On the behavioural specificity of hypophagia induced in male rats by mCPP, naltrexone, and their combination

scientific article published on 11 October 2013

On the behavioural specificity of hypophagia induced in male rats by mCPP, naltrexone, and their combination is …
instance of (P31):
scholarly articleQ13442814

External links are
P6179Dimensions Publication ID1037726204
P356DOI10.1007/S00213-013-3295-2
P698PubMed publication ID24114428

P2093author name stringR J Rodgers
F L Wright
P2860cites workLeptin responsiveness restored by amylin agonism in diet-induced obesity: evidence from nonclinical and clinical studiesQ24650977
Evidence that mCPP may have behavioural effects mediated by central 5-HT1C receptorsQ24681893
A review of central 5-HT receptors and their functionQ28142963
International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (Serotonin)Q28239487
Chlorophenylpiperazine: a central serotonin agonist causing powerful anorexia in ratsQ28249545
5-HT2C receptor activation decreases appetite and body weight in obese subjectsQ28253985
Anxiogenic-like effects of mCPP and TFMPP in animal models are opposed by 5-HT1C receptor antagonistsQ28278816
Serotonergic drugs : effects on appetite expression and use for the treatment of obesityQ28282364
Evidence that hypophagia induced by mCPP and TFMPP requires 5-HT1C and 5-HT1B receptors; hypophagia induced by RU 24969 only requires 5-HT1B receptorsQ28284027
m-Chlorophenylpiperazine decreases food intake in a test mealQ28307494
'Liking' and 'wanting' food rewards: brain substrates and roles in eating disordersQ30489108
Synergistic efects of opioid and cannabinoid antagonists on food intakeQ32014540
SB-334867, a selective orexin-1 receptor antagonist, enhances behavioural satiety and blocks the hyperphagic effect of orexin-A in ratsQ33942180
The tempted brain eats: pleasure and desire circuits in obesity and eating disordersQ34032576
New approaches to the pharmacological treatment of obesity: can they break through the efficacy barrier?Q34129885
Dose combinations of exendin-4 and salmon calcitonin produce additive and synergistic reductions in food intake in nonhuman primatesQ34150227
Mechanisms underlying current and future anti-obesity drugsQ34322175
Central serotonin and melanocortin pathways regulating energy homeostasisQ35173358
The utility of animal models to evaluate novel anti-obesity agentsQ35589958
Two-year sustained weight loss and metabolic benefits with controlled-release phentermine/topiramate in obese and overweight adults (SEQUEL): a randomized, placebo-controlled, phase 3 extension studyQ35677262
Endogenous opioids and feeding behavior: a 30-year historical perspectiveQ35785708
The 5-HT2C receptor agonist lorcaserin reduces nicotine self-administration, discrimination, and reinstatement: relationship to feeding behavior and impulse controlQ35837700
Inhibition of opioid transmission at the μ-opioid receptor prevents both food seeking and binge-like eatingQ36323534
Enhanced weight loss with pramlintide/metreleptin: an integrated neurohormonal approach to obesity pharmacotherapyQ37368085
From taste hedonics to motivational drive: central μ-opioid receptors and binge-eating behaviourQ37477414
Contrave, a bupropion and naltrexone combination therapy for the potential treatment of obesityQ37602626
"Weighing in" on synergy: preclinical research on neurohormonal anti-obesity combinationsQ37680204
Behavioural satiety sequence (BSS): separating wheat from chaff in the behavioural pharmacology of appetiteQ37705616
Pharmacological management of appetite expression in obesityQ37710372
CNS regulation of appetiteQ37982153
What is the prognosis for new centrally-acting anti-obesity drugs?Q37982154
Animal models to explore the effects of CNS drugs on food intake and energy expenditureQ38019751
Anti-obesity drugs: past, present and futureQ38036925
Effects of naltrexone on food preference and concurrent behavioral responses in food-deprived ratsQ39222042
Night and day: diurnal differences in the behavioural satiety sequence in male ratsQ39981929
Endogenous Pain Control Systems: Brainstem Spinal Pathways and Endorphin CircuitryQ40093729
Multiple serotonin receptors: opportunities for new treatments for obesity?Q41026153
Effects of naloxone and naltrexone on meal patterns of freely-feeding ratsQ41456198
Sibutramine & naloxone: infra-additive interaction in the regulation of appetite?Q43264198
Synergy of sibutramine and low-dose leptin in treatment of diet-induced obesity in ratsQ43688883
A new glucagon and GLP-1 co-agonist eliminates obesity in rodentsQ43756107
Effects of the cannabinoid receptor antagonist SR 141716, alone and in combination with dexfenfluramine or naloxone, on food intake in ratsQ43858350
Serotonin 2C receptor agonists and the behavioural satiety sequence in mice.Q43913101
Effect of opioid and cannabinoid receptor antagonism on orphanin FQ-induced hyperphagia in ratsQ44028213
Activation of central melanocortin pathways by fenfluramineQ44079737
Long-term weight control study. I (weeks 0 to 34). The enhancement of behavior modification, caloric restriction, and exercise by fenfluramine plus phentermine versus placeboQ44222626
Interaction between opioid agonists or naloxone and 5-HTP on feeding behavior in food-deprived ratsQ44349012
Palatability, food intake and the behavioural satiety sequence in male ratsQ44624775
Differential effects of the selective orexin-1 receptor antagonist SB-334867 and lithium chloride on the behavioural satiety sequence in ratsQ44826752
Reduced hypophagic effects of d-fenfluramine and the 5-HT2C receptor agonist mCPP in 5-HT1B receptor knockout miceQ44892908
Evaluation of chemically diverse 5-HT₂c receptor agonists on behaviours motivated by food and nicotine and on side effect profilesQ46240693
