Enhanced proteolysis of IkappaBalpha and IkappaBbeta proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: a potential mechanism of NF-kappaB activation

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Enhanced proteolysis of IkappaBalpha and IkappaBbeta proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: a potential mechanism of NF-kappaB activation is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1008361042
P356DOI10.1080/135502801753170327
P698PubMed publication ID11582519
P5875ResearchGate publication ID251151212

P50authorGeorge StoicaQ43172025
P2093author name stringH T Kim
W Qiang
P K Wong
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The major component of IkappaBalpha proteolysis occurs independently of the proteasome pathway in respiratory syncytial virus-infected pulmonary epithelial cellsQ33784096
Novel IkappaB alpha proteolytic pathway in WEHI231 immature B cellsQ33995197
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I kappa B-beta regulates the persistent response in a biphasic activation of NF-kappa BQ72571349
Up-regulation of the ubiquitin-conjugating and proteolytic systems in murine acquired immunodeficiency syndromeQ73568248
Peroxynitrite formation within the central nervous system in active multiple sclerosisQ74830942
Regulation of human retroviral latency by the NF-kappa B/I kappa B family: inhibition of human immunodeficiency virus replication by I kappa B through a Rev-dependent mechanismQ34624049
Envelope glycoprotein gp120 of human immunodeficiency virus type 1 alters ion transport in astrocytes: implications for AIDS dementia complexQ34979414
Persistent activation of NF-kappa B/Rel by human T-cell leukemia virus type 1 tax involves degradation of I kappa B beta.Q35859739
Moloney murine leukemia virus activates NF-kappa BQ35862437
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In vivo expression of inducible nitric oxide synthase in experimentally induced neurologic diseasesQ36214276
Ubiquitin-dependent degradation of IkappaBalpha is mediated by a ubiquitin ligase Skp1/Cul 1/F-box protein FWD1.Q36453272
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Type C Viruses of Wild Mice: Characterization and Natural History of Amphotropic, Ecotropic, and Xenotropic MuLVQ37773832
Adenovirus vector-induced expression of the C-X-C chemokine IP-10 is mediated through capsid-dependent activation of NF-kappaB.Q38304862
Activation of the ubiquitin proteolytic system in murine acquired immunodeficiency syndrome affects IkappaBalpha turnover.Q38322217
A sustained reduction in IkappaB-beta may contribute to persistent NF-kappaB activation in human endothelial cellsQ38355620
Murine C-type RNA virus from spontaneous neoplasms: in vitro host range and oncogenic potentialQ39351582
Ikappakappa mediates NF-kappaB activation in human immunodeficiency virus-infected cells.Q39550428
Correlation of specific virus-astrocyte interactions and cytopathic effects induced by ts1, a neurovirulent mutant of Moloney murine leukemia virusQ40044159
The I kappa B proteins: multifunctional regulators of Rel/NF-kappa B transcription factorsQ40773951
Regulation of the NF-kappa B/rel transcription factor and I kappa B inhibitor systemQ40835501
Establishment and characterization of conditionally immortalized astrocytes to study their interaction with ts1, a neuropathogenic mutant of Moloney murine leukemia virusQ41129064
Effects on NF-kappa B1/p105 processing of the interaction between the HTLV-1 transactivator Tax and the proteasomeQ41197961
Rel/NF-kappa B transcription factors and the control of apoptosisQ41595442
Activation of transcription factor NF-kappaB by the adenovirus E3/19K protein requires its ER retentionQ41829978
Down-regulation of p27(Kip1) by two mechanisms, ubiquitin-mediated degradation and proteolytic processingQ42816031
High susceptibility of FVB/N mice to the paralytic disease induced by ts1, a mutant of Moloney murine leukemia virus TB.Q44383456
Temporal central and peripheral nervous system changes induced by a paralytogenic mutant of Moloney murine leukemia virus TB.Q44845065
Motor neuronal loss and neurofilament-ubiquitin alteration in MoMuLV-ts1 encephalopathyQ44909443
Herpes simplex type 1 induction of persistent NF-kappa B nuclear translocation increases the efficiency of virus replicationQ45754258
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ts1, a mutant of Moloney murine leukemia virus-TB, causes both immunodeficiency and neurologic disorders in BALB/c miceQ45843494
Neurodegeneration induced by MoMuLV-ts1 and increased expression of Fas and TNF-alpha in the central nervous systemQ48529614
Cytokines regulate L-arginine-dependent cyclic GMP production in rat glial cells.Q55482830
Activation of nuclear factor kB in brains from children with HIV-I encephalitisQ58661964
P433issue5
P921main subjectleukemiaQ29496
proteolysisQ33123
NF-κBQ411114
astrocyteQ502961
murine leukemia virusQ673848
Moloney murine leukemia virusQ61764092
P304page(s)466-475
P577publication date2001-10-01
P1433published inJournal of NeuroVirologyQ6295640
P1476titleEnhanced proteolysis of IkappaBalpha and IkappaBbeta proteins in astrocytes by Moloney murine leukemia virus (MoMuLV)-ts1 infection: a potential mechanism of NF-kappaB activation
P478volume7

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cites work (P2860)
Q44435156Activation of endoplasmic reticulum stress signaling pathway is associated with neuronal degeneration in MoMuLV-ts1-induced spongiform encephalomyelopathy
Q24630229Attenuation of oxidative stress, inflammation and apoptosis by minocycline prevents retrovirus-induced neurodegeneration in mice
Q35149914Effects of mutant ubiquitin on ts1 retrovirus-mediated neuropathology.
Q82505664Interaction between endoplasmic reticulum stress and caspase 8 activation in retrovirus MoMuLV-ts1-infected astrocytes
Q39730979Neuroprotective effects of the drug GVT (monosodium luminol) are mediated by the stabilization of Nrf2 in astrocytes
Q47325446Possible involvement of both endoplasmic reticulum- and mitochondria-dependent pathways in MoMuLV-ts1-induced apoptosis in astrocytes
Q44089254The peroxisome proliferator phenylbutyric acid (PBA) protects astrocytes from ts1 MoMuLV-induced oxidative cell death
Q40394829Up-regulation of astrocyte cyclooxygenase-2, CCAAT/enhancer-binding protein-homology protein, glucose-related protein 78, eukaryotic initiation factor 2 alpha, and c-Jun N-terminal kinase by a neurovirulent murine retrovirus

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