056074BRAF mutation predicts for poor outcomes after metastasectomy in patients with metastatic colorectal cancer.
Q54325213BRAF-mutated, microsatellite-stable adenocarcinoma of the proximal colon: an aggressive adenocarcinoma with poor survival, mucinous differentiation, and adverse morphologic features.
Q35677900C/EBP-β-activated microRNA-223 promotes tumour growth through targeting RASA1 in human colorectal cancer
Q33727871Characterization of rare transforming KRAS mutations in sporadic colorectal cancer.
Q33959887Clinical relevance of KRAS in human cancers
Q34591262Clinical significance of K-ras and BRAF mutations in Chinese colorectal cancer patients
Q34010171Colon tumor mutations and epigenetic changes associated with genetic polymorphism: insight into disease pathways
Q27003134Colorectal Cancer Biomarkers: Where Are We Now?
Q35579056Colorectal carcinomas with KRAS codon 12 mutation are associated with more advanced tumor stages
Q51033072Colorectal liver metastases are more often super wild type. Toward treatment based on metastatic site genotyping?
Q92838608Comparison of clinicopathological features and KRAS gene mutation of left-sided and right-sided colon cancers
Q34371471Comparison of neuroendocrine differentiation and KRAS/NRAS/BRAF/PIK3CA/TP53 mutation status in primary and metastatic colorectal cancer.
Q34598203Computational analysis of KRAS mutations: implications for different effects on the KRAS p.G12D and p.G13D mutations
Q36487348Correlation between Gene Variants, Signaling Pathways, and Efficacy of Chemotherapy Drugs against Colon Cancers
Q33541307Dietary, lifestyle and clinicopathological factors associated with BRAF and K-ras mutations arising in distinct subsets of colorectal cancers in the EPIC Norfolk study
Q35652713Distinct Clinicopathological Patterns of Mismatch Repair Status in Colorectal Cancer Stratified by KRAS Mutations
Q35773077Distinct gene expression profiles of proximal and distal colorectal cancer: implications for cytotoxic and targeted therapy.
Q57056971Dual-specificity phosphatase 6 deletion protects the colonic epithelium against inflammation and promotes both proliferation and tumorigenesis
Q36790406EGFR Expression and KRAS and BRAF Mutational Status in Intestinal-Type Sinonasal Adenocarcinoma
Q34627605EGFR Signaling in Colorectal Carcinoma
Q92219419Exploring the Pharmacological Mechanism of the Herb Pair "HuangLian-GanJiang" against Colorectal Cancer Based on Network Pharmacology
Q28087333Extended RAS testing in metastatic colorectal cancer-Refining the predictive molecular biomarkers
Q35584550External quality assessment for KRAS testing is needed: setup of a European program and report of the first joined regional quality assessment rounds
Q35024163Frequent mutations of KRAS in addition to BRAF in colorectal serrated adenocarcinoma.
Q36610632Genetic and epigenetic alterations of Ras signalling pathway in colorectal neoplasia: analysis based on tumour clinicopathological features
Q37523207Genetic prognostic and predictive markers in colorectal cancer
Q35627924Genetic variability in EGFR, Src and HER2 and risk of colorectal adenoma and cancer.
Q53277819Genetic variability in IL23R and risk of colorectal adenoma and colorectal cancer.
Q35588474Genetic variation in C-reactive protein in relation to colon and rectal cancer risk and survival
Q34572197Genetic variation in RPS6KA1, RPS6KA2, RPS6KB1, RPS6KB2, and PDK1 and risk of colon or rectal cancer
Q34094993Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.
