Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise

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Supplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise is …
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scholarly articleQ13442814

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P356DOI10.1016/S0891-5849(01)00640-2
P698PubMed publication ID11557312
P5875ResearchGate publication ID11791143

P2093author name stringJacobs C
Halliwell B
Childs A
Kaminski T
Leeuwenburgh C
P2860cites workA rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Noncyclooxygenase oxidative formation of a series of novel prostaglandins: analytical ramifications for measurement of eicosanoidsQ28280810
Role of free radicals and catalytic metal ions in human disease: an overviewQ29618022
Toward a new recommended dietary allowance for vitamin C based on antioxidant and health effects in humansQ33652108
Antioxidant defenses and lipid peroxidation in human blood plasmaQ33688237
Exercise training-induced alterations in skeletal muscle antioxidant capacity: a brief reviewQ33693424
The role of natural antioxidants in preserving the biological activity of endothelium-derived nitric oxideQ34006323
The effects of iron and vitamin C co-supplementation on oxidative damage to DNA in healthy volunteersQ34066606
Dietary carcinogens and anticarcinogens. Oxygen radicals and degenerative diseasesQ34256779
Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agentQ34501431
Iron supplementation generates hydroxyl radical in vivo. An ESR spin-trapping investigationQ35763671
Oxygen radicals and human diseaseQ39668375
Oxidative and lysosomal capacity in skeletal muscle of mice after endurance training of different intensitiesQ40175199
Exhaustive physical exercise and acid hydrolase activity in mouse skeletal muscle. A histochemical studyQ40183963
Iron mobilization from ferritin by superoxide derived from stimulated polymorphonuclear leukocytes. Possible mechanism in inflammation diseasesQ40984655
Iron-induced ascorbate oxidation in plasma as monitored by ascorbate free radical formation. No spin-trapping evidence for the hydroxyl radical in iron-overloaded plasmaQ41828536
Hydroxyl radical production in body fluids Roles of metal ions, ascorbate and superoxideQ41986897
Effects of oxyradicals on oxymyoglobin. Deoxygenation, haem removal and iron releaseQ41994343
Blood levels of reduced/oxidized glutathione and plasma concentration of ascorbic acid during eccentric and concentric exercises of similar energy costQ42476112
N-acetyl-L-cysteine protects SHSY5Y neuroblastoma cells from oxidative stress and cell cytotoxicity: effects on beta-amyloid secretion and tau phosphorylationQ43516547
Superoxide ion as a primary reductant in ascorbate-mediated ferritin iron releaseQ44539910
Failure of N-acetylcysteine to reduce low-density lipoprotein oxidizability in healthy subjectsQ45027328
Ascorbyl radical as natural indicator of oxidative stress: quantitative regularities.Q50770467
Ascorbyl radical formation in patients with sepsis: effect of ascorbate loading.Q51581411
N-Acetylcysteine delays age-associated memory impairment in mice: role in synaptic mitochondria.Q52029587
N-acetyl-cysteine: protective agent or promoter of gastric damage?Q54292490
Vitamin C exhibits pro-oxidant properties.Q55067476
8-Hydroxydeoxyguanosine in vitro: Effects of glutathione, ascorbate, and 5-aminosalicylic acidQ61794871
On the limited ability of superoxide to release iron from ferritinQ68487728
Scavenging of hypochlorous acid and of myoglobin-derived oxidants by the cardioprotective agent mercaptopropionylglycineQ68489479
Iron promoters of the Fenton reaction and lipid peroxidation can be released from haemoglobin by peroxidesQ68963110
Mechanism of N-acetylcysteine (NAC) and other thiols as both positive and negative modifiers of MNNG-induced mutagenicity in V79 Chinese hamster cellsQ69395725
Delayed-onset muscle damage and lipid peroxidation in man after a downhill runQ69706322
Oxidative damage to human red cells induced by copper and iron complexes in the presence of ascorbateQ69774690
Assays of glutathione peroxidaseQ71365824
Measurement of iron and copper in biological systems: bleomycin and copper-phenanthroline assaysQ71630063