Rational design of a combination medication for the treatment of obesityQ46255375
Effects of acute low-dose combined treatment with naloxone and AM 251 on food intake, feeding behaviour and weight gain in ratsQ46405494
Peripheral exendin-4 and peptide YY(3-36) synergistically reduce food intake through different mechanisms in miceQ46525214
Antiobesity effects of the beta-cell hormone amylin in combination with phentermine or sibutramine in diet-induced obese ratsQ46535152
Endogenous opioids and cannabinoids: system interactions in the regulation of appetite, grooming and scratchingQ46659888
Effects of a Cannabinoid1 receptor antagonist and Serotonin2C receptor agonist alone and in combination on motivation for palatable food: a dose-addition analysis study in miceQ46767789
Combination therapy of zonisamide and bupropion for weight reduction in obese women: a preliminary, randomized, open-label study.Q47270495
Combination therapy with amylin and peptide YY[3-36] in obese rodents: anorexigenic synergy and weight loss additivityQ47272388
Randomized placebo-controlled clinical trial of lorcaserin for weight loss in type 2 diabetes mellitus: the BLOOM-DM studyQ47321369
Combined stimulation of glucagon-like peptide-1 receptor and inhibition of cannabinoid CB1 receptor act synergistically to reduce food intake and body weight in the rat.Q47342941
Effects of exendin-4 alone and with peptide YY(3-36) on food intake and body weight in diet-induced obese ratsQ47427740
5-HT(2C) receptor activation inhibits appetitive and consummatory components of feeding and increases brain c-fos immunoreactivity in mice.Q48140056
Combined injection potentiates the satiety effects of pancreatic glucagon, cholecystokinin, and bombesin.Q48278684
Effects of food deprivation and mCPP treatment on the microstructure of ingestive behaviour of male and female ratsQ48348417
Brainstem sensing of meal-related signals in energy homeostasisQ48575606
Combined naloxone and fluoxetine on deprivation-induced binge eating of palatable foods in ratsQ48734137
Effect of hypothalamic and peripheral fluoxetine injection on natural patterns of macronutrient intake in the ratQ48805783
Behavioral mechanisms for the anorectic action of the serotonin (5-HT) uptake inhibitor sertraline in rats: comparison with directly acting 5-HT agonistsQ48848141
m-Chlorophenylpiperazine enhances neophobic and anxious behaviour in miceQ48862784
Naloxone and serotonin receptor subtype antagonists: interactive effects upon deprivation-induced intakeQ48874896
Dual action of naloxone on feeding revealed by behavioural analysis: separate effects on initiation and termination of eatingQ49022242
Effects of RO 60 0175, a 5-HT(2C) receptor agonist, in three animal models of anxiety.Q51083229
Effects of systematic variation in presatiation and fasting on the behavioural satiety sequence in male rats.Q51535635
Behavioral satiety sequence (BSS) for the diagnosis of drug action on food intake.Q52531846
Acute behavioural effects of bupropion and naltrexone, alone and in combination, in non-deprived male rats presented with palatable mash.Q52638749
Behaviourally-selective hypophagic effects of naloxone in non-deprived male rats presented with palatable food.Q52852561
Anxiogenic-like effects of fluprazine and eltoprazine in the mouse elevated plus-maze: profile comparisons with 8-OH-DPAT, CGS 12066B, TFMPP and mCPP.Q52873443
Effect of naloxone and naltrexone on the development of satiation measured in the runway: comparisons with d-amphetamine and d-fenfluramine.Q52943295
The effects of 5-HT1B characterizing agents in the mouse elevated plus-maze.Q54102296
Combination pharmaceutical therapies for obesityQ57314317
Serotonin Reciprocally Regulates Melanocortin Neurons to Modulate Food IntakeQ57912931
Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist, and d-fenfluramine on feeding patterns in the ratQ60054744
An examination of the behavioural specificity of hypophagia induced by 5-HT1B, 5-HT1C and 5-HT2 receptor agonists using the post-prandial satiety sequence in ratsQ60054753
5-HT1B agonists induce anorexia at a postsynaptic siteQ60054778
Paraventricular nucleus controls 5-HT2C receptor-mediated corticosterone and prolactin but not oxytocin and penile erection responsesQ60710700
Effect of 5-HT1C and 5-HT2 receptor stimulation on excessive grooming, penile erection and plasma oxytocin concentrationsQ60710714
Synergy between amylin and cholecystokinin for inhibition of food intake in miceQ77372246
Interactions between leptin and exendin-4, a glucagon-like peptide-1 agonist, in the regulation of food intake in the ratQ80593655
P433issue4
P921main subjectnaltrexoneQ409587
P1104number of pages14
P304page(s)787-800
P577publication date2013-10-11
P1433published inPsychopharmacologyQ1422802
P1476titleOn the behavioural specificity of hypophagia induced in male rats by mCPP, naltrexone, and their combination
P478volume231

Reverse relations

cites work (P2860)
Q27347643Attention bias to threat indicates anxiety differences in sheep.
Q51744991Behavioural profile of exendin-4/naltrexone dose combinations in male rats during tests of palatable food consumption.
Q93093150Effects of early and later life environmental enrichment and personality on attention bias in pigs (Sus scrofa domesticus)
Q36402156Evaluating pharmacological models of high and low anxiety in sheep
Q47738255Evidence for a role of 5-HT2C receptors in the motor aspects of performance, but not the efficacy of food reinforcers, in a progressive ratio schedule.
Q39059417Subchronic administration of short-acting naltrexone has no effect on striatal dopamine transporter availability, food intake or body weight gain in rats
Q47223800Towards a more practical attention bias test to assess affective state in sheep.

Search more.