Q30503444Genetic variation in bone morphogenetic protein and colon and rectal cancer
Q30498922Genetic variation in the TGF-β signaling pathway and colon and rectal cancer risk
Q36334742Genetic variation in the transforming growth factor-β signaling pathway and survival after diagnosis with colon and rectal cancer
Q35229101Global impact of KRAS mutation patterns in FOLFOX treated metastatic colorectal cancer
Q36469155Glutathione peroxidase tagSNPs: associations with rectal cancer but not with colon cancer
Q36113663High sensitivity isoelectric focusing to establish a signaling biomarker for the diagnosis of human colorectal cancer
Q36069872Identification of a common variant with potential pleiotropic effect on risk of inflammatory bowel disease and colorectal cancer
Q36775133Impact of KRAS Mutation Status on Outcomes in Metastatic Colon Cancer Patients without Anti-Epidermal Growth Factor Receptor Therapy
Q37352557Impact of KRAS, BRAF, PIK3CA, TP53 status and intraindividual mutation heterogeneity on outcome after liver resection for colorectal cancer metastases
Q39094258Implication of K-ras and p53 in colorectal cancer carcinogenesis in Tunisian population cohort
Q37563971Implications for KRAS status and EGFR-targeted therapies in metastatic CRC.
Q24629358Increased risk of colon cancer associated with a genetic polymorphism of SMAD7
Q38761790Infrequently expressed miRNAs in colorectal cancer tissue and tumor molecular phenotype
Q35479013Interferon-signaling pathway: associations with colon and rectal cancer risk and subsequent survival
Q36315711Interleukin genes and associations with colon and rectal cancer risk and overall survival
Q33703112K-RAS mutation profile in Puerto Rican patients with colorectal cancer: trends from April 2009 to January 2011.
Q42922888K-Ras and MSI: potential markers of both patient prognosis and treatment efficacy
Q48097655KRAS Exon 2 Mutations as Prognostic Indicators in Advanced Colorectal Cancer in Clinical Practice: A Mono-Institutional Study
Q39186065KRAS allel-specific activity of sunitinib in an isogenic disease model of colorectal cancer.
Q35045790KRAS and BRAF gene mutations and DNA mismatch repair status in Chinese colorectal carcinoma patients
Q41136513KRAS as a predictor of poor prognosis and benefit from postoperative FOLFOX chemotherapy in patients with stage II and III colorectal cancer
Q27852414KRAS as prognostic biomarker in metastatic colorectal cancer patients treated with bevacizumab: a pooled analysis of 12 published trials
Q33693309KRAS codon 12 and 13 mutations in relation to disease-free survival in BRAF-wild-type stage III colon cancers from an adjuvant chemotherapy trial (N0147 alliance).
Q37709323KRAS exon 2 codon 13 mutation is associated with a better prognosis than codon 12 mutation following lung metastasectomy in colorectal cancer
Q35233954KRAS mutation and microsatellite instability: two genetic markers of early tumor development that influence the prognosis of colorectal cancer
Q39642103KRAS mutation detection and prognostic potential in sporadic colorectal cancer using high-resolution melting analysis
Q27851532KRAS mutation in stage III colon cancer and clinical outcome following intergroup trial CALGB 89803
Q37273361KRAS mutation testing for predicting response to anti-EGFR therapy for colorectal carcinoma: proposal for an European quality assurance program.
Q89845681KRAS mutations by digital PCR in circulating tumor cells isolated from the mesenteric vein are associated with residual disease and overall survival in resected colorectal cancer patients
Q36097103KRAS status and clinical outcome in metastatic colorectal cancer patients treated with first-line FOLFOX chemotherapy
Q51701640KRAS testing and its importance in colorectal cancer.
Q36889656KRAS-mutation status in relation to colorectal cancer survival: the joint impact of correlated tumour markers
Q38765961KSR1 and EPHB4 Regulate Myc and PGC1β To Promote Survival of Human Colon Tumors
Q34585656Krüppel-like factor 5 mediates cellular transformation during oncogenic KRAS-induced intestinal tumorigenesis
Q42777241Left and right sided large bowel cancer
Q30528832MAP kinase genes and colon and rectal cancer
Q33746903Microarray applications in cancer research
Q33954707Microsatellite instability and survival in rectal cancer
Q35737549Molecular analysis of colorectal tumors within a diverse patient cohort at a single institution
Q30807030Molecular lesions in colorectal cancer: impact on prognosis? Original data and review of the literature
Q34665492Molecular markers identify subtypes of stage III colon cancer associated with patient outcomes
Q24620628Molecular pathological epidemiology of colorectal neoplasia: an emerging transdisciplinary and interdisciplinary field
Q37878380Multiple mutations in the Kras gene in colorectal cancer: review of the literature with two case reports
Q52633432Mutation analysis of adenomas and carcinomas of the colon: Early and late drivers.
