Effects of olprinone, a new phosphodiesterase inhibitor, on gastric intramucosal acidosis and systemic inflammatory responses following hypothermic cardiopulmonary bypass

scientific article published in April 2001

Effects of olprinone, a new phosphodiesterase inhibitor, on gastric intramucosal acidosis and systemic inflammatory responses following hypothermic cardiopulmonary bypass is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1034/J.1399-6576.2001.045004427.X
P698PubMed publication ID11300380

P2093author name stringTakahashi S
Akiyoshi K
Irita K
Yamaura K
Taniyama T
P2860cites workPositive inotropic and vasodilator actions of milrinone in patients with severe congestive heart failure. Dose-response relationships and comparison to nitroprussideQ28362454
The effect of selective phosphodiesterase 3 and 4 isoenzyme inhibitors and established anti-asthma drugs on inflammatory cell activationQ28379336
Regulation of macrophage gene expression by pro- and anti-inflammatory cytokinesQ33868159
Gastrointestinal luminal PCO2 tonometry: an update on physiology, methodology and clinical applicationsQ33877372
Perioperative plasma volume expansion reduces the incidence of gut mucosal hypoperfusion during cardiac surgeryQ34293617
Prediction of requirement for, and outcome of, prolonged mechanical ventilation following cardiac surgeryQ39455149
PDE isoenzymes as targets for anti-asthma drugsQ40432650
Associations between intramucosal acidosis in the gut and organ failure.Q40873467
Gastric intramucosal pH. A better predictor of multiorgan dysfunction syndrome and death than oxygen-derived variables in patients with sepsisQ41074980
Gastric intramucosal pH as a therapeutic index of tissue oxygenation in critically ill patientsQ41089036
Does gastric tonometry work? No.Q41137846
Prospective trial of supranormal values of survivors as therapeutic goals in high-risk surgical patients.Q41403952
The inflammatory response to cardiopulmonary bypassQ41480038
Inflammatory response to cardiopulmonary bypass: mechanisms involved and possible therapeutic strategiesQ41604810
The systemic inflammatory response to cardiopulmonary bypass: pathophysiological, therapeutic, and pharmacological considerationsQ41606619
Comparison of gastric intramucosal pH with measures of oxygen transport and consumption in critically ill patientsQ41848063
Gastric tonometry and venous oximetry in cardiac surgery patients.Q42059012
Hemodynamic and clinical benefits with intravenous milrinone in severe chronic heart failure: results of a multicenter study in the United StatesQ44446042
Elevation of cardiac output and oxygen delivery improves outcome in septic shockQ46090707
Interleukin-10 does not mediate the inhibitory effect of PDE-4 inhibitors and other cAMP-elevating drugs on lipopolysaccharide-induced tumors necrosis factor-alpha generation from human peripheral blood monocytes.Q47959852
Effects of temperature and flow rate on regional blood flow and metabolism during cardiopulmonary bypassQ48473645
Milrinone modulates endotoxemia, systemic inflammation, and subsequent acute phase response after cardiopulmonary bypass (CPB).Q51479777
Influence of enoximone on systemic and splanchnic oxygen utilization and endotoxin release following cardiopulmonary bypass.Q51547412
Anti-inflammatory activities of cAMP-elevating agents: enhancement of IL-10 synthesis and concurrent suppression of TNF production.Q51571631
Dopexamine and dopamine in the prevention of low gastric mucosal pH following cardiopulmonary by-pass.Q51590181
Comparison of gastric air tonometry with standard saline tonometry.Q52893918
Systemic inflammatory response syndrome after cardiac operations.Q53987195
Effects of vasoactive drugs on gastric intramucosal pHQ64127276
Sodium bicarbonate administration affects the diagnostic accuracy of gastrointestinal tonometry in acute mesenteric ischemiaQ67493545
Effects of dopamine on T-lymphocyte proliferative responses and serum prolactin concentrations in critically ill patientsQ67599326
Effect of a novel inhibitor of cyclic AMP phosphodiesterase, E-1020, on cytosolic Ca++ level and contraction in vascular smooth muscleQ68279356
Predictive value of the stomach wall pH for complications after cardiac operations: comparison with other monitoringQ70320674
Effects of intracoronary infusion of an inotropic agent, E-1020 (loprinone hydrochloride), on cardiac function: evaluation of left ventricular contractile performance using the end-systolic pressure-volume relationshipQ70789366
Attenuation of cardiopulmonary bypass-derived inflammatory reactions reduces myocardial reperfusion injury in cardiac operationsQ70874116
Hepatic blood flow and right ventricular function during cardiac surgery assessed by transesophageal echocardiographyQ71306931
Effect of dopexamine on calculated low gastric intramucosal pH following valve replacementQ71772962
Gastric mucosal pH does not reflect changes in splanchnic blood flow after cardiac surgeryQ72109123
Dobutamine-induced dissociation between changes in splanchnic blood flow and gastric intramucosal pH after cardiac surgeryQ72159160
Effect of cardiopulmonary bypass on gastrointestinal perfusion and functionQ72781227
Comparison of the effects on arterial-ventricular coupling between phosphodiesterase inhibitor and dobutamine in the diseases human heartQ72842545
Postoperative inflammatory response after autologous and allogeneic blood transfusionQ73747078
P433issue4
P407language of work or nameEnglishQ1860
P304page(s)427-434
P577publication date2001-04-01
P1433published inActa Anaesthesiologica ScandinavicaQ59829
P1476titleEffects of olprinone, a new phosphodiesterase inhibitor, on gastric intramucosal acidosis and systemic inflammatory responses following hypothermic cardiopulmonary bypass
P478volume45

Reverse relations

cites work (P2860)
Q35112320A review of anti-inflammatory strategies in cardiac surgery
Q41820543Cardiopulmonary Bypass, Inflammation and How to Defy it: Focus on Pharmacological Interventions
Q37657841Clinical and molecular genetics of the phosphodiesterases (PDEs).
Q35549429Gastric tonometry guided therapy in critical care patients: a systematic review and meta-analysis
Q35096807Phosphodiesterases as therapeutic targets

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