Myopodin is an F-actin bundling protein with multiple independent actin-binding regions.

scientific article published on 9 December 2012

Myopodin is an F-actin bundling protein with multiple independent actin-binding regions. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1044491623
P356DOI10.1007/S10974-012-9334-5
P698PubMed publication ID23225103
P5875ResearchGate publication ID233887718

P50authorKristina Djinovic-CarugoQ56876754
P2093author name stringGregor Kirfel
Dieter O Fürst
Padmanabhan Vakeel
Peter F M van der Ven
Zacharias Orfanos
Eduardo Bezerra
Anja Linnemann
P2860cites workIndications for a novel muscular dystrophy pathway. gamma-filamin, the muscle-specific filamin isoform, interacts with myotilinQ24290423
Protein kinase A, Ca2+/calmodulin-dependent kinase II, and calcineurin regulate the intracellular trafficking of myopodin between the Z-disc and the nucleus of cardiac myocytesQ24296890
Synaptopodin regulates the actin-bundling activity of alpha-actinin in an isoform-specific mannerQ24300368
Promotion of importin alpha-mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3Q24301742
Phosphorylation and interaction of myopodin by integrin-link kinase lead to suppression of cell growth and motility in prostate cancer cellsQ24305936
Myopodin, a synaptopodin homologue, is frequently deleted in invasive prostate cancersQ24633414
Mapping of a myosin-binding domain and a regulatory phosphorylation site in M-protein, a structural protein of the sarcomeric M bandQ24654013
Expression of myopodin induces suppression of tumor growth and metastasisQ24672315
Synaptopodin: an actin-associated protein in telencephalic dendrites and renal podocytesQ24678613
Differentiation- and stress-dependent nuclear cytoplasmic redistribution of myopodin, a novel actin-bundling proteinQ24685429
How to measure and predict the molar absorption coefficient of a proteinQ27860551
Tumor suppressor role for myopodin in bladder cancer: loss of nuclear expression of myopodin is cell-cycle dependent and predicts clinical outcomeQ28201662
Each actin subunit has three nebulin binding sites: implications for steric blockingQ28205447
Vertebrate tropomyosin: distribution, properties and functionQ28216589
Functional properties of non-muscle tropomyosin isoformsQ28252521
Evidence that nebulin is a protein-ruler in muscle thin filamentsQ28278748
CH domains revisitedQ28279947
The sarcomeric Z-disc component myopodin is a multiadapter protein that interacts with filamin and alpha-actininQ28285493
Synaptopodin, a molecule involved in the formation of the dendritic spine apparatus, is a dual actin/alpha-actinin binding proteinQ28303145
Molecular structure of the sarcomeric M band: mapping of titin and myosin binding domains in myomesin and the identification of a potential regulatory phosphorylation site in myomesin.Q28303424
CHAP is a newly identified Z-disc protein essential for heart and skeletal muscle functionQ28588342
The regulation of rabbit skeletal muscle contraction. I. Biochemical studies of the interaction of the tropomyosin-troponin complex with actin and the proteolytic fragments of myosinQ29547591
Xin repeats define a novel actin-binding motif.Q29977766
Xin-repeats and nebulin-like repeats bind to F-actin in a similar mannerQ30439083
Synaptopodin family of natively unfolded, actin binding proteins: physical properties and potential biological functionsQ33639599
Scanning the human proteome for calmodulin-binding proteinsQ33770916
Functional plasticity of CH domains.Q34120320
Disease-associated mutant alpha-actinin-4 reveals a mechanism for regulating its F-actin-binding affinityQ36092522
The molecular mechanism of muscle contraction.Q36288552
Nebulin as a length regulator of thin filaments of vertebrate skeletal muscles: correlation of thin filament length, nebulin size, and epitope profileQ36532856
Novel structural insights into F-actin-binding and novel functions of calponin homology domainsQ37308602
Down-regulation of myopodin expression reduces invasion and motility of PC-3 prostate cancer cells.Q39861963
Titin and nebulin: protein rulers in muscle?Q40566882
Structure-function analysis of the motor domain of myosinQ41275333
Detection and mapping of widespread intermolecular protein disulfide formation during cardiac oxidative stress using proteomics with diagonal electrophoresisQ45005932
Differential involvement of sarcomeric proteins in myofibrillar myopathies: a morphological and immunohistochemical study.Q45061374
Ca2+-calmodulin regulates fesselin-induced actin polymerization.Q45123474
Fesselin is a target protein for calmodulin in a calcium-dependent manner.Q50488046
Diagnostic and prognostic utility of methylation and protein expression patterns of myopodin in colon cancer.Q54328709
Each Actin Subunit Has Three Nebulin Binding SitesQ56593564
Nebulin as a giant actin-binding template protein in skeletal muscle sarcomere. Interaction of actin and cloned human nebulin fragmentsQ70138922
Domain structure of tropomodulin: distinct properties of the N-terminal and C-terminal halvesQ73072354
Fesselin: a novel synaptopodin-like actin binding protein from muscle tissueQ73165971
Myopodin-mediated suppression of prostate cancer cell migration involves interaction with zyxinQ80050798
Smooth muscle alpha-actinin binds tightly to fesselin and attenuates its activity toward actin polymerizationQ82437470
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)61-69
P577publication date2012-12-09
P1433published inJournal of Muscle Research & Cell MotilityQ13739445
P1476titleMyopodin is an F-actin bundling protein with multiple independent actin-binding regions
P478volume34

Reverse relations

cites work (P2860)
Q92732657Assembly and Maintenance of Sarcomere Thin Filaments and Associated Diseases
Q37384926Avian synaptopodin 2 (fesselin) stabilizes myosin filaments and actomyosin in the presence of ATP.
Q38427624Identification of cardiac myofilament protein isoforms using multiple mass spectrometry based approaches
Q38724052Myofibrillar Z-discs Are a Protein Phosphorylation Hot Spot with Protein Kinase C (PKCα) Modulating Protein Dynamics
Q30411778Organization of F-actin by Fesselin (avian smooth muscle synaptopodin 2).
Q39391006Overview of the Muscle Cytoskeleton
Q30655968Synaptopodin-2 induces assembly of peripheral actin bundles and immature focal adhesions to promote lamellipodia formation and prostate cancer cell migration

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