Pharmacokinetics of pterostilbene in Sprague-Dawley rats: the impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability.

scientific article published on 18 February 2013

Pharmacokinetics of pterostilbene in Sprague-Dawley rats: the impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/MNFR.201200651
P8608Fatcat IDrelease_oslzfpcn5jfnderqrzujl6y7y4
P698PubMed publication ID23417986

P50authorHai-Shu LinQ84929621
P2093author name stringPaul C Ho
Samuel Chao Ming Yeo
P2860cites workPharmacokinetics, oral bioavailability, and metabolic profile of resveratrol and its dimethylether analog, pterostilbene, in ratsQ24597042
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Impact of physiological, physicochemical and biopharmaceutical factors in absorption and metabolism mechanisms on the drug oral bioavailability of rats and humansQ36909306
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Chemopreventive effects of pterostilbene on urethane-induced lung carcinogenesis in mice via the inhibition of EGFR-mediated pathways and the induction of apoptosis and autophagyQ39251116
Pterostilbene ameliorates tumor necrosis factor alpha-induced pancreatitis in vitro.Q39284253
Pterostilbene suppresses benzo[a]pyrene-induced airway remodelingQ39524144
Determination of trans-2,4,3',4',5'-pentamethoxystilbene in rat plasma and its application to a pharmacokinetic study.Q39708919
In vitro evaluation of the cytotoxic, anti-proliferative and anti-oxidant properties of pterostilbene isolated from Pterocarpus marsupiumQ39740180
Pterostilbene from Vitis coignetiae protect H2O2-induced inhibition of gap junctional intercellular communication in rat liver cell lineQ39902648
Pterostilbene suppressed lipopolysaccharide-induced up-expression of iNOS and COX-2 in murine macrophages.Q39957137
Pterostilbene, a natural analogue of resveratrol, potently inhibits 7,12-dimethylbenz[a]anthracene (DMBA)/12-O-tetradecanoylphorbol-13-acetate (TPA)-induced mouse skin carcinogenesisQ42716719
Pterostilbene is more potent than resveratrol in preventing azoxymethane (AOM)-induced colon tumorigenesis via activation of the NF-E2-related factor 2 (Nrf2)-mediated antioxidant signaling pathwayQ42748324
Inhibitory effects of garcinol and pterostilbene on cell proliferation and adipogenesis in 3T3-L1 cellsQ42803142
Pterostilbene inhibits colorectal aberrant crypt foci (ACF) and colon carcinogenesis via suppression of multiple signal transduction pathways in azoxymethane-treated miceQ42948195
Pterostilbene inhibited tumor invasion via suppressing multiple signal transduction pathways in human hepatocellular carcinoma cellsQ43758223
Cancer chemopreventive and antioxidant activities of pterostilbene, a naturally occurring analogue of resveratrolQ44008461
Antineoplastic agents. 465. Structural modification of resveratrol: sodium resverastatin phosphateQ44010079
Dietary administration of high doses of pterostilbene and quercetin to mice is not toxic.Q46085613
Pterostilbene, a new agonist for the peroxisome proliferator-activated receptor alpha-isoform, lowers plasma lipoproteins and cholesterol in hypercholesterolemic hamstersQ46456798
The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrolQ46482181
Effects of resveratrol and its derivatives on lipopolysaccharide-induced microglial activation and their structure-activity relationshipsQ46566686
Low-dose pterostilbene, but not resveratrol, is a potent neuromodulator in aging and Alzheimer's diseaseQ48856453
Preclinical pharmacokinetic evaluation of resveratrol trimethyl ether in sprague-dawley rats: the impacts of aqueous solubility, dose escalation, food and repeated dosing on oral bioavailability.Q51374512
The antioxidant role of pterostilbene in streptozotocin-nicotinamide-induced type 2 diabetes mellitus in Wistar rats.Q51484569
Pterostilbene, an active constituent of blueberries, suppresses aberrant crypt foci formation in the azoxymethane-induced colon carcinogenesis model in rats.Q53338338
Pterostilbene, a natural small-molecular compound, promotes cytoprotective macroautophagy in vascular endothelial cells.Q54490390
Pterostilbene protects vascular endothelial cells against oxidized low-density lipoprotein-induced apoptosis in vitro and in vivoQ57246979
P433issue6
P921main subjectpharmacokineticsQ323936
bioavailabilityQ461809
P304page(s)1015-1025
P577publication date2013-02-18
P1433published inMolecular Nutrition and Food ResearchQ15751861
P1476titlePharmacokinetics of pterostilbene in Sprague-Dawley rats: the impacts of aqueous solubility, fasting, dose escalation, and dosing route on bioavailability
P478volume57

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