Heart, liver, and skeletal muscle myeloperoxidase activity during exerciseQ71794195
Reevaluation of assay methods and establishment of kit for superoxide dismutase activityQ72412554
N-acetyl L-cysteine attenuates oxidant-mediated toxicity induced by chrysotile fibersQ73081884
Different effects of strenuous eccentric exercise on the accumulation of neutrophils in muscle in women and menQ73158235
Antioxidant activity of vitamin C in iron-overloaded human plasmaQ73427470
In-vivo glutathione elevation protects against hydroxyl free radical-induced protein oxidation in rat brainQ73453586
Effects of prior exercise on eccentric exercise-induced neutrophilia and enzyme releaseQ73491654
Interaction between 6-hydroxydopamine and transferrin: "Let my iron go"Q73570969
The cytokine response to strenuous exerciseQ77634722
Effects of N-acetylcysteine and 2,3-dimercaptosuccinic acid on lead induced oxidative stress in rat lensesQ77725665
Hydroxyl radical generation during exercise increases mitochondrial protein oxidation and levels of urinary dityrosineQ78115668
P433issue6
P921main subjectvitaminQ34956
vitamin CQ199678
P304page(s)745-753
P577publication date2001-09-01
P1433published inFree Radical Biology and MedicineQ5500023
P1476titleSupplementation with vitamin C and N-acetyl-cysteine increases oxidative stress in humans after an acute muscle injury induced by eccentric exercise
P478volume31

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cites work (P2860)
Q37097482Acute exercise and oxidative stress: a 30 year history
Q34639013Aerobic and combined exercise sessions reduce glucose variability in type 2 diabetes: crossover randomized trial
Q35806212Anaerobic exercise and oxidative stress: a review
Q37716098Antioxidant and anti-nociceptive effects of Phyllanthus amarus on improving exercise recovery in sedentary men: a randomized crossover (double-blind) design
Q37953509Antioxidant supplementation during exercise training: beneficial or detrimental?
Q90005528Antioxidant supplements and endurance exercise: Current evidence and mechanistic insights
Q35795854Antioxidant-induced stress
Q47313144Antioxidants for preventing and reducing muscle soreness after exercise.
Q64251272C-Reactive Protein Is Elevated Only in High Creatine Kinase Responders to Muscle Damaging Exercise
Q35223608Chronic alcohol ingestion delays skeletal muscle regeneration following injury
Q92130734Curcumin supplementation attenuates the decrease in endothelial function following eccentric exercise
Q37062649Deleterious consequences of antioxidant supplementation on lifespan in a wild-derived mammal
Q38158175Dietary strategies to recover from exercise-induced muscle damage
Q33612951Dietary thiols in exercise: oxidative stress defence, exercise performance, and adaptation
Q37182377Differential effect of ascorbic acid and n-acetyl-L-cysteine on arsenic trioxide-mediated oxidative stress in human leukemia (HL-60) cells
Q28389360Do antioxidant supplements interfere with skeletal muscle adaptation to exercise training?
Q37630513Does antioxidant vitamin supplementation protect against muscle damage?
Q37349959Does physical exercise modify antioxidant requirements?
Q50955796Eccentric exercise transiently affects mice skeletal muscle mitochondrial function.
Q91945028Effect of Vitamins C and E Co-Supplementation on Serum C-Reactive Protein Level: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
Q45083854Effect of a high-altitude expedition to a Himalayan peak (Pumori, 7,161 m) on plasma and erythrocyte antioxidant profile
Q46044971Effect of antioxidant supplementation on leucocyte expression of reactive oxygen species in athletes.
Q46684508Effect of astaxanthin supplementation on paraoxonase 1 activities and oxidative stress status in young soccer players
Q42839114Effect of eccentric training on mitochondrial function and oxidative stress in the skeletal muscle of rats.
Q37323782Effect of exercise on oxidative stress biomarkers.
Q46812990Effect of resistance exercise and carbohydrate ingestion on oxidative stress
Q44466790Effect of vitamin E and eccentric exercise on selected biomarkers of oxidative stress in young and elderly men.
