| scholarly article | Q13442814 |
| P50 | author | Michael Karin | Q1458081 |
| P2093 | author name string | Gary S Firestein | |
| Lufen Chang | |||
| Zuoning Han | |||
| Yuji Yamanishi | |||
| P2860 | cites work | c-Jun N-terminal kinase is required for metalloproteinase expression and joint destruction in inflammatory arthritis | Q28343409 |
| JNK is required for effector T-cell function but not for T-cell activation | Q28507174 | ||
| AP-1 function and regulation | Q29618422 | ||
| Signal transduction and transcription factors in rheumatic disease | Q33598827 | ||
| JNK2 is required for efficient T-cell activation and apoptosis but not for normal lymphocyte development. | Q54105156 | ||
| Collagen-induced arthritis in mice: synergistic effect of E. coli lipopolysaccharide bypasses epitope specificity in the induction of arthritis with monoclonal antibodies to type II collagen | Q71333516 | ||
| Integration of the NF-kappaB and mitogen-activated protein kinase/AP-1 pathways at the collagenase-1 promoter: divergence of IL-1 and TNF-dependent signal transduction in rabbit primary synovial fibroblasts | Q73053416 | ||
| Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthr | Q73202432 | ||
| Isoforms of Jun kinase are differentially expressed and activated in human monocyte/macrophage (THP-1) cells | Q73785419 | ||
| Human interleukin-17: A T cell-derived proinflammatory cytokine produced by the rheumatoid synovium | Q77738643 | ||
| AP-1 and NF-kappaB regulation in rheumatoid arthritis and murine collagen-induced arthritis | Q77805751 | ||
| P433 | issue | 3 | |
| P921 | main subject | knockout mouse | Q1364740 |
| P304 | page(s) | 818-823 | |
| P577 | publication date | 2002-03-01 | |
| P1433 | published in | Arthritis & Rheumatology | Q4797636 |
| P1476 | title | Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis | |
| P478 | volume | 46 |
| Q33892441 | Acid-sensing ion channel 3 decreases phosphorylation of extracellular signal-regulated kinases and induces synoviocyte cell death by increasing intracellular calcium |
| Q36794528 | Acid-sensing ion channel 3 deficiency increases inflammation but decreases pain behavior in murine arthritis |
| Q36718541 | Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis |
| Q36836817 | Are MAP kinases drug targets? Yes, but difficult ones |
| Q31017238 | Collagen type II-specific monoclonal antibody-induced arthritis in mice: description of the disease and the influence of age, sex, and genes |
| Q27676927 | Discovery of Potent and Selective Covalent Inhibitors of JNK |
| Q24801037 | Effect of phospholipase A2 inhibitory peptide on inflammatory arthritis in a TNF transgenic mouse model: a time-course ultrastructural study |
| Q29618020 | Evolving concepts of rheumatoid arthritis |
| Q92712478 | Fibroblast-Like Synoviocytes Glucose Metabolism as a Therapeutic Target in Rheumatoid Arthritis |
| Q34254458 | Identification of NURR1 as a mediator of MIF signaling during chronic arthritis: effects on glucocorticoid-induced MKP1 |
| Q35190872 | Increased sensitivity to apoptosis induced by methotrexate is mediated by JNK. |
| Q24815106 | Inhibitors of mitogen-activated protein kinases downregulate COX-2 expression in human chondrocytes |
| Q84504239 | Inhibitory effect of the antimalarial agent artesunate on collagen-induced arthritis in rats through nuclear factor kappa B and mitogen-activated protein kinase signaling pathway |
| Q55034856 | Interleukin-21 induces migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis. |
| Q38097866 | JNK inhibitors as anti-inflammatory and neuroprotective agents |
| Q35822826 | JNK pathway signaling: a novel and smarter therapeutic targets for various biological diseases. |
| Q35019433 | JNK-1 deficiency limits macrophage-mediated antigen-induced arthritis |
| Q34438110 | JNK1 controls mast cell degranulation and IL-1{beta} production in inflammatory arthritis |
| Q24799357 | JNK1 is not essential for TNF-mediated joint disease |
| Q38575671 | JNK1, but not JNK2, is required in two mechanistically distinct models of inflammatory arthritis |
| Q37030862 | Metalloproteases as potential therapeutic targets in arthritis treatment |
| Q36622407 | Mitogen activated protein kinase inhibitors: where are we now and where are we going? |
| Q41847267 | Mitogen-activated protein kinase kinase kinase 1 protects against nickel-induced acute lung injury. |
| Q47422829 | Piperlongumine inhibits the proliferation, migration and invasion of fibroblast-like synoviocytes from patients with rheumatoid arthritis |
| Q35751545 | Selective involvement of ERK and JNK mitogen-activated protein kinases in early rheumatoid arthritis (1987 ACR criteria compared to 2010 ACR/EULAR criteria): a prospective study aimed at identification of diagnostic and prognostic biomarkers as well |
| Q33557663 | Signal pathways JNK and NF-kappaB, identified by global gene expression profiling, are involved in regulation of TNFalpha-induced mPGES-1 and COX-2 expression in gingival fibroblasts |
| Q35553538 | Signal transduction networks in rheumatoid arthritis. |
| Q34348280 | Structural basis for the selective inhibition of JNK1 by the scaffolding protein JIP1 and SP600125. |
| Q37623872 | Synovial fibroblasts infected with Salmonella enterica serovar Typhimurium mediate osteoclast differentiation and activation |
| Q38461672 | Synthesis and SAR of 2-Phenoxypyridines as novel c-Jun N-terminal kinase inhibitors |
| Q38465442 | Synthesis and SAR of 4-(pyrazol-3-yl)-pyridines as novel c-jun N-terminal kinase inhibitors |
| Q38451579 | Synthesis and SAR of novel isoxazoles as potent c-jun N-terminal kinase (JNK) inhibitors |
| Q27655443 | Synthesis and SAR of piperazine amides as novel c-jun N-terminal kinase (JNK) inhibitors |
| Q35158010 | Targeting JNK for therapeutic benefit: from junk to gold? |
| Q37502685 | Targeting innate immunity protein kinase signalling in inflammation |
| Q26785513 | The Role of Poly(ADP-ribose) Polymerase-1 in Rheumatoid Arthritis |
| Q30500831 | The c-jun kinase/stress-activated pathway: regulation, function and role in human disease |
| Q34779788 | Therapeutic modulation of inflammatory gene transcription by kinase inhibitors |
| Q35787657 | Therapeutic modulation of signal transduction pathways. |
| Q35214545 | Therapy for chronic obstructive pulmonary disease in the 21st century. |
| Q36889171 | Tumor necrosis factor-induced toxic liver injury results from JNK2-dependent activation of caspase-8 and the mitochondrial death pathway |
| Q24812465 | Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo |
| Q37694304 | Update on Targets of Biologic Therapies for Rheumatoid Arthritis. |
| Q36286056 | c-Jun N-Terminal Kinase in Inflammation and Rheumatic Diseases. |
| Q26998420 | c-Jun N-Terminal Kinases Mediate a Wide Range of Targets in the Metastatic Cascade |
| Q36956736 | c-Jun N-terminal kinases as potential therapeutic targets |
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