Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component

scientific article published in June 2002

Antidiabetic effects of Panax ginseng berry extract and the identification of an effective component is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.2337/DIABETES.51.6.1851
P698PubMed publication ID12031973

P2093author name stringChun-Su Yuan
Kenneth S Polonsky
Jing-Tian Xie
Liu Zhang
Anoja S Attele
Lucy Dey
Yun-Ping Zhou
Ji An Wu
William Pugh
Paul A Rue
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectPanax ginsengQ182881
P304page(s)1851-1858
P577publication date2002-06-01
P1433published inDiabetesQ895262
P1476titleAntidiabetic effects of Panax ginseng berry extract and the identification of an effective component
P478volume51

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cites work (P2860)
Q36782002A mixture of the aqueous extract of Garcinia cambogia, soy peptide and L: -carnitine reduces the accumulation of visceral fat mass in rats rendered obese by a high fat diet
Q42816014A quantified ginseng (Panax ginseng C.A. Meyer) extract influences lipid acquisition and increases adiponectin expression in 3T3-L1 cells.
Q37250329A systematic review of the efficacy and safety of herbal medicines used in the treatment of obesity
Q58595391AKT-targeted anti-inflammatory activity of calyx ethanolic extract
Q36122678Accumulation characteristics and correlation analysis of five ginsenosides with different cultivation ages from different regions
Q92572878Acute and genetic toxicity of GS-E3D, a new pectin lyase-modified red ginseng extract
Q41203375Aguamiel concentrate from Agave salmiana and its extracted saponins attenuated obesity and hepatic steatosis and increased Akkermansia muciniphila in C57BL6 mice
Q38699935Alcohol extract of North American ginseng (Panax quinquefolius) reduces fatty liver, dyslipidemia, and other complications of metabolic syndrome in a mouse model
Q37136042American ginseng berry juice intake reduces blood glucose and body weight in ob/ob mice
Q40660633American ginseng modulates pancreatic beta cell activities
Q34803578American ginseng stimulates insulin production and prevents apoptosis through regulation of uncoupling protein-2 in cultured beta cells
Q89619869Anti-Cancer Effects of Panax ginseng Berry Polysaccharides via Activation of Immune-Related Cells
Q34173158Anti-Hyperglycemic Properties of Crude Extract and Triterpenes from Poria cocos
Q44303049Anti-diabetic and anti-obese effects of ginseng berry extract: comparison between intraperitoneal and oral administrations
Q35732682Anti-diabetic effect of Wen-pi-tang-Hab-Wu-ling-san extract in streptozotocin-induced diabetic rats
Q51352693Anti-diabetic effect of a traditional Chinese medicine formula.
Q38121039Anti-diabetic potential of Panax notoginseng saponins (PNS): a review
Q37283794Anti-obesity effects of black ginseng extract in high fat diet-fed mice
Q36916161Antidiabetic Activity of Polysaccharides from Tuberous Root of Liriope spicata var. prolifera in KKAy Mice
Q35843855Antidiabetic Activity of Ruellia tuberosa L., Role of α-Amylase Inhibitor: In Silico, In Vitro, and In Vivo Approaches
Q37543166Antidiabetic Effects of Carassius auratus Complex Formula in High Fat Diet Combined Streptozotocin-Induced Diabetic Mice
Q40795846Antidiabetic activity of Helicteres angustifolia root
Q46173759Antidiabetic and Antidyslipidemic Activities of the Aqueous Extract of Cochlospermum planchonii Leaves in Streptozotocin-Induced Diabetic Rats
Q90011363Antidiabetic and antihyperlipidemic effect of Duvalia corderoyi in rats with streptozotocin-induced diabetes
Q37720696Antidiabetic and gastric emptying inhibitory effect of herbal Melia azedarach leaf extract in rodent models of diabetes type 2 mellitus
Q36723068Antidiabetic effect and mode of action of cytopiloyne
Q50355680Antidiabetic phytoconstituents and their mode of action on metabolic pathways
Q47580171Antidiabetic, antioxidant, and TNF-α lowering properties of extract of the traditionally used plant Ixeris gracilis in alloxan-induced diabetic mice
Q35297479Antihyperglycemic effect of ganoderma lucidum polysaccharides on streptozotocin-induced diabetic mice
Q38470005Antiobesity activity of fermented Angelicae gigantis by high fat diet-induced obese rats
Q35757149Antiobesity and Antihyperglycemic Effects of Ginsenoside Rb1 in Rats
Q39909615Antioxidant protection by American ginseng in pancreatic beta-cells
Q91906834Autophagy and its regulation by ginseng components
Q37585283Bioconversion of ginsenosides in the american ginseng ( xī yáng shēn) extraction residue by fermentation with lingzhi ( líng zhī, ganoderma lucidum)
Q46196882Biomass and content of ginsenosides and polyacetylenes in American ginseng roots can be increased without affecting the profile of bioactive compounds
Q33699475Blood glucose lowering activity of aloe based composition, UP780, in alloxan induced insulin dependent mouse diabetes model
Q58032898Botanical, Pharmacological, Phytochemical, and Toxicological Aspects of the Antidiabetic Plant Bidens pilosa L
Q37848089Chemical and pharmacological studies of saponins with a focus on American ginseng
Q41757385Chemical differentiation and quality evaluation of commercial Asian and American ginsengs based on a UHPLC-QTOF/MS/MS metabolomics approach
Q34893867Classification of ginseng berry (Panax ginseng C.A. MEYER) extract using 1H NMR spectroscopy and its inhibition of lipid accumulation in 3 T3-L1 cells
Q34517159Commonly Used Dietary Supplements on Coagulation Function during Surgery
Q92988829Comparative Analysis of Panax ginseng Berries from Seven Cultivars Using UPLC-QTOF/MS and NMR-Based Metabolic Profiling
Q40857553Comparison of Ginsenoside Contents in Different Parts of Korean Ginseng (Panax ginseng C.A. Meyer).
