Exercise training improves muscle insulin resistance but not insulin receptor signaling in obese Zucker rats

scientific article published in February 2002

Exercise training improves muscle insulin resistance but not insulin receptor signaling in obese Zucker rats is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/JAPPLPHYSIOL.00784.2001
P8608Fatcat IDrelease_ih7sovrp5bedphrneie3ceacja
P698PubMed publication ID11796688
P5875ResearchGate publication ID11561574

P50authorLawrence J MandarinoQ91188766
P2093author name stringJohn L Ivy
Desmond Hunt
Rebeca Garcia-Macedo
Christine Y Christ
Joe Hancock
P2860cites workSkeletal muscle glucose transport in obese Zucker rats after exercise training.Q54352096
Exercise and diet reduce muscle insulin resistance in obese Zucker rat.Q54422982
CAP defines a second signalling pathway required for insulin-stimulated glucose transportQ24290287
Insulin-stimulated GLUT4 translocation requires the CAP-dependent activation of TC10Q24291135
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Exercise training increases ERK2 activity in skeletal muscle of obese Zucker ratsQ31837648
Normal insulin-dependent activation of Akt/protein kinase B, with diminished activation of phosphoinositide 3-kinase, in muscle in type 2 diabetesQ33853693
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) ratsQ33857313
Fiber type-specific expression of GLUT4 in human skeletal muscle: influence of exercise trainingQ33911140
Insulin resistance in obese Zucker rat (fa/fa) skeletal muscle is associated with a failure of glucose transporter translocationQ35607407
Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistanceQ35608446
Exercise-induced changes in expression and activity of proteins involved in insulin signal transduction in skeletal muscle: differential effects on insulin-receptor substrates 1 and 2.Q37141138
Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscleQ37175187
Insulin resistance in soleus muscle from obese Zucker rats. Involvement of several defective sitesQ42107369
Exercise training reverses insulin resistance in muscle by enhanced recruitment of GLUT-4 to the cell surface.Q42439219
An inhibitor of p38 mitogen-activated protein kinase prevents insulin-stimulated glucose transport but not glucose transporter translocation in 3T3-L1 adipocytes and L6 myotubesQ42470059
Effects of exercise training on muscle GLUT-4 protein content and translocation in obese Zucker ratsQ42501861
Glucose transport: locus of muscle insulin resistance in obese Zucker ratsQ43608464
Insulin effect during embryogenesis determines fetal growth: a possible molecular link between birth weight and susceptibility to type 2 diabetesQ47250275
Leptin receptor missense mutation in the fatty Zucker rat.Q48064469
Effect of short-term exercise training on insulin-stimulated PI 3-kinase activity in human skeletal muscle.Q51559328
Altered expression levels and impaired steps in the pathway to phosphatidylinositol 3-kinase activation via insulin receptor substrates 1 and 2 in Zucker fatty rats.Q54150649
Glucose uptake and GLUT-4 protein distribution in skeletal muscle of the obese Zucker rat.Q54199501
Insulin resistance of obese Zucker rats exercise trained at two different intensities.Q54284806
P433issue2
P407language of work or nameEnglishQ1860
P921main subjectinsulin resistanceQ1053470
obesityQ12174
preproinsulinQ7240673
P304page(s)736-744
P577publication date2002-02-01
P1433published inJournal of Applied PhysiologyQ1091719
P1476titleExercise training improves muscle insulin resistance but not insulin receptor signaling in obese Zucker rats
P478volume92