Q33412122Mutation detection by real-time PCR: a simple, robust and highly selective method
Q90241844Mutation profiling of cancer drivers in Brazilian colorectal cancer
Q21261222Mutations in APC, CTNNB1 and K-ras genes and expression of hMLH1 in sporadic colorectal carcinomas from the Netherlands Cohort Study
Q54591533Mutations in BRAF correlate with poor survival of colorectal cancers in Chinese population.
Q49679318Mutations in KRAS codon 12 predict poor survival in Chinese patients with metastatic colorectal cancer
Q33534522Mutations in epidermal growth factor receptor and K-ras in Chinese patients with colorectal cancer
Q50679391Mutations of KRAS and PIK3CA as independent predictors of distant metastases in colorectal cancer.
Q30368810Novel KRAS gene mutations in sporadic colorectal cancer
Q37241845Oncogene Mutations in Colorectal Polyps Identified in the Norwegian Colorectal Cancer Prevention (NORCCAP) Screening Study
Q37091527Oncogenetic tree model of somatic mutations and DNA methylation in colon tumors.
Q34749595Oncogenic K-ras promotes early carcinogenesis in the mouse proximal colon
Q36050773PTEN mRNA expression is less pronounced in left- than right-sided colon cancer: a retrospective observational study
Q50080288Patterns and the Occurrence of KRAS Mutations in Metastatic Colorectal Cancers-a Study from Indian Regional Cancer Centre
Q33401352Phase I pharmacokinetic and pharmacodynamic study of cetuximab, irinotecan and sorafenib in advanced colorectal cancer
Q37051209Phase II study of everolimus in patients with metastatic colorectal adenocarcinoma previously treated with bevacizumab-, fluoropyrimidine-, oxaliplatin-, and irinotecan-based regimens
Q37172368Phospholipase A2G1B polymorphisms and risk of colorectal neoplasia.
Q37107712Prognostic role of KRAS mutations in Sardinian patients with colorectal carcinoma
Q35012132Prognostic value of KRAS and BRAF mutations in curatively resected colorectal cancer
Q38600228Prognostic value of KRAS codon 13 gene mutation for overall survival in colorectal cancer: Direct and indirect comparison meta-analysis.
Q42139232RAS mutations vary between lesions in synchronous primary colorectal cancer: testing only one lesion is not sufficient to guide anti-EGFR treatment decisions.
Q98771157Relevance of Pharmacogenomics and Multidisciplinary Management in a Young-Elderly Patient With KRAS Mutant Colorectal Cancer Treated With First-Line Aflibercept-Containing Chemotherapy
Q36121090Right-sided colon cancer and left-sided colorectal cancers respond differently to cetuximab
Q33599123Role of RAS mutation status as a prognostic factor for patients with advanced colorectal cancer treated with first-line chemotherapy based on fluoropyrimidines and oxaliplatin, with or without bevavizumab: A retrospective analysis
Q38104294Role of targeted agents in metastatic colorectal cancer.
Q40773360Sensitive and specific detection of K-ras mutations in colon tumors by short oligonucleotide mass analysis
Q37355802Sex differences in the prognostic significance of KRAS codons 12 and 13, and BRAF mutations in colorectal cancer: a cohort study
Q39139086Specific mutations in KRAS codon 12 are associated with worse overall survival in patients with advanced and recurrent colorectal cancer
Q36761405Specific mutations in KRAS codons 12 and 13, and patient prognosis in 1075 BRAF wild-type colorectal cancers
Q37023898Statistical strategies to improve the efficiency of molecular studies of colorectal cancer prognosis
Q36185880TERT's role in colorectal carcinogenesis
Q34616409The role of oncogenes in gastrointestinal cancer
Q42111689Tumour gene expression predicts response to cetuximab in patients with KRAS wild-type metastatic colorectal cancer
Q35576313Variation in the CYP19A1 gene and risk of colon and rectal cancer
Q34622865Worse prognosis of KRAS c.35 G > A mutant metastatic colorectal cancer (MCRC) patients treated with intensive triplet chemotherapy plus bevacizumab (FIr-B/FOx)

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