Gene therapy of gastric cancer using LIGHT-secreting human umbilical cord blood-derived mesenchymal stem cells

scientific article published in August 2012

Gene therapy of gastric cancer using LIGHT-secreting human umbilical cord blood-derived mesenchymal stem cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1007/S10120-012-0166-1
P698PubMed publication ID22850801
P5875ResearchGate publication ID230592183

P2093author name stringDongqi Tang
Dongming Su
Tongyun Liu
Chenfang Dong
Shiying Xuan
Zhenbo Dai
Xinhong Zhu
Weizheng Mao
Guiliang Ma
P2860cites workNK-cell activation by LIGHT triggers tumor-specific CD8+ T-cell immunity to reject established tumorsQ35848615
Attenuated Salmonella engineered to produce human cytokine LIGHT inhibit tumor growthQ35921725
Targeting tumors with LIGHT to generate metastasis-clearing immunityQ37175025
Adenovirus-mediated LIGHT gene modification in murine B-cell lymphoma elicits a potent antitumor effectQ37729679
CXC chemokine receptor 1 enhances the ability of human umbilical cord blood-derived mesenchymal stem cells to migrate toward gliomasQ39570178
Gene therapy using TRAIL-secreting human umbilical cord blood-derived mesenchymal stem cells against intracranial gliomaQ39910399
Bystander killing of malignant glioma by bone marrow-derived tumor-infiltrating progenitor cells expressing a suicide geneQ40141485
Tumor vaccine based on cell surface expression of DcR3/TR6.Q40437961
Stored placental blood for unrelated bone marrow reconstitutionQ40708879
Modulation of T-cell-mediated immunity in tumor and graft-versus-host disease models through the LIGHT co-stimulatory pathwayQ40896166
Antibodies to TR2 (herpesvirus entry mediator), a new member of the TNF receptor superfamily, block T cell proliferation, expression of activation markers, and production of cytokines.Q41015040
Approaches to utilize mesenchymal progenitor cells as cellular vehiclesQ44495575
Comparison of the anti-tumor activity of native, secreted, and membrane-bound LIGHT in mouse tumor modelsQ44508375
CXCR4-transfected human umbilical cord blood-derived mesenchymal stem cells exhibit enhanced migratory capacity toward gliomasQ45865276
Antitumor effect of genetically engineered mesenchymal stem cells in a rat glioma modelQ45875290
Characterization and gene transfer in mesenchymal stem cells derived from human umbilical-cord bloodQ45887902
Human bone marrow-derived mesenchymal stem cells in the treatment of gliomasQ48926056
Bone marrow-derived mesenchymal stem cells as vehicles for interferon-beta delivery into tumorsQ64378688
LIGHT, a TNF-like molecule, costimulates T cell proliferation and is required for dendritic cell-mediated allogeneic T cell responseQ73644490
Mouse T cells receive costimulatory signals from LIGHT, a TNF family memberQ78385817
Gastric cancer--new therapeutic optionsQ79844903
Re: Mesenchymal stem cells: potential precursors for tumor stroma and targeted-delivery vehicles for anticancer agentsQ81616464
A newly identified member of tumor necrosis factor receptor superfamily (TR6) suppresses LIGHT-mediated apoptosisQ22009531
LIGHT, a new member of the TNF superfamily, and lymphotoxin alpha are ligands for herpesvirus entry mediatorQ24308657
LIGHT, a novel ligand for lymphotoxin beta receptor and TR2/HVEM induces apoptosis and suppresses in vivo tumor formation via gene transferQ24564377
Global cancer statistics, 2002Q27860562
A TNF family member LIGHT transduces costimulatory signals into human T cellsQ28216861
Comparative analysis of mesenchymal stem cells from bone marrow, umbilical cord blood, or adipose tissueQ29620725
Bone marrow stromal cells as targets for gene therapyQ34729629
CXCR4/SDF-1 axis is involved in lymph node metastasis of gastric carcinomaQ35012653
MMP-2 mediates mesenchymal stem cell tropism towards medulloblastoma tumorsQ35069593
Neural stem cells display extensive tropism for pathology in adult brain: evidence from intracranial gliomasQ35827956
P433issue2
P921main subjectgene therapyQ213901
human umbilical cord mesenchymal stem cellQ107296600
P304page(s)155-166
P577publication date2012-08-01
P1433published inGastric CancerQ15724608
P1476titleGene therapy of gastric cancer using LIGHT-secreting human umbilical cord blood-derived mesenchymal stem cells
P478volume16

Reverse relations

cites work (P2860)
Q38226664Cells as delivery vehicles for cancer therapeutics
Q94526850Efficacy of mesenchymal stem cells in the treatment of gastrointestinal malignancies
Q42391294Engineered Mesenchymal Stem Cells as an Anti-Cancer Trojan Horse
Q98159785Evaluation of the expression of bone marrow-derived mesenchymal stem cells and cancer-associated fibroblasts in the stroma of gastric cancer tissue
Q27002840Gastric cancer stem cells: a novel therapeutic target
Q26853431Immunotherapeutic organoids: a new approach to cancer treatment
Q35549931Large-scale expansion of Wharton's jelly-derived mesenchymal stem cells on gelatin microbeads, with retention of self-renewal and multipotency characteristics and the capacity for enhancing skin wound healing
Q35159519Mesenchymal stem cells expressing interleukin-18 suppress breast cancer cells in vitro
Q38761193Opposite Effects of Coinjection and Distant Injection of Mesenchymal Stem Cells on Breast Tumor Cell Growth
Q26799123Therapeutic Lymphoid Organogenesis in the Tumor Microenvironment
Q50594290VEGF Enhances the Migration of MSCs in Neural Differentiation by Regulating Focal Adhesion Turnover.
Q42368100pIL6-TRAIL-engineered umbilical cord mesenchymal/stromal stem cells are highly cytotoxic for myeloma cells both in vitro and in vivo

Search more.