Characteristics and mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes

scientific article published in November 2001

Characteristics and mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0924-8579(01)00430-7
P698PubMed publication ID11711255

P2093author name stringHand WL
Hand DL
P2860cites workAzithromycin inhibition of intracellular Legionella micdadeiQ30451684
Azithromycin pharmacokinetics and intracellular concentrations in Legionella pneumophila-infected and uninfected guinea pigs and their alveolar macrophagesQ33748466
Intracellular activity of azithromycin against bacterial enteric pathogensQ33757644
Uptake, accumulation, and egress of erythromycin by tissue culture cells of human originQ35570335
In vitro and in vivo intraleukocytic accumulation of azithromycin (CP-62, 993) and its influence on ex vivo leukocyte chemiluminescenceQ35862819
Alkalinizing the intralysosomal pH inhibits degranulation of human neutrophilsQ36992519
Description and status of the azithromycin and coronary events study (ACES).Q37876308
Rationale and design of a secondary prevention trial of antibiotic use in patients after myocardial infarction: the WIZARD (weekly intervention with zithromax [azithromycin] for atherosclerosis and its related disorders) trialQ37876312
Randomized secondary prevention trial of azithromycin in patients with coronary artery disease and serological evidence for Chlamydia pneumoniae infection: The Azithromycin in Coronary Artery Disease: Elimination of Myocardial Infection with ChlamydQ37878769
Elevated Chlamydia pneumoniae antibodies, cardiovascular events, and azithromycin in male survivors of myocardial infarctionQ37882420
Influence of pentoxifylline and its derivatives on antibiotic uptake and superoxide generation by human phagocytic cellsQ39780062
Uptake of azithromycin by various cells and its intracellular activity under in vivo conditionsQ39781172
In vitro and in vivo uptake of azithromycin (CP-62,993) by phagocytic cells: possible mechanism of delivery and release at sites of infectionQ39815023
Uptake of antibiotics by human polymorphonuclear leukocyte cytoplastsQ39816249
Effect of phagocyte membrane stimulation on antibiotic uptake and intracellular bactericidal activityQ39828079
Entry of roxithromycin (RU 965), imipenem, cefotaxime, trimethoprim, and metronidazole into human polymorphonuclear leukocytesQ39828887
Contrasts between phagocyte antibiotic uptake and subsequent intracellular bactericidal activityQ39850759
Membrane transport of clindamycin in alveolar macrophagesQ39856468
Antibiotic entry into human polymorphonuclear leukocytesQ39856606
Uptake of azithromycin by human monocytes and enhanced intracellular antibacterial activity against Staphylococcus aureusQ39882462
Interactions of dirithromycin with human polymorphonuclear leukocytesQ39883640
Azithromycin versus ceftriaxone for the treatment of uncomplicated typhoid fever in childrenQ40612317
The effect of azithromycin on intracellular Legionella pneumophila in the Mono Mac 6 cell line at serum concentrations attainable in vivoQ40856037
Advances in the prevention and treatment of Mycobacterium avium disease.Q43603875
Prophylaxis against disseminated Mycobacterium avium complex with weekly azithromycin, daily rifabutin, or both. California Collaborative Treatment GroupQ46670259
Correlation of the extravascular pharmacokinetics of azithromycin with in-vivo efficacy in models of localized infection.Q50467084
Pharmacological considerations in the emergence of resistance.Q54099418
The pharmacokinetics of azithromycin in human serum and tissuesQ68448985
Relationship of high tissue concentrations of azithromycin to bactericidal activity and efficacy in vivoQ68448988
Penetration of macrolides into human polymorphonuclear leucocytesQ69407579
Kinetics of erythromycin uptake and release by human lymphocytes and polymorphonuclear leucocytesQ69620190
The entry of antibiotics into human monocytesQ69679507
Effects of phagocytosis on antibiotic and nucleoside uptake by human polymorphonuclear leukocytesQ71328760
Requirements for intracellular accumulation and release of clarithromycin and azithromycin by human phagocytesQ73230361
The significance of serum vs tissue levels of antibiotics in the treatment of penicillin-resistant Streptococcus pneumoniae and community-acquired pneumonia: are we looking in the wrong place?Q78147690
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectazithromycinQ165399
P304page(s)419-425
P577publication date2001-11-01
P1433published inInternational Journal of Antimicrobial AgentsQ15724616
P1476titleCharacteristics and mechanisms of azithromycin accumulation and efflux in human polymorphonuclear leukocytes
P478volume18