Up-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells. A paracrine effect mediated by prostaglandin E2 and nuclear factor-kappa B.

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Up-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells. A paracrine effect mediated by prostaglandin E2 and nuclear factor-kappa B. is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M201347200
P698PubMed publication ID12006564
P5875ResearchGate publication ID11363843

P50authorKunihiro OkamuraQ114082577
Mitsutoshi TamuraQ114292054
Serdar BulunQ22277212
Hironobu SasanoQ61126397
P2093author name stringKaren Ferrer
Siby Sebastian
Bilgin Gurates
Sijun Yang
P2860cites workAlterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2Q70787131
Immunohistochemical localisation of cyclooxygenase in the human uterusQ71603499
Regulation of cyclooxygenase-2 by interferon gamma and transforming growth factor alpha in normal human epidermal keratinocytes and squamous carcinoma cells. Role of mitogen-activated protein kinasesQ73041199
Critical role of C/EBPdelta and C/EBPbeta factors in the stimulation of the cyclooxygenase-2 gene transcription by interleukin-1beta in articular chondrocytesQ73199262
Cyclooxygenase 2 expression is increased in the stroma of colon carcinomas from IL-10(-/-) miceQ73386832
Distribution of cyclooxygenase-2 in eutopic and ectopic endometrium in endometriosis and adenomyosisQ73562927
Human cyclooxygenase-2 cDNAQ24293134
Multiple nuclear factors interact with the immunoglobulin enhancer sequencesQ24296245
Cyclooxygenase regulates angiogenesis induced by colon cancer cellsQ24336248
A conserved AU sequence from the 3' untranslated region of GM-CSF mRNA mediates selective mRNA degradationQ27860824
Characterization of the human gene (PTGS2) encoding prostaglandin-endoperoxide synthase 2Q28253346
Transcriptional regulation of human prostaglandin-endoperoxide synthase-2 gene by lipopolysaccharide and phorbol ester in vascular endothelial cells. Involvement of both nuclear factor for interleukin-6 expression site and cAMP response elementQ28289531
Prostaglandin endoperoxide H synthases (cyclooxygenases)-1 and -2Q28299729
AU-rich elements: characterization and importance in mRNA degradationQ29547896
TNF- and cancer therapy-induced apoptosis: potentiation by inhibition of NF-kappaBQ29614706
NF-kappaB antiapoptosis: induction of TRAF1 and TRAF2 and c-IAP1 and c-IAP2 to suppress caspase-8 activationQ29618715
The p50 subunit of NF-kappa B associates with the NF-IL6 transcription factorQ31076639
Temporal and pharmacological division of fibroblast cyclooxygenase expression into transcriptional and translational phasesQ33841391
Prostaglandin E(2) regulates the level and stability of cyclooxygenase-2 mRNA through activation of p38 mitogen-activated protein kinase in interleukin-1 beta-treated human synovial fibroblasts.Q33952839
The biochemistry of 3'-end cleavage and polyadenylation of messenger RNA precursors.Q34243656
Cyclooxygenase-2 expression in human colon cancer cells increases metastatic potentialQ36085224
Functional and physical associations between NF-kappa B and C/EBP family members: a Rel domain-bZIP interactionQ36689762
Structure of the human cyclo-oxygenase-2 geneQ36725123
Characterization of the genomic structure, chromosomal location and promoter of human prostaglandin H synthase-2 geneQ36738705
Characterization of the promoter of human prostaglandin H synthase-1 geneQ36775816
Transcriptional roles of nuclear factor kappa B and nuclear factor-interleukin-6 in the tumor necrosis factor alpha-dependent induction of cyclooxygenase-2 in MC3T3-E1 cellsQ38287673
Involvement of nuclear factor kappa B in the regulation of cyclooxygenase-2 expression by interleukin-1 in rheumatoid synoviocytesQ38348859
Hypoxia induces cyclooxygenase-2 via the NF-kappaB p65 transcription factor in human vascular endothelial cellsQ38349479
Is cyclooxygenase-2 the alpha and the omega in cancer?Q40365138
Expression of cyclooxygenase 2 by prostaglandin E(2) in human endometrial adenocarcinoma cell line HEC-1B.Q40859830
Prostaglandin E(2) upregulates cyclooxygenase-2 expression in lipopolysaccharide-stimulated RAW 264.7 macrophagesQ40873094
Requirement of NF-kappaB activation to suppress p53-independent apoptosis induced by oncogenic Ras.Q41074033
Ending the message is not so simpleQ41245633
Inhibition of cyclooxygenase: a novel approach to cancer preventionQ41626074
Up-regulation of cyclooxygenase-2 by product-prostaglandin E2.Q42547341
v-src induces prostaglandin synthase 2 gene expression by activation of the c-Jun N-terminal kinase and the c-Jun transcription factorQ42820538
Effect of endogenous and exogenous prostaglandin E(2) on interleukin-1 beta-induced cyclooxygenase-2 expression in human airway smooth-muscle cellsQ43511440
Prostaglandin E2 increases growth and motility of colorectal carcinoma cellsQ43559615
Expression, localization, and signaling of PGE(2) and EP2/EP4 receptors in human nonpregnant endometrium across the menstrual cycleQ43732477
Immunohistochemical localization of prostaglandin H synthase in the female reproductive tract and endometriosisQ44122756
Multiple signal transduction pathways through two prostaglandin E receptor EP3 subtype isoforms expressed in human uterusQ47811024
P433issue29
P407language of work or nameEnglishQ1860
P921main subjectprostaglandin E2Q416554
P304page(s)26208-26216
P577publication date2002-05-10
P1433published inJournal of Biological ChemistryQ867727
P1476titleUp-regulation of cyclooxygenase-2 expression and prostaglandin synthesis in endometrial stromal cells by malignant endometrial epithelial cells. A paracrine effect mediated by prostaglandin E2 and nuclear factor-kappa B.
P478volume277

