Modelling large areas of demyelination in the rat reveals the potential and possible limitations of transplanted glial cells for remyelination in the CNS.

scientific article published in April 2002

Modelling large areas of demyelination in the rat reveals the potential and possible limitations of transplanted glial cells for remyelination in the CNS. is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/GLIA.10067
P698PubMed publication ID11948809

P50authorDivya M ChariQ63696595
P2093author name stringW F Blakemore
A J Crang
J M Gilson
P2860cites workSchwann cells transplanted into normal and X-irradiated adult white matter do not migrate extensively and show poor long-term survival.Q50510445
Suppression of remyelination in the CNS by X-irradiationQ67337430
Extensive Oligodendrocyte Remyelination following Injection of Cultured Central Nervous System Cells into Demyelinating Lesions in Adult Central Nervous SystemQ68363978
The effect of the number of oligodendrocytes transplanted into X-irradiated, glial-free lesions on the extent of oligodendrocyte remyelinationQ69793575
Delayed infarction of spinal cord white matter following x-irradiationQ70405673
Transplanted glial cells migrate over a greater distance and remyelinate demyelinated lesions more rapidly than endogenous remyelinating cellsQ74016311
Areas of demyelination do not attract significant numbers of schwann cells transplanted into normal white matterQ74166426
Efficient recolonisation of progenitor-depleted areas of the CNS by adult oligodendrocyte progenitor cellsQ77707852
Transplantation of clonal neural precursor cells derived from adult human brain establishes functional peripheral myelin in the rat spinal cordQ28143116
Co-localization of NG2 proteoglycan and PDGF alpha-receptor on O2A progenitor cells in the developing rat brainQ28565002
A common neural progenitor for the CNS and PNS.Q34067171
Remyelination and restoration of axonal function by glial cell transplantationQ34120819
Transplantation of glial cells enhances action potential conduction of amyelinated spinal cord axons in the myelin-deficient ratQ34885824
Distinctive patterns of PDGF-A, FGF-2, IGF-I, and TGF-beta1 gene expression during remyelination of experimentally-induced spinal cord demyelination.Q40792686
Embryonic stem cell-derived glial precursors: a source of myelinating transplantsQ40938819
Local recruitment of remyelinating cells in the repair of demyelination in the central nervous systemQ41066214
Reconstruction of the glial environment of a photochemically induced lesion in the rat spinal cord by transplantation of mixed glial cellsQ41177376
Transplanted CG4 cells (an oligodendrocyte progenitor cell line) survive, migrate, and contribute to repair of areas of demyelination in X-irradiated and damaged spinal cord but not in normal spinal cordQ41233816
Type 1 astrocytes fail to inhibit Schwann cell remyelination of CNS axons in the absence of cells of the O-2A lineage.Q41648460
Transplantation of Normal and Genetically Engineered Glia into Areas of DemyelinationQ41705480
Cooperation between PDGF and FGF converts slowly dividing O-2Aadult progenitor cells to rapidly dividing cells with characteristics of O-2Aperinatal progenitor cellsQ43108447
Depletion of endogenous oligodendrocyte progenitors rather than increased availability of survival factors is a likely explanation for enhanced survival of transplanted oligodendrocyte progenitors in X-irradiated compared to normal CNS.Q48921303
P433issue2
P921main subjectneurogliaQ177105
P304page(s)155-168
P577publication date2002-04-01
P1433published inGliaQ15716658
P1476titleModelling large areas of demyelination in the rat reveals the potential and possible limitations of transplanted glial cells for remyelination in the CNS
P478volume38

Reverse relations

cites work (P2860)
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