Reverse relations

cites work (P2860)
Q28393888A 6-week training program increased muscle antioxidant system in elderly diabetic fatty rats
Q41833222A Novel Wistar Rat Model of Obesity-Related Nonalcoholic Fatty Liver Disease Induced by Sucrose-Rich Diet
Q37251400A chronic increase in physical activity inhibits fed-state mTOR/S6K1 signaling and reduces IRS-1 serine phosphorylation in rat skeletal muscle.
Q33762975Altered regulation of contraction-induced Akt/mTOR/p70S6k pathway signaling in skeletal muscle of the obese Zucker rat.
Q36983863Circulating adiponectin and adiponectin receptor expression in skeletal muscle: effects of exercise
Q51753962Circulating lipids are lowered but pancreatic islet lipid metabolism and insulin secretion are unaltered in exercise-trained female rats.
Q45291507Contraction activates glucose uptake and glycogen synthase normally in muscles from dexamethasone-treated rats.
Q38162296Coupling physical exercise with dietary glucose supplement for treating cognitive impairment in schizophrenia: a theoretical model and future directions
Q36694006Diabetes alters contraction-induced mitogen activated protein kinase activation in the rat soleus and plantaris
Q35607527Differential effects of acute (extenuating) and chronic (training) exercise on inflammation and oxidative stress status in an animal model of type 2 diabetes mellitus
Q38007405Effects of glucocorticoids and exercise on pancreatic β-cell function and diabetes development
Q46265962Effects of treadmill exercise on cell proliferation and differentiation in the subgranular zone of the dentate gyrus in a rat model of type II diabetes
Q45142910Endurance exercise training increases insulin responsiveness in isolated adipocytes through IRS/PI3-kinase/Akt pathway
Q42464125Exercise maintains euglycemia in association with decreased activation of c-Jun NH2-terminal kinase and serine phosphorylation of IRS-1 in the liver of ZDF rats
Q58449847Exercise training increases insulin-stimulated glucose disposal and GLUT4 (SLC2A4) protein content in patients with type 2 diabetes
Q37188040Head to Head Comparison of Short-Term Treatment with the NAD(+) Precursor Nicotinamide Mononucleotide (NMN) and 6 Weeks of Exercise in Obese Female Mice.
Q44543791Increased insulin receptor signaling and glycogen synthase activity contribute to the synergistic effect of exercise on insulin action
Q36340697Insulin receptor and IRS-1 co-immunoprecipitation with SOCS-3, and IKKα/β phosphorylation are increased in obese Zucker rat skeletal muscle
Q34754988Invited review: Effects of acute exercise and exercise training on insulin resistance
Q33579865Lean and obese Zucker rats exhibit different patterns of p70s6 kinase regulation in the tibialis anterior muscle in response to high-force muscle contraction
Q45073976Mediation of beta-endorphin in exercise-induced improvement in insulin resistance in obese Zucker rats
Q28581219Metformin and exercise reduce muscle FAT/CD36 and lipid accumulation and blunt the progression of high-fat diet-induced hyperglycemia
Q43493439Nicotinamide mononucleotide (NMN) supplementation ameliorates the impact of maternal obesity in mice: comparison with exercise.
Q35671734Resistance training associated with the administration of anabolic-androgenic steroids improves insulin sensitivity in ovariectomized rats.
Q36196044Swim Training Improves HOMA-IR in Type 2 Diabetes Induced by High Fat Diet and Low Dose of Streptozotocin in Male Rats.
Q42521678Swim training prevents hyperglycemia in ZDF rats: mechanisms involved in the partial maintenance of beta-cell function
Q51346853The Effect of Early Intensive Insulin Therapy on Body Fat Distribution and β-Cell Function in Newly Diagnosed Type 2 Diabetes.
Q36825634The effect of exercise, training, and inactivity on insulin sensitivity in diabetics and their relatives: what is new?
Q44733458The effect of insulin and exercise on c-Cbl protein abundance and phosphorylation in insulin-resistant skeletal muscle in lean and obese Zucker rats
Q35642128The role of skeletal muscle glycogen breakdown for regulation of insulin sensitivity by exercise
Q45271860Voluntary exercise training enhances glucose transport but not insulin signaling capacity in muscle of hypertensive TG(mREN2)27 rats
Q38922349α-Linolenic acid supplementation and exercise training reveal independent and additive responses on hepatic lipid accumulation in obese rats

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