Metabolic Engineering of Escherichia coli for Producing Astaxanthin as the Predominant Carotenoid

scientific article published on 22 September 2017

Metabolic Engineering of Escherichia coli for Producing Astaxanthin as the Predominant Carotenoid is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3390/MD15100296
P8608Fatcat IDrelease_xgpbtq3y5zb5fdwppk64srszhi
P932PMC publication ID5666404
P698PubMed publication ID28937591

P2093author name stringQian Lu
Jian-Zhong Liu
Yi-Fan Bu
P2860cites workHighly efficient biosynthesis of astaxanthin in Saccharomyces cerevisiae by integration and tuning of algal crtZ and bkt.Q53187505
Characterization of two beta-carotene ketolases, CrtO and CrtW, by complementation analysis in Escherichia coli.Q54443649
Metabolic engineering of Escherichia coli to produce zeaxanthinQ86382031
Engineering of a plasmid-free Escherichia coli strain for improved in vivo biosynthesis of astaxanthinQ21246033
Tight regulation, modulation, and high-level expression by vectors containing the arabinose PBAD promoterQ27860697
Comparative analysis of β-carotene hydroxylase genes for astaxanthin biosynthesisQ28267239
In vitro characterization of astaxanthin biosynthetic enzymesQ34417410
Enzymic confirmation of reactions involved in routes to astaxanthin formation, elucidated using a direct substrate in vitro assayQ34462204
Metabolic engineering towards biotechnological production of carotenoids in microorganismsQ34968158
Characterization of cyanobacterial beta-carotene ketolase and hydroxylase genes in Escherichia coli, and their application for astaxanthin biosynthesisQ34975583
Astaxanthin, a carotenoid with potential in human health and nutritionQ36430644
Conversion of beta-carotene into astaxanthin: Two separate enzymes or a bifunctional hydroxylase-ketolase protein?Q37090534
Codon influence on protein expression in E. coli correlates with mRNA levelsQ37319891
Genome mining of astaxanthin biosynthetic genes from Sphingomonas sp. ATCC 55669 for heterologous overproduction in Escherichia coliQ37340198
Carotenoid β-ring hydroxylase and ketolase from marine bacteria-promiscuous enzymes for synthesizing functional xanthophyllsQ37889647
Pathway engineering strategies for production of beneficial carotenoids in microbial hostsQ38001337
Engineering a beta-carotene ketolase for astaxanthin productionQ38310870
Spanning high-dimensional expression space using ribosome-binding site combinatoricsQ40366148
Functional characterization of various algal carotenoid ketolases reveals that ketolating zeaxanthin efficiently is essential for high production of astaxanthin in transgenic Arabidopsis.Q42115113
Production of the Marine Carotenoid Astaxanthin by Metabolically Engineered Corynebacterium glutamicumQ42401892
Mutational and functional analysis of the beta-carotene ketolase involved in the production of canthaxanthin and astaxanthinQ43153535
Characterization of cyanobacterial carotenoid ketolase CrtW and hydroxylase CrtR by complementation analysis in Escherichia coliQ46262382
Alleviation of metabolic bottleneck by combinatorial engineering enhanced astaxanthin synthesis in Saccharomyces cerevisiaeQ46405526
Characterization of beta-carotene ketolases, CrtW, from marine bacteria by complementation analysis in Escherichia coliQ46592963
Dynamic control of the mevalonate pathway expression for improved zeaxanthin production in Escherichia coli and comparative proteome analysisQ47853604
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue10
P921main subjectEscherichia coliQ25419
astaxanthinQ413740
P577publication date2017-09-22
P1433published inMarine DrugsQ2122804
P1476titleMetabolic Engineering of Escherichia coli for Producing Astaxanthin as the Predominant Carotenoid
P478volume15

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cites work (P2860)
Q89017686Assessment of Expression Cassettes and Culture Media for Different Escherichia coli Strains to Produce Astaxanthin
Q58716172Astaxanthin overproduction in yeast by strain engineering and new gene target uncovering
Q91660310Construction of Escherichia coli cell factories for crocin biosynthesis
Q54202653Construction of an alternative glycerol-utilization pathway for improved β-carotene production in Escherichia coli.
Q92375851Effects of Methanol on Carotenoids as Well as Biomass and Fatty Acid Biosynthesis in Schizochytrium limacinum B4D1
Q99416154Engineering CrtW and CrtZ for improving biosynthesis of astaxanthin in Escherichia coli
Q55515608Food Modulation Controls Astaxanthin Accumulation in Eggs of the Sea Urchin Arbacia lixula.
Q90872731Metabolic engineering of Escherichia coli for high-level astaxanthin production with high productivity

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