| P2093 | author name string | Xin Lu | |
| | Qi Cao | |
| | Robert R Henry | |
| | Michael J Quon | |
| | Simeon I Taylor | |
| | Liwu Li | |
| | Theodore P Ciaraldi | |
| | Dongming Zhang | |
| | Zhekang Ying | |
| | Helen Sun | |
| | Soohyun Park Kim | |
| | Xiao-Jian Sun | |
| P2860 | cites work | Inflammation and insulin resistance | Q22241893 |
| | Inflammatory pathways and insulin action | Q75220950 |
| | A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance | Q77652485 |
| | Endothelin-1 modulates insulin signaling through phosphatidylinositol 3-kinase pathway in vascular smooth muscle cells | Q77759133 |
| | Glucose toxicity is responsible for the development of impaired regulation of endogenous glucose production and hepatic glucokinase in Zucker diabetic fatty rats | Q80175273 |
| | Toll-like receptor cross-hyporesponsiveness is functional in interleukin-1-receptor-associated kinase-1 (IRAK-1)-deficient macrophages: differential role played by IRAK-1 in regulation of tumour necrosis factor and interleukin-10 production | Q81063045 |
| | Obesity, Inflammation, and Insulin Resistance | Q22250939 |
| | Essential role of insulin receptor substrate-2 in insulin stimulation of Glut4 translocation and glucose uptake in brown adipocytes | Q22254159 |
| | Tyr(612) and Tyr(632) in human insulin receptor substrate-1 are important for full activation of insulin-stimulated phosphatidylinositol 3-kinase activity and translocation of GLUT4 in adipose cells | Q24291346 |
| | Pleiotropic insulin signals are engaged by multisite phosphorylation of IRS-1 | Q24304774 |
| | Role of IRS-2 in insulin and cytokine signalling | Q24337494 |
| | Interleukin-1 (IL-1) receptor-associated kinase leads to activation of TAK1 by inducing TAB2 translocation in the IL-1 signaling pathway | Q24550984 |
| | Toll-like receptor signalling | Q24570126 |
| | IL-1-induced NFkappa B and c-Jun N-terminal kinase (JNK) activation diverge at IL-1 receptor-associated kinase (IRAK) | Q24635274 |
| | Mechanism of ER Stress and Inflammation for Hepatic Insulin Resistance in Obesity | Q26785412 |
| | Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein | Q28116980 |
| | Inflamm-aging. An evolutionary perspective on immunosenescence | Q28141817 |
| | Reversal of obesity- and diet-induced insulin resistance with salicylates or targeted disruption of Ikkbeta | Q28188643 |
| | Endoplasmic reticulum stress and atherosclerosis | Q28279152 |
| | Regulation of insulin receptor substrate 1 pleckstrin homology domain by protein kinase C: role of serine 24 phosphorylation | Q28581138 |
| | Physiological role of Akt in insulin-stimulated translocation of GLUT4 in transfected rat adipose cells | Q28586458 |
| | Critical nodes in signalling pathways: insights into insulin action | Q29614735 |
| | Protection from obesity-induced insulin resistance in mice lacking TNF-alpha function | Q29616104 |
| | Local and systemic insulin resistance resulting from hepatic activation of IKK-beta and NF-kappaB | Q29619314 |
| | IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-alpha- and obesity-induced insulin resistance | Q29619774 |
| | Phosphorylation of Ser24 in the pleckstrin homology domain of insulin receptor substrate-1 by Mouse Pelle-like kinase/interleukin-1 receptor-associated kinase: cross-talk between inflammatory signaling and insulin signaling that may contribute [...] | Q31162696 |
| | Insulin resistance, lipotoxicity, type 2 diabetes and atherosclerosis: the missing links. The Claude Bernard Lecture 2009 | Q33880303 |
| | Modulation of insulin receptor, insulin receptor substrate-1, and phosphatidylinositol 3-kinase in liver and muscle of dexamethasone-treated rats | Q33906333 |
| | Micrococci and peptidoglycan activate TLR2-->MyD88-->IRAK-->TRAF-->NIK-->IKK-->NF-kappaB signal transduction pathway that induces transcription of interleukin-8 | Q34006791 |
| | X chromosome-linked IRAK-1 polymorphism is a strong predictor of multiple organ failure and mortality postinjury. | Q34158003 |
| | Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice. | Q34196736 |
| | Banting Lecture. Insulin action, diabetogenes, and the cause of type II diabetes | Q34330770 |
