Cloning of a gene cluster encoding enzymes responsible for the mevalonate pathway from a terpenoid-antibiotic-producing Streptomyces strain (scientific article published in July 2001)

Identification of a thiamin-dependent synthase in Escherichia coli required for the formation of the 1-deoxy-D-xylulose 5-phosphate precursor to isoprenoids, thiamin, and pyridoxol

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Improved tools for biological sequence comparison

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Biosynthesis of terpenoids: YchB protein of Escherichia coli phosphorylates the 2-hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol

Q24673194

A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis

Q24675379

Cytidine 5'-triphosphate-dependent biosynthesis of isoprenoids: YgbP protein of Escherichia coli catalyzes the formation of 4-diphosphocytidyl-2-C-methylerythritol

Q24675400

Biosynthesis of terpenoids: YgbB protein converts 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate to 2C-methyl-D-erythritol 2,4-cyclodiphosphate

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Basic local alignment search tool

Q25938991

Isolation and characterization of yeast mutants blocked in mevalonic acid formation

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The relationship between base composition and codon usage in bacterial genes and its use for the simple and reliable identification of protein-coding sequences

Q34245641

Cloning and nucleotide sequence of the gene responsible for chlorination of tetracycline

Q34300098

Cloning and characterization of a gene from Escherichia coli encoding a transketolase-like enzyme that catalyzes the synthesis of D-1-deoxyxylulose 5-phosphate, a common precursor for isoprenoid, thiamin, and pyridoxol biosynthesis.

Q35903312

Cloning of genes governing the deoxysugar portion of the erythromycin biosynthesis pathway in Saccharopolyspora erythraea (Streptomyces erythreus)

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A gene cluster for the mevalonate pathway from Streptomyces sp. Strain CL190.

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Isoprenoid biosynthesis in bacteria: a novel pathway for the early steps leading to isopentenyl diphosphate

Q42815553

Gene cloning and overexpression of a geranylgeranyl diphosphate synthase of an extremely thermophilic bacterium, Thermus thermophilus

Q43026357

Mevalonate kinase in lysates of cultured human fibroblasts and lymphoblasts: kinetic properties, assay conditions, carrier detection and measurement of residual activity in a patient with mevalonic aciduria.

Q46573608

Cloning of the gene encoding 3-hydroxy-3-methylglutaryl coenzyme A reductase from terpenoid antibiotic-producing Streptomyces strains

Q47887189

Cloning and analysis of the promoter region of the erythromycin resistance gene (ermE) of Streptomyces erythraeus

Q48383564

The mRNA for the 23S rRNA methylase encoded by the ermE gene of Saccharopolyspora erythraea is translated in the absence of a conventional ribosome-binding site.

Q54192770

Construction and characterization of Escherichia coli disruptants defective in the yaeM gene.

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Promoter constructions for efficient secretion expression in Streptomyces lividans.

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Isolation and structural elucidation of an antioxidative agent, naphterpin

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Biosynthetic studies of terpentecin

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Isolation and characterization of terpentecin, a new antitumor antibiotic

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Enzymatic hydrolysis of polyprenyl pyrophosphates

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Mevalonate kinase

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Isoprenoid biosynthesis in bacteria: two different pathways?

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Organization and nature of fortimicin A (astromicin) biosynthetic genes studied using a cosmid library of Micromonospora olivasterospora DNA

Q104936400

P433

issue

P921

main subject

antibiotic

Q12187

terpenoids

Q426694

Streptomyces

Q1144013

Kitasatospora griseola

Q25860966

terpentecin

Q27122026

2-[(2S)-2-[(1R)-2-[(1S,2S,3R,4aS)-3-hydroxy-1,2,4a,5-tetramethyl-4-oxo-3,7,8,8a-tetrahydro-2H-naphthalen-1-yl]-1-hydroxyethyl]oxiran-2-yl]-2-oxoacetaldehyde

Q105119808

P6954

online access status

open access

Q232932

P304

page(s)

1627-1635

P577

publication date

2001-07-01

P1433

published in

Bioscience, Biotechnology, and Biochemistry

Q11192374

P1476

title

Cloning of a gene cluster encoding enzymes responsible for the mevalonate pathway from a terpenoid-antibiotic-producing Streptomyces strain

P478

volume

Reverse relations

cites work (P2860)

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Q38288794	Growth-phase dependent expression of the mevalonate pathway in a terpenoid antibiotic-producing Streptomyces strain
Q44449774	Interconversion of the product specificity of type I eubacterial farnesyl diphosphate synthase and geranylgeranyl diphosphate synthase through one amino acid substitution
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P356	DOI	10.1271/BBB.65.1627
P953	full work available at URL	https://academic.oup.com/bbb/article-pdf/65/7/1627/35019926/bbb1627.pdf
P698	PubMed publication ID	11515548