Equine herpesvirus 1 glycoprotein D expressed in Pichia pastoris is hyperglycosylated and elicits a protective immune response in the mouse model of EHV-1 disease

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Equine herpesvirus 1 glycoprotein D expressed in Pichia pastoris is hyperglycosylated and elicits a protective immune response in the mouse model of EHV-1 disease is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0168-1702(01)00337-9
P698PubMed publication ID11551653

P2093author name stringGilkerson JR
Love DN
Whalley JM
Wellington JE
Ruitenberg KM
P2860cites workThe intracellular production and secretion of HIV-1 envelope protein in the methylotrophic yeast Pichia pastorisQ72738167
Analysis of the Genome of Equine Herpesvirus Type 1: Arrangement of Cleavage Sites for Restriction Endonucleases EcoRI, BglII and BamHIQ72918350
Functional phytohemagglutinin (PHA) and Galanthus nivalis agglutinin (GNA) expressed in Pichia pastoris correct N-terminal processing and secretion of heterologous proteins expressed using the PHA-E signal peptideQ73003722
Potential of DNA-mediated vaccination for equine herpesvirus 1Q73028836
A prime-boost immunization strategy with DNA and recombinant baculovirus-expressed protein enhances protective immunogenicity of glycoprotein D of equine herpesvirus 1 in naïve and infection-primed miceQ73318524
Expression and purification of His-tagged beta-1,4-galactosyltransferase in yeast and in COS cellsQ73941053
Equine herpesvirus 1 (EHV-1) glycoprotein D DNA inoculation in horses with pre-existing EHV-1/EHV-4 antibodyQ74182723
Immunization of BALB/c mice with DNA encoding equine herpesvirus 1 (EHV-1) glycoprotein D affords partial protection in a model of EHV-1-induced abortionQ74269517
Variation in N-linked oligosaccharide structures on heterologous proteins secreted by the methylotrophic yeast Pichia pastorisQ77471895
Primary and challenge infection of mice with equine herpesvirus 1, strain HSV25AQ77741414
Use of Pichia pastoris for expression of recombinant proteinsQ78083807
DNA-mediated immunization with glycoprotein D of equine herpesvirus 1 (EHV-1) in a murine model of EHV-1 respiratory infectionQ78164037
Mutations within the proteolytic cleavage site of the Rous sarcoma virus glycoprotein that block processing to gp85 and gp37Q30403429
Heterologous protein expression in the methylotrophic yeast Pichia pastorisQ33820603
Strategies for optimal synthesis and secretion of heterologous proteins in the methylotrophic yeast Pichia pastorisQ36865705
Expression of equine herpesvirus 1 glycoprotein D by using a recombinant baculovirusQ40048086
Recent advances in the expression of foreign genes in Pichia pastorisQ40533559
Equine herpesviruses 4 (equine rhinopneumonitis virus) and 1 (equine abortion virus).Q40551622
The trigeminal ganglion is a location for equine herpesvirus 1 latency and reactivation in the horseQ40697575
Yeast-secreted bovine herpesvirus type 1 glycoprotein D has authentic conformational structure and immunogenicityQ41117744
Expression and characterization of equine herpesvirus 1 glycoprotein D in mammalian cell linesQ41245831
N-terminal sequence analysis of equine herpesvirus 1 glycoproteins D and B and evidence for internal cleavage of the gene 71 productQ41255203
Characterization of immune responses to baculovirus-expressed equine herpesvirus type 1 glycoproteins D and H in a murine modelQ41456995
Sequence analysis of a glycoprotein D gene homolog within the unique short segment of the EHV-1 genomeQ41704332
The pathogenesis of equine herpesvirus type 1 in the mouse: a new model for studying host responses to the infectionQ41735689
Endoproteolytic cleavage of gp160 is required for the activation of human immunodeficiency virusQ41876028
Identification and comparative sequence analysis of a gene in equine herpesvirus 1 with homology to the herpes simplex virus glycoprotein D geneQ42614342
Equine herpesvirus type 1 unique short fragment encodes glycoproteins with homology to herpes simplex virus type 1 gD, gI and gE.Q42632643
DNA priming-protein boosting enhances both antigen-specific antibody and Th1-type cellular immune responses in a murine herpes simplex virus-2 gD vaccine modelQ44394460
Protective immunity against equine herpesvirus type-1 (EHV-1) infection in mice induced by recombinant EHV-1 gD.Q44768117
Protection of mice against a lethal influenza virus challenge after immunization with yeast-derived secreted influenza virus hemagglutininQ45750536
High level expression of equine herpesvirus 1 glycoproteins D and H and their role in protection against virus challenge in the C3H (H-2Kk) murine modelQ45760758
Immune responses and protective efficacy of recombinant baculovirus-expressed glycoproteins of equine herpesvirus 1 (EHV-1) gB, gC and gD alone or in combinations in BALB/c miceQ47911816
The secretion of human serum albumin from the yeast Saccharomyces cerevisiae using five different leader sequencesQ48933387
Protection of mice against a lethal influenza challenge by immunization with yeast-derived recombinant influenza neuraminidaseQ49093623
Studies on equine herpesviruses. 3. The incidence in Queensland of three different equine herpesvirus infections.Q53735579
A chimeric protein comprised of bovine herpesvirus type 1 glycoprotein D and bovine interleukin-6 is secreted by yeast and possesses biological activities of both molecules.Q54197671
Oligosaccharides of recombinant mouse gelatinase B variantsQ57584697
Characterization of the glycoprotein D gene products of equine herpesvirus 1 using a prokaryotic cell expression vectorQ67488440
Intracellular production of a major cytomegalovirus antigenic protein in the methylotrophic yeast Pichia pastorisQ71778134
Equine herpesvirus 1 HVS25A isolated from an aborted foetus produces disease in balb/C miceQ72307612
P433issue1-2
P921main subjectPichia pastorisQ148697
P304page(s)125-135
P577publication date2001-11-01
P1433published inVirus ResearchQ15749215
P1476titleEquine herpesvirus 1 glycoprotein D expressed in Pichia pastoris is hyperglycosylated and elicits a protective immune response in the mouse model of EHV-1 disease
P478volume79

