scholarly article | Q13442814 |
P356 | DOI | 10.1016/S0891-5849(01)00512-3 |
P698 | PubMed publication ID | 11369504 |
P50 | author | Roger Walz | Q45853164 |
P2093 | author name string | I Izquierdo | |
R R Brentani | |||
F Dal-Pizzol | |||
M E Andrades | |||
F Klamt | |||
J C Fonseca Moreira | |||
E G da Silva | |||
M L Conte da Frota | |||
P2860 | cites work | Normal inhibitory avoidance learning and anxiety, but increased locomotor activity in mice devoid of PrP(C) | Q28145925 |
Copper stimulates endocytosis of the prion protein | Q28589040 | ||
Catalase in vitro | Q29615710 | ||
Mammalian prion proteins. | Q30326201 | ||
Degradation of oxidized proteins in mammalian cells. | Q30427697 | ||
Lipid peroxidation in hippocampus early and late after status epilepticus induced by pilocarpine or kainic acid in Wistar rats. | Q31440143 | ||
Molecular biology of prion propagation. | Q33665932 | ||
Oxidative stress and gene regulation | Q33853144 | ||
Metals and neuroscience. | Q33878376 | ||
Prion disease: A loss of antioxidant function? | Q34018111 | ||
A new variant of Creutzfeldt-Jakob disease in the UK. | Q34374893 | ||
Localization of the mRNA for a chicken prion protein by in situ hybridization | Q36291248 | ||
Polyamines: from molecular biology to clinical applications | Q37421694 | ||
Protein oxidation and degradation during proliferative senescence of human MRC-5 fibroblasts | Q40888525 | ||
Proteolysis in cultured liver epithelial cells during oxidative stress. Role of the multicatalytic proteinase complex, proteasome. | Q41370949 | ||
Bovine spongiform encephalopathy and early onset variant Creutzfeldt-Jakob disease | Q41652295 | ||
Identification of the Cu2+ binding sites in the N-terminal domain of the prion protein by EPR and CD spectroscopy | Q41983149 | ||
Ornithine decarboxylase activity in vitro in response to acute hypoxia: a novel use of newborn rat brain slices | Q42513260 | ||
Prion protein expression and superoxide dismutase activity | Q42991570 | ||
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein | Q43522858 | ||
Prion protein selectively binds copper(II) ions | Q46492410 | ||
A new mechanism broadening the role of prion proteins in neurodegeneration. | Q48013082 | ||
Free radical-induced elevation of ornithine decarboxylase activity in developing rat brain slices | Q48655749 | ||
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity | Q48670908 | ||
Loss of cerebellar Purkinje cells in aged mice homozygous for a disrupted PrP gene | Q49010616 | ||
Altered circadian activity rhythms and sleep in mice devoid of prion protein | Q59071240 | ||
Increased Sensitivity to Seizures in Mice Lacking Cellular Prion Protein | Q59683939 | ||
Determination of carbonyl content in oxidatively modified proteins | Q68161213 | ||
Determination of the production of superoxide radicals and hydrogen peroxide in mitochondria | Q70214743 | ||
Hypothesis: spermine may be an important epidermal antioxidant | Q70793572 | ||
Impairment of DNA replication within one cell cycle after seeding of cells in the presence of a polyamine-biosynthesis inhibitor | Q71118021 | ||
Redox-regulation of intrinsic prion expression in multicellular prostate tumor spheroids | Q73370517 | ||
Brain copper content and cuproenzyme activity do not vary with prion protein expression level | Q73538276 | ||
DNA damage, repair, and antioxidant systems in brain regions: a correlative study | Q73644418 | ||
Retinol-induced elevation of ornithine decarboxylase activity in cultured rat Sertoli cells is attenuated by free radical scavenger and by iron chelator | Q74159676 | ||
P433 | issue | 10 | |
P921 | main subject | prion protein family | Q24724413 |
P304 | page(s) | 1137-1144 | |
P577 | publication date | 2001-05-01 | |
P1433 | published in | Free Radical Biology and Medicine | Q5500023 |
P1476 | title | Imbalance of antioxidant defense in mice lacking cellular prion protein | |
P478 | volume | 30 |
Q30354332 | A mechanism for copper inhibition of infectious prion conversion |
Q43747316 | Affinity, speciation, and molecular features of copper(II) complexes with a prion tetraoctarepeat domain in aqueous solution: insights into old and new results |
Q41217812 | Age-dependent neuromuscular impairment in prion protein knockout mice. |