Reverse relations

cites work (P2860)
Q585652726-Shogaol reduces progression of experimental endometriosis and regulation of VGEF and inhibition of COX-2 and PGE2-mediated inflammatory responses
Q46424625Aspirin use and endometrial cancer risk and survival.
Q33801778Aspirin, NSAID, and acetaminophen use and the risk of endometrial cancer
Q46567254Expression of cyclooxygenase-2 (COX-2), receptors for estrogen (ER), and progesterone (PR), p53, ki67, and neu protein in endometrial cancer.
Q40330937Hypoxia induced by benign intestinal epithelial cells is associated with cyclooxygenase-2 expression in stromal cells through AP-1-dependent pathway.
Q44512882IL-1beta-dependent activation of NF-kappaB mediates PGE2 release via the expression of cyclooxygenase-2 and microsomal prostaglandin E synthase.
Q28173990Increased PGE2 levels in nonmalignant mucosa adjacent to squamous cell carcinoma of the head and neck
Q36509755Inflammatory status influences aromatase and steroid receptor expression in endometriosis.
Q35107985Lipoxin A₄ prevents the progression of de novo and established endometriosis in a mouse model by attenuating prostaglandin E₂ production and estrogen signaling
Q36767568Local and systemic factors and implantation: what is the evidence?
Q38590189MAP kinases and the inflammatory signaling cascade as targets for the treatment of endometriosis?
Q37274380Modulation of signaling pathways in prostate cancer by green tea polyphenols
Q45165258Nimesulide, a COX-2 inhibitor, does not reduce lesion size or number in a nude mouse model of endometriosis.
Q38323790Nitric oxide upregulates the cyclooxygenase-2 expression through the cAMP-response element in its promoter in several cancer cell lines
Q50695828Nuclear factor-kappa B is constitutively activated in peritoneal endometriosis.
Q53201080Pre-treatment diagnosis of endometrial cancer through a combination of CA125 and multiplication of neutrophil and monocyte.
Q37761617Prostaglandin E2: the master of endometriosis?
Q89736259Regulation of Inflammation Pathways and Inflammasome by Sex Steroid Hormones in Endometriosis
Q34095034Role of progesterone in endometrial cancer
Q36172739Synergistic effects of RXR alpha and PPAR gamma ligands to inhibit growth in human colon cancer cells--phosphorylated RXR alpha is a critical target for colon cancer management
Q37424846Targeting receptor tyrosine kinases for chemoprevention by green tea catechin, EGCG
Q45414539The involvement of nuclear factor-kappa B in cyclooxygenase-2 overexpression in murine colon cancer cells transduced with herpes simplex virus thymidine kinase gene
Q42991846The relationship of COX-2 expression with estrogen receptor, progesterone receptor and prognostic parameters in endometrial carcinomas
Q37601781The role of microRNAs in endometriosis and associated reproductive conditions

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