Reverse relations

cites work (P2860)
Q40588197A protective effect of epidermal powder immunization in a mouse model of equine herpesvirus-1 infection
Q34738751Enhancement of immune responses by an attenuated Salmonella enterica serovar Typhimurium strain secreting an Escherichia coli heat-labile enterotoxin B subunit protein as an adjuvant for a live Salmonella vaccine candidate
Q43531044Equine herpesvirus 1 glycoprotein D expressed in E. coli provides partial protection against equine herpesvirus infection in mice and elicits virus-neutralizing antibodies in the horse
Q35199961Expression and analysis of the glycosylation properties of recombinant human erythropoietin expressed in Pichia pastoris
Q43239997Expression and structural characterization of peripherin/RDS, a membrane protein implicated in photoreceptor outer segment morphology.
Q44631879Inoculation of mares and very young foals with EHV-1 glycoproteins D and B reduces virus shedding following respiratory challenge with EHV-1.
Q38839398Intramuscular Immunization of Mice with the Live-Attenuated Herpes Simplex Virus 1 Vaccine Strain VC2 Expressing Equine Herpesvirus 1 (EHV-1) Glycoprotein D Generates Anti-EHV-1 Immune Responses in Mice
Q33266956Recombinant single chain Fv antibodies specific for glycoprotein D of equid herpesvirus 1.
Q81589496Serum antibody responses to equine herpesvirus 1 glycoprotein D in horses, pregnant mares and young foals
Q36845824Trial watch: DNA vaccines for cancer therapy
Q54484571Vaccine and adjuvant activity of recombinant subunit B of E. coli enterotoxin produced in yeast.

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