Q36573251 | Bovine spongiform encephalopathy in Japan: history and recent studies on oxidative stress in prion diseases |
Q37605018 | Brain iron homeostasis: from molecular mechanisms to clinical significance and therapeutic opportunities |
Q55002430 | Calbindin-D28k in the Brain Influences the Expression of Cellular Prion Protein. |
Q30429098 | Calcium overload and in vitro apoptosis of the C6 glioma cells mediated by sonodynamic therapy (hematoporphyrin monomethyl ether and ultrasound) |
Q36006619 | Cellular prion protein neuroprotective function: implications in prion diseases |
Q42174876 | Cellular prion protein promotes regeneration of adult muscle tissue. |
Q35018699 | Cellular prion protein: implications in seizures and epilepsy |
Q34536249 | Cellular prion protein: on the road for functions |
Q48498685 | Changes in antioxidant defense enzymes after d-amphetamine exposure: implications as an animal model of mania |
Q48597039 | Cognitive performance of patients with mesial temporal lobe epilepsy is not associated with human prion protein gene variant allele at codons 129 and 171. |
Q36640347 | Copper and the prion protein: methods, structures, function, and disease |
Q35668960 | Copper binding in the prion protein |
Q42731558 | Copper coordination in the full-length, recombinant prion protein |
Q52927715 | Copper is required for prion protein-associated superoxide dismutase-I activity in Pichia pastoris. |
Q43938462 | Cortical spreading depression and gene regulation: relevance to migraine |
Q37621341 | CpG site DNA methylation patterns reveal a novel regulatory element in the mouse prion protein gene |
Q40077734 | Critical roles of reactive oxygen species in mitochondrial permeability transition in mediating evodiamine-induced human melanoma A375-S2 cell apoptosis |
Q46777937 | Cross-talk between the octarepeat domain and the fifth binding site of prion protein driven by the interaction of copper(II) with the N-terminus |
Q36981826 | Cytosolic caspases mediate mislocalised SOD2 depletion in an in vitro model of chronic prion infection. |
Q34081999 | Deficiency of prion protein induces impaired autophagic flux in neurons |
Q48278342 | Differentiating prion strains using dendrimers |
Q37258238 | Discriminant analysis of prion sequences for prediction of susceptibility |
Q34608384 | Effects of maintenance electroshock on the oxidative damage parameters in the rat brain. |
Q28592762 | Expression of prion protein increases cellular copper binding and antioxidant enzyme activities but not copper delivery |
Q48119181 | Expression of the prion protein gene (PRNP) and cellular prion protein (PrPc) in cattle and sheep fetuses and maternal tissues during pregnancy. |
Q37261825 | Functional implications of multistage copper binding to the prion protein. |
Q40070117 | Hemin interactions and alterations of the subcellular localization of prion protein |
Q39574917 | Hybrid lipoic acid derivatives to attack prion disease on multiple fronts |
Q34964641 | IGF-1-induced enhancement of PRNP expression depends on the negative regulation of transcription factor FOXO3a |
Q37314442 | Identification of the copper(II) coordinating residues in the prion protein by metal-catalyzed oxidation mass spectrometry: evidence for multiple isomers at low copper(II) loadings |
Q34221769 | Impairment of superoxide dismutase activation by N-terminally truncated prion protein (PrP) in PrP-deficient neuronal cell line |
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Q48498718 | Long lasting effects of electroconvulsive seizures on brain oxidative parameters |
Q38940886 | MEK1 transduces the prion protein N2 fragment antioxidant effects |
Q37957126 | Metal attenuating therapies in neurodegenerative disease |
Q36217394 | Methionine oxidation perturbs the structural core of the prion protein and suggests a generic misfolding pathway |
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Q44352413 | Modulation of oxidative stress in response to gamma-radiation in human glioma cell lines |
Q24292484 | Molecular features of the copper binding sites in the octarepeat domain of the prion protein |
Q38234645 | Multitarget ligands and theranostics: sharpening the medicinal chemistry sword against prion diseases. |