Q39101221Compound K modulates fatty acid-induced lipid droplet formation and expression of proteins involved in lipid metabolism in hepatocytes
Q48174268Comprehensive Profiling and Quantification of Ginsenosides in the Root, Stem, Leaf, and Berry of Panax ginseng by UPLC-QTOF/MS.
Q37587581Corydalis edulis Maxim. Promotes Insulin Secretion via the Activation of Protein Kinase Cs (PKCs) in Mice and Pancreatic β Cells.
Q37368051Current evaluation of the millennium phytomedicine- ginseng (II): Collected chemical entities, modern pharmacology, and clinical applications emanated from traditional Chinese medicine.
Q78419821Current literature in diabetes
Q36730854Cycloartane Triterpenes from the Aerial Parts of Actaea racemosa.
Q44931280Decreasing, null and increasing effects of eight popular types of ginseng on acute postprandial glycemic indices in healthy humans: the role of ginsenosides
Q38942500Determination of ginsenosides in Asian and American ginsengs by liquid chromatography-quadrupole/time-of-flight MS: assessing variations based on morphological characteristics.
Q37191153EFFECTS OF GINSENG AND ITS FOUR PURIFED GINSENOSIDES (Rb2, Re, Rg1, Rd) ON HUMAN PANCREATIC ISLET β CELL IN VITRO.
Q37291981Effect of Chinese Herbal Medicine Jinlida Granule in Treatment of Patients with Impaired Glucose Tolerance
Q99239652Effect of Pleurotus fossulatus Aqueous Extract on Biochemical Properties of Liver and Kidney in Streptozotocin-Induced Diabetic Rat
Q50561764Effect of Sancaijiangtang on plasma nitric oxide and endothelin-1 levels in patients with type 2 diabetes mellitus and vascular dementia: a single-blind randomized controlled trial.
Q35968042Effect of ethanolic extract of Cryptolepis sanguinolenta stem on in vivo and in vitro glucose absorption and transport: Mechanism of its antidiabetic activity
Q42811385Effect of ginsenosides Rg3 and Re on glucose transport in mature 3T3-L1 adipocytes
Q46929462Effective antidiabetic and antioxidant fractions of Otostegia persica extract and their constituents
Q44135507Effects of American ginseng berry extract on blood glucose levels in ob/ob mice
Q90194205Effects of Harvest Time on Phytochemical Constituents and Biological Activities of Panax ginseng Berry Extracts
Q37084421Effects of Korean ginseng berry extract (GB0710) on penile erection: evidence from in vitro and in vivo studies
Q53118944Effects of Korean ginseng berry extract on sexual function in men with erectile dysfunction: a multicenter, placebo-controlled, double-blind clinical study.
Q34297946Effects of Korean white ginseng extracts on obesity in high-fat diet-induced obese mice
Q34768771Effects of Oral Administration of Moringa oleifera Lam on Glucose Tolerance in Goto-Kakizaki and Wistar Rats
Q47383539Effects of energy drinks on the cardiovascular system
Q55436200Effects of fermented ginseng root and ginseng berry on obesity and lipid metabolism in mice fed a high-fat diet.