| | Adrenergic pathway activation enhances brown adipose tissue metabolism: a [¹⁸F]FDG PET/CT study in mice | Q34375039 |
| | Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors | Q34501763 |
| | Coordinated regulation of nutrient and inflammatory responses by STAMP2 is essential for metabolic homeostasis | Q34625793 |
| | Current approaches for assessing insulin sensitivity and resistance in vivo: advantages, limitations, and appropriate usage | Q34706104 |
| | The effects of salsalate on glycemic control in patients with type 2 diabetes: a randomized trial | Q35111527 |
| | Salsalate improves glycemia and inflammatory parameters in obese young adults | Q35580779 |
| | Regulation of insulin receptor substrate-1 in liver and muscle of animal models of insulin resistance | Q35608446 |
| | QUICKI is a useful and accurate index of insulin sensitivity | Q43881330 |
| | Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle | Q43990155 |
| | Fatty acid infusion selectively impairs insulin action on Akt1 and protein kinase C lambda /zeta but not on glycogen synthase kinase-3. | Q44049215 |
| | QUICKI is a useful index of insulin sensitivity in subjects with hypertension | Q44391891 |
| | Insulin-stimulated protein kinase C lambda/zeta activity is reduced in skeletal muscle of humans with obesity and type 2 diabetes: reversal with weight reduction | Q44527038 |
| | Chronic exposure to interleukin-6 causes hepatic insulin resistance in mice | Q44631827 |
| | A genetic and physiological study of impaired glucose homeostasis control in C57BL/6J mice | Q45281560 |
| | Free fatty acid impairment of nitric oxide production in endothelial cells is mediated by IKKbeta | Q45282771 |
| | Insulin resistance in spontaneously hypertensive rats is associated with endothelial dysfunction characterized by imbalance between NO and ET-1 production. | Q46406338 |
| | Assessing the predictive accuracy of QUICKI as a surrogate index for insulin sensitivity using a calibration model | Q46570511 |
| | Dehydroepiandrosterone mimics acute actions of insulin to stimulate production of both nitric oxide and endothelin 1 via distinct phosphatidylinositol 3-kinase- and mitogen-activated protein kinase-dependent pathways in vascular endothelium. | Q46864603 |
| | Signal transduction pathways activated by the IL-1 receptor family: ancient signaling machinery in mammals, insects, and plants | Q47759209 |
| | Impaired regulation of hepatic glucose production in mice lacking the forkhead transcription factor Foxo1 in liver | Q48386175 |
| | Mammalian facilitative glucose transporters: evidence for similar substrate recognition sites in functionally monomeric proteins | Q48418596 |
| | Kinetics of GLUT1 and GLUT4 glucose transporters expressed in Xenopus oocytes. | Q49146856 |
| | Transgenic mice with muscle-specific insulin resistance develop increased adiposity, impaired glucose tolerance, and dyslipidemia. | Q51581344 |
| | Pathogenesis of Hypoglycemia in Insulinoma Patients: Suppression of Hepatic Glucose Production by Insulin | Q51655108 |
| | Repeatable noninvasive measurement of mouse myocardial glucose uptake with 18F-FDG: evaluation of tracer kinetics in a type 1 diabetes model. | Q53098477 |
| | The union of vascular and metabolic actions of insulin in sickness and in health. | Q53859168 |
| | IL-1 receptor-associated kinase modulates host responsiveness to endotoxin. | Q54023203 |
| | Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis | Q73178283 |
| | Molecular mechanisms of insulin resistance and the role of the adipocyte | Q73318407 |
| | Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction | Q74191142 |
| | Obesity: An overview of possible role(s) of gut hormones, lipid sensing and gut microbiota | Q35873170 |
| | Metabolic stress signaling mediated by mixed-lineage kinases | Q36002831 |
| | The association between innate immunity gene (IRAK1) and C-reactive protein in the Diabetes Heart Study | Q36015656 |
| | The pathogenesis of insulin resistance: integrating signaling pathways and substrate flux | Q36430696 |
| | Reciprocal relationships between insulin resistance and endothelial dysfunction: molecular and pathophysiological mechanisms. | Q36450952 |
| | Protein kinase C-zeta phosphorylates insulin receptor substrate-1, -3, and -4 but not -2: isoform specific determinants of specificity in insulin signaling. | Q36578889 |
