The R100Q mutation of the GABA(A) alpha(6) receptor subunit may contribute to voluntary aversion to ethanol in the sNP rat line

scientific article published in March 2001

The R100Q mutation of the GABA(A) alpha(6) receptor subunit may contribute to voluntary aversion to ethanol in the sNP rat line is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0169-328X(01)00003-1
P698PubMed publication ID11245930

P50authorLuca PaniQ19721647
P2093author name stringGessa GL
Porcella A
Saba L
Pistis M
Colombo G
Congeddu E
Peis M
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Molecular and electrophysiological characterization of a allelic variant of the rat alpha 6 GABAA receptor subunitQ33187442
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Different sensitivities to ethanol in alcohol-preferring and -nonpreferring ratsQ49021773
The alpha 1 and alpha 6 subunits can coexist in the same cerebellar GABAA receptor maintaining their individual benzodiazepine-binding specificities.Q49156390
Benzodiazepines act on GABAA receptors via two distinct and separable mechanisms.Q50720910
Association between variants at the GABAAbeta2, GABAAalpha6 and GABAAgamma2 gene cluster and alcohol dependence in a Scottish population.Q52172907
Association analysis of sequence variants of GABA(A) alpha6, beta2, and gamma2 gene cluster and alcohol dependence.Q52979588
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Ethyl Alcohol Consumption: Valid Measurement in Albino RatsQ95784940
P433issue2
P304page(s)263-270
P577publication date2001-03-01
P1433published inMolecular Brain ResearchQ6895939
P1476titleThe R100Q mutation of the GABA(A) alpha(6) receptor subunit may contribute to voluntary aversion to ethanol in the sNP rat line
P478volume87

Reverse relations

cites work (P2860)
Q34974161A reinforcing circuit action of extrasynaptic GABAA receptor modulators on cerebellar granule cell inhibition
Q33787183Alcohol-induced motor impairment caused by increased extrasynaptic GABA(A) receptor activity
Q22241964Alcoholism: A Systems Approach From Molecular Physiology to Addictive Behavior
Q49228452Allosteric Modulation of αβδ GABAA Receptors.
Q30447847Animal models for medications development targeting alcohol abuse using selectively bred rat lines: neurobiological and pharmacological validity
Q34216724Basis of the gabamimetic profile of ethanol
Q44371612Characterization of wild-type (R100R) and mutated (Q100Q) GABAA alpha 6 subunit in Sardinian alcohol non-preferring rats (sNP).
Q34749269Drug interactions at GABA(A) receptors
Q22252547Ethanol acts directly on extrasynaptic subtypes of GABAA receptors to increase tonic inhibition
Q34592214From gene to behavior and back again: new perspectives on GABAA receptor subunit selectivity of alcohol actions
Q33781201GABAA receptor subtypes: the "one glass of wine" receptors
Q50178492GABAA receptor: Positive and negative allosteric modulators
Q33761809Low dose acute alcohol effects on GABA A receptor subtypes
Q36830483Modulation of GABAA receptors in cerebellar granule neurons by ethanol: a review of genetic and electrophysiological studies.
Q44318978Molecular characterization of new polymorphisms at the beta2, alpha1, gamma2 GABA(A) receptor subunit genes associated to a rat nonpreferring ethanol phenotype
Q41875469The cerebellar GABAAR α6-R100Q polymorphism alters ligand binding in outbred Sprague-Dawley rats in a similar manner as in selectively bred AT and ANT rats
Q24658287The sigma-receptor antagonist BD-1063 decreases ethanol intake and reinforcement in animal models of excessive drinking

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