Q34458593Effects of ginsenoside Re on LPS-induced inflammatory mediators in BV2 microglial cells
Q41172067Effects of ginsenosides Re and Rg3 on intracellular redox state and cell proliferation in C6 glioma cells
Q35014337Effects of pectin lyase-modified red ginseng extracts in high-fat diet-fed obese mice
Q49389012Efficacy and safety of Panax ginseng berry extract on glycemic control: A 12-wk randomized, double-blind, and placebo-controlled clinical trial
Q33585792Efficacy and safety of ginsam, a vinegar extract from Panax ginseng, in type 2 diabetic patients: Results of a double-blind, placebo-controlled study.
Q21203643Ethnomedicines used in Trinidad and Tobago for urinary problems and diabetes mellitus
Q34302707Evaluation of the genotoxicity of ginseng leaf extract UG0712.
Q90744684Factors influencing cultivated ginseng (Panax ginseng C. A. Meyer) bioactive compounds
Q53309290Fermentation of protopanaxadiol type ginsenosides (PD) with probiotic Bifidobacterium lactis and Lactobacillus rhamnosus.
Q46861129Five batches representative of Ontario-grown American ginseng root produce comparable reductions of postprandial glycemia in healthy individuals
Q46393814Free radical-scavenging activity of Korean red ginseng for erectile dysfunction in non-insulin-dependent diabetes mellitus rats
Q87359317Functional analysis of 3-hydroxy-3-methylglutaryl coenzyme a reductase encoding genes in triterpene saponin-producing ginseng
Q37959577Functional food and diabetes: a natural way in diabetes prevention?
Q36846255Ginseng Berry Extract Attenuates Dextran Sodium Sulfate-Induced Acute and Chronic Colitis.
Q36458704Ginseng Berry Extract Prevents Atherogenesis via Anti-Inflammatory Action by Upregulating Phase II Gene Expression
Q64107641Ginseng Berry Extract Rich in Phenolic Compounds Attenuates Oxidative Stress but not Cardiac Remodeling post Myocardial Infarction
Q38700575Ginseng Metabolites on Cancer Chemoprevention: An Angiogenesis Link?
Q36457798Ginseng and Its Active Components Ginsenosides Inhibit Adipogenesis in 3T3-L1 Cells by Regulating MMP-2 and MMP-9.
Q36209148Ginseng and diabetes
Q38110276Ginseng and diabetes: the evidences from in vitro, animal and human studies
Q35043848Ginseng and ginsenoside Re do not improve β-cell function or insulin sensitivity in overweight and obese subjects with impaired glucose tolerance or diabetes
Q33849975Ginseng essence, a medicinal and edible herbal formulation, ameliorates carbon tetrachloride-induced oxidative stress and liver injury in rats.
Q42600073Ginseng leaf-stem: bioactive constituents and pharmacological functions
Q37309905Ginseng on hyperglycemia: effects and mechanisms
Q47231285Ginseng panaxoside Rb1 reduces body weight in diet-induced obese mice
Q35333767Ginseng total saponin improves podocyte hyperpermeability induced by high glucose and advanced glycosylation endproducts
Q55457341Ginsenoside Ameliorates Cognitive Dysfunction in Type 2 Diabetic Goto-Kakizaki Rats.
Q42085077Ginsenoside Rb1 increases insulin sensitivity by activating AMP-activated protein kinase in male rats
Q37732975Ginsenoside Rb1 increases insulin sensitivity through suppressing 11β-hydroxysteroid dehydrogenase type I.
Q38748086Ginsenoside Rb1 preconditioning enhances eNOS expression and attenuates myocardial ischemia/reperfusion injury in diabetic rats
Q33755348Ginsenoside Rb2 Alleviates Hepatic Lipid Accumulation by Restoring Autophagy via Induction of Sirt1 and Activation of AMPK.
Q64086666Ginsenoside Rb2 Alleviates Obesity by Activation of Brown Fat and Induction of Browning of White Fat
Q54284369Ginsenoside Re Promotes Nerve Regeneration by Facilitating the Proliferation, Differentiation and Migration of Schwann Cells via the ERK- and JNK-Dependent Pathway in Rat Model of Sciatic Nerve Crush Injury.
Q36185988Ginsenoside Re rapidly reverses insulin resistance in muscles of high-fat diet fed rats
Q33643299Ginsenoside Re reduces insulin resistance through inhibition of c-Jun NH2-terminal kinase and nuclear factor-kappaB.