| | Reciprocal relationships between abnormal metabolic parameters and endothelial dysfunction. | Q36706086 |
| | Splanchnic regulation of glucose production | Q36804677 |
| | Cardiovascular actions of insulin | Q36831533 |
| | Toll-like receptor 2 mediates high-fat diet-induced impairment of vasodilator actions of insulin | Q36836199 |
| | Dehydroepiandrosterone stimulates phosphorylation of FoxO1 in vascular endothelial cells via phosphatidylinositol 3-kinase- and protein kinase A-dependent signaling pathways to regulate ET-1 synthesis and secretion | Q36944784 |
| | An integrated view of insulin resistance and endothelial dysfunction | Q37035654 |
| | Tissue-specific insulin resistance in mice with mutations in the insulin receptor, IRS-1, and IRS-2. | Q37174878 |
| | Signalling adaptors used by Toll-like receptors: an update. | Q37244997 |
| | IRS-1 activates phosphatidylinositol 3'-kinase by associating with src homology 2 domains of p85 | Q37276745 |
| | Diet-induced obese mice develop peripheral, but not central, resistance to leptin | Q37362925 |
| | Phosphorylation of IRS proteins Yin-Yang regulation of insulin signaling | Q37403974 |
| | TIR-containing adaptors in Toll-like receptor signalling | Q37407517 |
| | Metformin and insulin suppress hepatic gluconeogenesis through phosphorylation of CREB binding protein | Q37417220 |
| | Sympathetic nervous activation in obesity and the metabolic syndrome--causes, consequences and therapeutic implications. | Q37695713 |
| | Muscle insulin resistance: assault by lipids, cytokines and local macrophages | Q37760003 |
| | Inflammatory signaling in skeletal muscle insulin resistance: green signal for nutritional intervention? | Q37788937 |
| | Obesity-associated insulin resistance in skeletal muscle: role of lipid accumulation and physical inactivity. | Q37845219 |
| | Gut microbiota interactions with obesity, insulin resistance and type 2 diabetes: did gut microbiote co-evolve with insulin resistance? | Q37890823 |
| | Adaptive immunity in obesity and insulin resistance | Q38030832 |
| | Interleukin-6 depletion selectively improves hepatic insulin action in obesity | Q38327645 |
| | Inflammaging and Anti-Inflammaging: The Role of Cytokines in Extreme Longevity | Q38666958 |
| | Molecular mechanism underlying the suppression of lipid oxidation during endotoxemia | Q39471490 |
| | PKC-theta knockout mice are protected from fat-induced insulin resistance | Q39989111 |
| | PKCdelta-mediated IRS-1 Ser24 phosphorylation negatively regulates IRS-1 function | Q40232546 |
| | Nicotinamide nucleotide transhydrogenase: a key role in insulin secretion | Q40332664 |
| | Interleukin-1 receptor-associated kinase-1 plays an essential role for Toll-like receptor (TLR)7- and TLR9-mediated interferon-{alpha} induction | Q40446857 |
| | In vivo regulation of lipolysis in humans. | Q40746005 |
| | Insulin stimulation of phosphatidylinositol 3-kinase activity and association with insulin receptor substrate 1 in liver and muscle of the intact rat. | Q41851321 |
| | Vascular inflammation, insulin resistance, and reduced nitric oxide production precede the onset of peripheral insulin resistance. | Q41862776 |
| | Standard operating procedures for describing and performing metabolic tests of glucose homeostasis in mice | Q42427575 |
| | Increased glucose uptake promotes oxidative stress and PKC-delta activation in adipocytes of obese, insulin-resistant mice | Q42444551 |
| | Insulin stimulates increased catalytic activity of phosphoinositide-dependent kinase-1 by a phosphorylation-dependent mechanism | Q42510563 |
| | Salsalate may have broad utility in the prevention and treatment of vascular disorders and the metabolic syndrome | Q43192053 |
| P433 | issue | 29 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | interleukins | Q194908 |
| | glycobiology | Q899224 |
| P304 | page(s) | 12339-12350 | |
| P577 | publication date | 2017-06-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Deletion of interleukin 1 receptor-associated kinase 1 (Irak1) improves glucose tolerance primarily by increasing insulin sensitivity in skeletal muscle | |
| P478 | volume | 292 | |