Antitumor activity and safety of combination therapy with the Toll-like receptor 9 agonist IMO-2055, erlotinib, and bevacizumab in advanced or metastatic non-small cell lung cancer patients who have progressed following chemotherapy

scientific article published on 27 April 2014

Antitumor activity and safety of combination therapy with the Toll-like receptor 9 agonist IMO-2055, erlotinib, and bevacizumab in advanced or metastatic non-small cell lung cancer patients who have progressed following chemotherapy is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1021772197
P356DOI10.1007/S00262-014-1547-6
P698PubMed publication ID24770667

P2093author name stringDonald A Richards
Thomas E Boyd
David A Smith
Alain C Mita
John J Nemunaitis
Alice S Bexon
Guillaume de La Bourdonnaye
Paul Conkling
David Wages
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TLR9 agonist acts by different mechanisms synergizing with bevacizumab in sensitive and cetuximab-resistant colon cancer xenograftsQ35894601
Phase II study of bevacizumab and erlotinib in the treatment of advanced hepatocellular carcinoma patients with sorafenib-refractory diseaseQ36357360
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Phase I/II trial evaluating the anti-vascular endothelial growth factor monoclonal antibody bevacizumab in combination with the HER-1/epidermal growth factor receptor tyrosine kinase inhibitor erlotinib for patients with recurrent non-small-cell lunQ45309210
Phase Ib trial of the Toll-like receptor 9 agonist IMO-2055 in combination with 5-fluorouracil, cisplatin, and cetuximab as first-line palliative treatment in patients with recurrent/metastatic squamous cell carcinoma of the head and neckQ45732639
Novel toll-like receptor 9 agonist induces epidermal growth factor receptor (EGFR) inhibition and synergistic antitumor activity with EGFR inhibitors.Q46905280
Phase II study of efficacy and safety of bevacizumab in combination with chemotherapy or erlotinib compared with chemotherapy alone for treatment of recurrent or refractory non small-cell lung cancerQ46972019
P433issue8
P407language of work or nameEnglishQ1860
P921main subjecterlotinibQ418369
toll-like receptorQ408004
bevacizumabQ413299
P304page(s)787-796
P577publication date2014-04-27
P1433published inCancer Immunology, ImmunotherapyQ5031409
P1476titleAntitumor activity and safety of combination therapy with the Toll-like receptor 9 agonist IMO-2055, erlotinib, and bevacizumab in advanced or metastatic non-small cell lung cancer patients who have progressed following chemotherapy
P478volume63

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