Interaction between sulthiame and clobazam: sulthiame inhibits the metabolism of clobazam, possibly via an action on CYP2C19.

scientific article published on 17 April 2014

Interaction between sulthiame and clobazam: sulthiame inhibits the metabolism of clobazam, possibly via an action on CYP2C19. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.YEBEH.2014.03.018
P698PubMed publication ID24742983

P2093author name stringYoshiaki Yamamoto
Yukitoshi Takahashi
Yushi Inoue
Kazumi Matsuda
Yoshiyuki Kagawa
Katsumi Imai
Yukiko Mogami
Masahiko Nakai
P2860cites workStiripentol in severe myoclonic epilepsy in infancy: a randomised placebo-controlled syndrome-dedicated trial. STICLO study groupQ28138394
Sulthiame (Ospolot) as inhibitor of diphenylhydatoin metabolism.Q34208762
Inhibition of phenytoin metabolism by sulthiame in epileptic patientsQ34451296
Phenytoin intoxication induced by sulthiame in epileptic patientsQ37097628
Sulthiame in refractory paediatric epilepsies: an experience of an 'old' antiepileptic drug in a tertiary paediatric neurology unit.Q37933761
Stiripentol open study in Japanese patients with Dravet syndromeQ42625679
Impact of CYP2C19 polymorphisms on the efficacy of clobazam therapyQ46605318
Sulthiame therapy for continuous spike and wave in slow-wave sleepQ48491640
Influence of CYP2C19 polymorphism and concomitant antiepileptic drugs on serum clobazam and N-desmethyl clobazam concentrations in patients with epilepsy.Q51000131
Benign partial epilepsy--treatment with sulthiameQ69930570
Efficacy of low-dose, add-on therapy of clobazam (CLB) is produced by its major metabolite, N-desmethyl-CLBQ80519547
P304page(s)124-126
P577publication date2014-04-17
P1433published inEpilepsy BehaviorQ15746410
P1476titleInteraction between sulthiame and clobazam: sulthiame inhibits the metabolism of clobazam, possibly via an action on CYP2C19.
P478volume34

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cites work (P2860)
Q53835626Drug-drug interaction between clobazam and cannabidiol in children with refractory epilepsy.
Q52667006PharmGKB summary: clobazam pathway, pharmacokinetics.
Q36365500Pharmacogenetics of drug-drug interaction and drug-drug-gene interaction: a systematic review on CYP2C9, CYP2C19 and CYP2D6.
Q90020510Pharmacokinetics and Drug Interaction of Antiepileptic Drugs in Children and Adolescents

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