Different antagonist binding properties of human and rat histamine H3 receptors

scientific article published in April 2001

Different antagonist binding properties of human and rat histamine H3 receptors is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0960-894X(01)00090-7
P698PubMed publication ID11294398

P50authorWolfgang SipplQ37836608
P2093author name stringStark H
Schwartz JC
Arrang JM
Ligneau X
Schunack W
Ganellin CR
P2860cites workAn alpha-carbon template for the transmembrane helices in the rhodopsin family of G-protein-coupled receptorsQ41633574
General construction pattern of histamine H3-receptor antagonists: change of a paradigmQ46760999
Cloning and cerebral expression of the guinea pig histamine H3 receptor: evidence for two isoformsQ46872768
Therapeutic potential of histamine H3 receptor agonists and antagonists.Q47888475
Development of FUB 181, a selective histamine H3-receptor antagonist of high oral in vivo potency with 4-(omega-(arylalkyloxy)alkyl)-1H-imidazole structureQ48407371
A novel series of (phenoxyalkyl)imidazoles as potent H3-receptor histamine antagonistsQ48917846
[125I]iodoproxyfan and related compounds: a reversible radioligand and novel classes of antagonists with high affinity and selectivity for the histamine H3 receptorQ49057563
Docking of hydrophobic ligands with interaction-based matching algorithms.Q51646570
Novel histamine H(3)-receptor antagonists with carbonyl-substituted 4-(3-(phenoxy)propyl)-1H-imidazole structures like ciproxifan and related compoundsQ73126822
Cloning and functional expression of the human histamine H3 receptorQ22009916
Tick histamine-binding proteins: isolation, cloning, and three-dimensional structureQ27618514
Crystal structure of rhodopsin: A G protein-coupled receptorQ27625972
Stereochemical quality of protein structure coordinatesQ27860874
Relationship between the inhibition constant (K1) and the concentration of inhibitor which causes 50 per cent inhibition (I50) of an enzymatic reactionQ27860958
H3-receptors control histamine release in human brainQ28338958
Distinct pharmacology of rat and human histamine H(3) receptors: role of two amino acids in the third transmembrane domainQ28344970
Auto-inhibition of brain histamine release mediated by a novel class (H3) of histamine receptorQ34249836
Novel carbamates as potent histamine H3 receptor antagonists with high in vitro and oral in vivo activityQ34386365
The histamine H3 receptor and its ligandsQ34483311
Highly potent and selective ligands for histamine H3-receptorsQ34661299
P433issue7
P407language of work or nameEnglishQ1860
P1104number of pages4
P304page(s)951-954
P577publication date2001-04-01
P1433published inBioorganic & Medicinal Chemistry LettersQ2709483
P1476titleDifferent antagonist binding properties of human and rat histamine H3 receptors
P478volume11

Reverse relations

cites work (P2860)
Q404459404-phenoxypiperidines: potent, conformationally restricted, non-imidazole histamine H3 antagonists
Q43489571A new class of diamine-based human histamine H3 receptor antagonists: 4-(aminoalkoxy)benzylamines
Q42020167Comparison of the pharmacological properties of human and rat histamine H3-receptors
Q34144187Differential in vivo effects of H3 receptor ligands in a new mouse dipsogenia model
Q43886066Effects of histamine H(3) receptor ligands GT-2331 and ciproxifan in a repeated acquisition avoidance response in the spontaneously hypertensive rat pup.
Q44672323Evidence of histamine receptors in fish brain using an in vivo [14C]2-deoxyglucose autoradiographic method and an in vitro receptor-binding autoradiographic method
Q58860144Generation of a homology model of the human histamine H3 receptor for ligand docking and pharmacophore-based screening
Q44416588Imidazole derivatives as a novel class of hybrid compounds with inhibitory histamine N-methyltransferase potencies and histamine hH3 receptor affinities
Q26827568International Union of Basic and Clinical Pharmacology. XCVIII. Histamine Receptors
Q39510948Mathematical analysis of the sodium sensitivity of the human histamine H3 receptor
Q44410722Molecular and pharmacological characterization of the mouse histamine H3 receptor
Q40656744Molecular modeling and pharmacological analysis of species-related histamine H(3) receptor heterogeneity
Q37780549Recent advances in histamine H3 receptor antagonists/inverse agonists.
Q45099994Search for histamine H(3) receptor ligands with combined inhibitory potency at histamine N-methyltransferase: omega-piperidinoalkanamine derivatives
Q44693728Synthesis and three-dimensional quantitative structure-activity relationship analysis of H3 receptor antagonists containing a neutral heterocyclic polar group
Q34313795The crystallographic model of rhodopsin and its use in studies of other G protein-coupled receptors

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