Q33710883Effect of α -Lipoic Acid on Oxidative Stress in End-Stage Renal Disease Patients Receiving Intravenous Iron
Q59049261Effects of Differing Dosages of Pomegranate Juice Supplementation after Eccentric Exercise
Q40101507Effects of Pomegranate Juice Supplementation on Oxidative Stress Biomarkers Following Weightlifting Exercise
Q84680220Effects of a Fruit/Berry/Vegetable Supplement on Muscle Function and Oxidative Stress
Q64098994Effects of cold water immersion and compression garment use after eccentric exercise on recovery
Q45017285Effects of dietary supplementation with vitamins C and E on muscle function during and after eccentric contractions in humans
Q58502195Effects of mate tea consumption on muscle strength and oxidative stress markers after eccentric exercise
Q36286956Effects of powdered Montmorency tart cherry supplementation on an acute bout of intense lower body strength exercise in resistance trained males.
Q43975870Effects of taurine supplementation following eccentric exercise in young adults
Q42076842Enhancing effects of intracellular ascorbic acid on peroxynitrite-induced U937 cell death are mediated by mitochondrial events resulting in enhanced sensitivity to peroxynitrite-dependent inhibition of complex III and formation of hydrogen peroxide
Q57160430Exercise-Induced Oxidative Stress and the Effects of Antioxidant Intake from a Physiological Viewpoint
Q45979012Exercise-induced elevation in plasma oxidative generating capability augments the temporal inflammatory response stimulated by lipopolysaccharide.
Q36334777Exercise-induced oxidative stress:myths, realities and physiological relevance
Q48949741Exercise-induced oxidative-nitrosative stress is associated with impaired dynamic cerebral autoregulation and blood-brain barrier leakage
Q36965005Fostering antioxidant defences: up-regulation of antioxidant genes or antioxidant supplementation?
Q30320174Further investigations on the role of ascorbic acid in stratum corneum lipid models after UV exposure
Q40470158Gly482Ser PGC-1α Gene Polymorphism and Exercise-Related Oxidative Stress in Amyotrophic Lateral Sclerosis Patients.
Q34551918Hydrogen improves glycemic control in type1 diabetic animal model by promoting glucose uptake into skeletal muscle
Q44803711Hydrogen peroxide induced apoptosis in amnion-derived WISH cells is not inhibited by vitamin C.
Q46346231Hypochlorous acid is a potent inactivator of human plasminogen at concentrations secreted by activated granulocytes
Q50499983Impact of different resistance training protocols on muscular oxidative stress parameters.
Q94370402Influence of antioxidant therapy on the clinical status of multiple trauma patients. A retrospective single center study
Q28066359Insights into the molecular etiology of exercise-induced inflammation: opportunities for optimizing performance
Q41573516Intramitochondrial Ascorbic Acid Enhances the Formation of Mitochondrial Superoxide Induced by Peroxynitrite via a Ca2+-Independent Mechanism
Q37624905Iron Supplementation Effects on Redox Status following Aseptic Skeletal Muscle Trauma in Adults and Children
Q33358057Iron accumulation with age, oxidative stress and functional decline
Q40744250Iron status markers are only transiently affected by a football game.
Q24795785Iron supplements: the quick fix with long-term consequences
Q34960365Isoprostanes as a biomarker of lipid peroxidation in humans: physiology, pharmacology and clinical implications
Q33745047Mechanism of N-acetyl-cysteine inhibition on the cytotoxicity induced by titanium dioxide nanoparticles in JB6 cells transfected with activator protein-1.
Q39084320Mitochondrial ascorbic acid is responsible for enhanced susceptibility of U937 cells to the toxic effects of peroxynitrite
Q43114183Modulatory effect of N-acetylcysteine on pro-antioxidant status and haematological response in healthy men.
Q34202351Modulatory effects of low-dose hydrogen peroxide on the function of human plasmacytoid dendritic cells
Q37617755Montmorency cherries reduce the oxidative stress and inflammatory responses to repeated days high-intensity stochastic cycling.
Q39674393N-Acetylcysteine interacts with copper to generate hydrogen peroxide and selectively induce cancer cell death
Q35388320N-acetylcysteine is effective for prevention but not for treatment of folic acid-induced acute kidney injury in mice
Q36678635NRF2 and the Phase II Response in Acute Stress Resistance Induced by Dietary Restriction
Q52564739Nano-selenium and its nanomedicine applications: a critical review.
Q80267240Nitric oxide inhibition decreases bleomycin-detectable iron in spleen, bone marrow cells and heart but not in liver in exercise rats
Q55094387Nutrition and Supplementation in Soccer.