Q48196991 | Mutagenesis studies in transgenic Xenopus intermediate pituitary cells reveal structural elements necessary for correct prion protein biosynthesis |
Q36961166 | New molecular insights into cellular survival and stress responses: neuroprotective role of cellular prion protein (PrPC). |
Q48185616 | No superoxide dismutase activity of cellular prion protein in vivo |
Q36123408 | Normal cellular prion protein protects against manganese-induced oxidative stress and apoptotic cell death |
Q36676179 | Novel aspects of prions, their receptor molecules, and innovative approaches for TSE therapy |
Q43794690 | Oxidative impairment in scrapie-infected mice is associated with brain metals perturbations and altered antioxidant activities |
Q73470375 | Oxidative parameters and mortality in sepsis induced by cecal ligation and perforation |
Q84514300 | Plasma levels of oxidative stress biomarkers and long-term cognitive performance after severe head injury |
Q44458239 | Plasma oxidative parameters and mortality in patients with severe burn injury |
Q28206331 | PrP knock-out and PrP transgenic mice in prion research |
Q35795086 | Prion Protein Does Not Confer Resistance to Hippocampus-Derived Zpl Cells against the Toxic Effects of Cu2+, Mn2+, Zn2+ and Co2+ Not Supporting a General Protective Role for PrP in Transition Metal Induced Toxicity |
Q47606278 | Prion Protein Family Contributes to Tumorigenesis via Multiple Pathways |
Q38841674 | Prion protein "gamma-cleavage": characterizing a novel endoproteolytic processing event. |
Q35102832 | Prion protein accumulation and neuroprotection in hypoxic brain damage |
Q62066608 | Prion protein cleavage fragments regulate adult neural stem cell quiescence through redox modulation of mitochondrial fission and SOD2 expression |
Q35222198 | Prion protein expression and functional importance in skeletal muscle |
Q44597269 | Prion protein expression modulates neuronal copper content |
Q33869473 | Prion protein expression regulates embryonic stem cell pluripotency and differentiation |
Q30924592 | Prion protein self-peptides modulate prion interactions and conversion |
Q48959053 | Prnp gene and cerebellum volume in patients with refractory mesial temporal lobe epilepsy |
Q33566142 | Reactive oxygen species contribute to oridonin-induced apoptosis and autophagy in human cervical carcinoma HeLa cells |
Q33830151 | Redox control of prion and disease pathogenesis |
Q38215344 | Review of studies that have used knockout mice to assess normal function of prion protein under immunological or pathophysiological stress. |
Q47681355 | Role of hypoxia‑mediated cellular prion protein functional change in stem cells and potential application in angiogenesis (Review). |
Q39391056 | Role of the cellular prion protein in the neuron adaptation strategy to copper deficiency |
Q31050819 | Spectroscopic and Theoretical Study of Cu(I) Binding to His111 in the Human Prion Protein Fragment 106-115. |
Q49439201 | Stress Resilience of Spermatozoa and Blood Mononuclear Cells without Prion Protein |
Q60213094 | Structure-Related Oxidative Damage in Rat Brain After Acute and Chronic Electroshock |
Q47393014 | Surgical outcome in mesial temporal sclerosis correlates with prion protein gene variant |
Q90047524 | The Quest for Cellular Prion Protein Functions in the Aged and Neurodegenerating Brain |
Q42731475 | The affinity of copper binding to the prion protein octarepeat domain: evidence for negative cooperativity |
Q33623592 | The biological function of the cellular prion protein: an update |
Q34784392 | The biology of the cellular prion protein |
Q36003019 | The cellular prion protein (PrP(C)): its physiological function and role in disease |
Q42703327 | The octarepeat domain of the prion protein binds Cu(II) with three distinct coordination modes at pH 7.4. |
Q37080450 | The prion protein knockout mouse: a phenotype under challenge |
Q53361326 | The role of copper ions in pathophysiology and fluorescent sensors for the detection thereof. |
Q42080796 | The role of the octarepeat region in neuroprotective function of the cellular prion protein |
Q30386079 | The sour side of neurodegenerative disorders: the effects of protein glycation. |
Q30593594 | Utilizing NMR and EPR spectroscopy to probe the role of copper in prion diseases. |
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