Loss of lymphotoxin-alpha but not tumor necrosis factor-alpha reduces atherosclerosis in mice

scientific article published on 23 January 2002

Loss of lymphotoxin-alpha but not tumor necrosis factor-alpha reduces atherosclerosis in mice is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111727200
P698PubMed publication ID11809756

P2093author name stringRenée C LeBoeuf
Cynthia M Vick
Sandra A Schreyer
P2860cites workLymphotoxin beta, a novel member of the TNF family that forms a heteromeric complex with lymphotoxin on the cell surfaceQ24320309
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cellsQ28119154
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin ResistanceQ28131660
Ath-1, a gene determining atherosclerosis susceptibility and high density lipoprotein levels in miceQ28505210
Abnormal development of peripheral lymphoid organs in mice deficient in lymphotoxinQ28507630
Mice deficient for the 55 kd tumor necrosis factor receptor are resistant to endotoxic shock, yet succumb to L. monocytogenes infectionQ28509078
RAG-1-deficient mice have no mature B and T lymphocytesQ28592133
Mice lacking the tumour necrosis factor receptor 1 are resistant to TNF-mediated toxicity but highly susceptible to infection by Listeria monocytogenesQ28593744
Decreased sensitivity to tumour-necrosis factor but normal T-cell development in TNF receptor-2-deficient miceQ28593915
The transmembrane form of tumor necrosis factor is the prime activating ligand of the 80 kDa tumor necrosis factor receptorQ28610826
Dissection of TNF receptor 1 effector functions: JNK activation is not linked to apoptosis while NF-kappaB activation prevents cell deathQ29620021
Tumor necrosis factor receptor and Fas signaling mechanisms.Q33652491
Monocyte chemoattractant protein-1 but not tumor necrosis factor-alpha is correlated with monocyte infiltration in mouse lipid lesionsQ33860523
Signaling through the lymphotoxin beta receptor induces the death of some adenocarcinoma tumor linesQ34381306
T and B lymphocytes play a minor role in atherosclerotic plaque formation in the apolipoprotein E-deficient mouseQ36142970
A critical role for lymphotoxin in experimental allergic encephalomyelitisQ36380767
Quantitative assessment of atherosclerotic lesions in miceQ36456167
Increased atherosclerosis in streptozotocin-induced diabetic miceQ37353969
The effects of total lymphocyte deficiency on the extent of atherosclerosis in apolipoprotein E-/- miceQ37372718
The Role of Tumor Necrosis Factor-α Receptors in AtherosclerosisQ37828682
The biology of cachectin/TNF--a primary mediator of the host responseQ38269386
Tumor necrosis factor alpha (TNF-alpha)-induced cell adhesion to human endothelial cells is under dominant control of one TNF receptor type, TNF-R55.Q38319685
Tumor necrosis factor's cytotoxic activity is signaled by the p55 TNF receptorQ40853190
Lymphotoxin-alpha is an autocrine growth factor for chronic lymphocytic leukemia B cellsQ41049086
Induction of apoptosis in mature T cells by tumour necrosis factorQ41293478
Lymphotoxin alpha-/- mice develop functionally impaired CD8+ T cell responses and fail to contain virus infection of the central nervous systemQ45739093
Detection and localization of tumor necrosis factor in human atheromaQ46152807
C57BL/6 mice fed high fat diets as models for diabetes-accelerated atherosclerosis.Q51570758
P433issue14
P407language of work or nameEnglishQ1860
P921main subjectatherosclerosisQ12252367
P1104number of pages5
P304page(s)12364-12368
P577publication date2002-01-23
P1433published inJournal of Biological ChemistryQ867727
P1476titleLoss of lymphotoxin-alpha but not tumor necrosis factor-alpha reduces atherosclerosis in mice
P478volume277

Reverse relations

cites work (P2860)
Q46945717A functional polymorphism in the lymphotoxin-alpha gene is associated with carotid artery wall thickness: the Diabetes Heart Study
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Q46562417Association of the lymphotoxin-alpha gene Thr26Asn polymorphism with severity of coronary atherosclerosis.
Q26739070Cardiovascular risk assessment in patients with rheumatoid arthritis: The relevance of clinical, genetic and serological markers
Q49335652Correlations of chemokine CXCL16 and TNF-α with coronary atherosclerotic heart disease
Q44436182Cross-sectional study of risk factors for atherosclerosis in the Azorean population.
Q37071164Cyclooxygenase products and atherosclerosis
Q36802942Cytokines and atherosclerosis: a comprehensive review of studies in mice
Q31124912Data on gene and protein expression changes induced by apabetalone (RVX-208) in ex vivo treated human whole blood and primary hepatocytes
Q35900629Deficiency of lymphotoxin-α does not exacerbate high-fat diet-induced obesity but does enhance inflammation in mice
Q39645825Deletion of P2Y2 receptor reveals a role for lymphotoxin-α in fatty streak formation
Q34763602Deletion of the p66Shc longevity gene reduces systemic and tissue oxidative stress, vascular cell apoptosis, and early atherogenesis in mice fed a high-fat diet.
Q47140191Elucidation of Gene Expression Patterns in the Brain after Spinal Cord Injury.
Q46434986Free cholesterol-loaded macrophages are an abundant source of tumor necrosis factor-alpha and interleukin-6: model of NF-kappaB- and map kinase-dependent inflammation in advanced atherosclerosis
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Q33292125Functional variation in LGALS2 confers risk of myocardial infarction and regulates lymphotoxin-alpha secretion in vitro
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