Q36435659Oxidative stress : relationship with exercise and training
Q35160363Oxidative stress, exercise, and antioxidant supplementation
Q46681871Oxygen radical absorbance capacity (ORAC) and exercise-induced oxidative stress in trotters
Q39094813Performance and Side Effects of Supplementation with N-Acetylcysteine: A Systematic Review and Meta-Analysis
Q45969313Potentially detrimental effects of N-acetylcysteine on renal function in knee arthroplasty.
Q47830220Pre-clinical evaluation of N-acetylcysteine reveals side effects in the mdx mouse model of Duchenne muscular dystrophy.
Q36253656Prior exercise and antioxidant supplementation: effect on oxidative stress and muscle injury
Q38830382Prospective study of serum cysteine and cysteinylglycine and cancer of the head and neck, esophagus, and stomach in a cohort of male smokers
Q50787620Relationship of vitamin E metabolism and oxidation in exercising human subjects.
Q44533829Role of ascorbic acid in the modulation of inhibition of platelet aggregation by polymorphonuclear leukocytes
Q35012446Role of the antioxidant ascorbate in hibernation and warming from hibernation
Q96113189Safety issues and harmful pharmacological interactions of nutritional supplements in Duchenne muscular dystrophy: considerations for Standard of Care and emerging virus outbreaks
Q36215390Salivary antioxidants of male athletes after aerobic exercise and garlic supplementation on: A randomized, double blind, placebo-controlled study
Q39858645Short-term blackcurrant extract consumption modulates exercise-induced oxidative stress and lipopolysaccharide-stimulated inflammatory responses
Q46484943Supplemental ascorbate and exercise-induced IL-6 metabolism: focus on Fenton chemistry and redox-regulation of vascular homeostasis
Q37343095Symptomatic and functional responses to concentric-eccentric isokinetic versus eccentric-only isotonic exercise
Q53272671Taurine supplementation decreases oxidative stress in skeletal muscle after eccentric exercise.
Q46283042The Effect of Taurine on the Recovery from Eccentric Exercise-Induced Muscle Damage in Males
Q36090565The Pigment in Alkaptonuria Relationship to Melanin and Other Coloured Substances: A Review of Metabolism, Composition and Chemical Analysis
Q34244539The affect on delayed onset muscle soreness recovery for ultrasound with bee venom
Q42789059The antioxidant role of glutathione and N-acetyl-cysteine supplements and exercise-induced oxidative stress
Q39226803The effect of an acute antioxidant supplementation compared with placebo on performance and hormonal response during a high volume resistance training session
Q36980443The effect of methyl sulphonyl methane supplementation on biomarkers of oxidative stress in sport horses following jumping exercise
Q37192506The effect of muscle-damaging exercise on blood and skeletal muscle oxidative stress: magnitude and time-course considerations
Q34094019The impact of vitamin C supplementation in pregnancy and in vitro upon fetal membrane strength and remodeling
Q37167554The prevention and treatment of exercise-induced muscle damage.
Q38233230The role of N-acetylcysteine in the management of acute and chronic pulmonary complications of sulfur mustard: a literature review
Q36822348The role of nutritional supplements in the prevention and treatment of resistance exercise-induced skeletal muscle injury
Q38268275The role of oxidative, inflammatory and neuroendocrinological systems during exercise stress in athletes: implications of antioxidant supplementation on physiological adaptation during intensified physical training.
Q45995857Time to fatigue is increased in mouse muscle at 37 degrees C; the role of iron and reactive oxygen species.
Q39363889Trolox enhances curcumin's cytotoxicity through induction of oxidative stress
Q38172265Urinary biomarkers of physical activity: candidates and clinical utility.
Q33616708Vitamin A Oral Supplementation Induces Oxidative Stress and Suppresses IL-10 and HSP70 in Skeletal Muscle of Trained Rats
Q44639002Vitamin C contributes to inflammation via radical generating mechanisms: a cautionary note
Q42460276Vitamin C supplementation does not improve hypoxia-induced erythropoiesis.
Q43254289Vitamin E supplementation decreases muscular and oxidative damage but not inflammatory response induced by eccentric contraction
Q41852089Xiangqing anodyne spray (XQAS): a combination of ethanol extracts of Cynanchum paniculatum and Illicium henryi for treating soft-tissue injury

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