Q35811907Ginsenoside Re: Its chemistry, metabolism and pharmacokinetics
Q37925017Ginsenoside Re: pharmacological effects on cardiovascular system
Q42941644Ginsenoside Rg3 Suppresses Palmitate-Induced Apoptosis in MIN6N8 Pancreatic beta-Cells
Q41919317Ginsenoside profiles and related gene expression during foliation in Panax ginseng Meyer
Q56558872Ginsenoside-Rg1 enhances angiogenesis and ameliorates ventricular remodeling in a rat model of myocardial infarction
Q46874796Ginsenoside-free molecules from steam-dried ginseng berry promote ethanol metabolism: an alternative choice for an alcohol hangover
Q39919391Ginsenosides Rb1 and Rg1 suppress triglyceride accumulation in 3T3-L1 adipocytes and enhance beta-cell insulin secretion and viability in Min6 cells via PKA-dependent pathways
Q34776476Ginsenosides are novel naturally-occurring aryl hydrocarbon receptor ligands
Q28293006Ginsenosides chemistry, biosynthesis, analysis, and potential health effects
Q24630142Ginsenosides from American ginseng: chemical and pharmacological diversity
Q35675150Glycosyl glycerides from hydroponic Panax ginseng inhibited NO production in lipopolysaccharide-stimulated RAW264.7 cells
Q36861324HPLC-based metabolic profiling and quality control of leaves of different Panax species
Q36801780Herbal therapies for type 2 diabetes mellitus: chemistry, biology, and potential application of selected plants and compounds
Q38519504Hibiscus Extract Inhibits the Lipid Droplet Accumulation and Adipogenic Transcription Factors Expression of 3T3-L1 Preadipocytes
Q39578160Hypoglycemic activity of C-glycosyl flavonoid from Enicostemma hyssopifolium
Q35829954Hypoglycemic and Hypolipidemic Effects of Ethanolic Extract of Mirabilis jalapa L. Root on Normal and Diabetic Mice
Q90147043Identification of a novel triterpene saponin from Panax ginseng seeds, pseudoginsenoside RT8, and its antiinflammatory activity
Q36176980Identification of natural products with neuronal and metabolic benefits through autophagy induction
Q35917912Improvement of oral availability of ginseng fruit saponins by a proliposome delivery system containing sodium deoxycholate
Q50515051In vitro and in vivo antihyperglycemic effect of 2 amadori rearrangement compounds, arginyl-fructose and arginyl-fructosyl-glucose.
Q36328819In vitro antioxidant and, α-glucosidase inhibitory activities and comprehensive metabolite profiling of methanol extract and its fractions from Clinacanthus nutans
Q36861083Increase in Insulin Secretion Induced by Panax ginseng Berry Extracts Contributes to the Amelioration of Hyperglycemia in Streptozotocininduced Diabetic Mice
Q36855511Influence of fluoride on streptozotocin induced diabetic nephrotoxicity in mice: protective role of Asian ginseng (Panax ginseng) & banaba (Lagerstroemia speciosa) on mitochondrial oxidative stress
Q36232791Insulin combined with Chinese medicine improves glycemic outcome through multiple pathways in patients with type 2 diabetes mellitus
Q50738247Korean red ginseng rootlets decrease acute postprandial glycemia: results from sequential preparation- and dose-finding studies.
Q51368612Linking biological activity with herbal constituents by systems biology-based approaches: effects of Panax ginseng in type 2 diabetic Goto-Kakizaki rats.
Q47260792Multiple Effects of Ginseng Berry Polysaccharides: Plasma Cholesterol Level Reduction and Enteric Neoplasm Prevention
Q37727562Natural products for type II diabetes treatment
Q37899052Natural products in anti-obesity therapy.
Q37801882Naturally Occurring Triterpenoid Saponins
Q44319057Neuroactive and other free amino acids in seed and young plants of Panax ginseng
Q92588815Neuroprotective Effects of Red Ginseng Saponins in Scopolamine-Treated Rats and Activity Screening Based on Pharmacokinetics
Q59008335New Steroidal Erythrityl Triesters from the Heat Processed Roots of Panax ginseng
Q37021286Non-traditional therapies for diabetes: fact or fiction
Q44699045Null and opposing effects of Asian ginseng (Panax ginseng C.A. Meyer) on acute glycemia: results of two acute dose escalation studies
Q33570445Orally administrated ascorbic acid suppresses neuronal damage and modifies expression of SVCT2 and GLUT1 in the brain of diabetic rats with cerebral ischemia-reperfusion
Q42822868Pachymic acid stimulates glucose uptake through enhanced GLUT4 expression and translocation
Q41997397Panax ginseng Leaf Extracts Exert Anti-Obesity Effects in High-Fat Diet-Induced Obese Rats
Q38303715Panax ginseng increases hypoxia-induced down-regulated cellular response related genes in human neuroblastoma cells, SK-N-MC.
Q33361454Pharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir
Q35947889Pharmacokinetics of a multicomponent herbal preparation in healthy Chinese and African volunteers.
Q38205765Phytotherapy in diabetes: Review on potential mechanistic perspectives
Q51320880Polysaccharides from Laminaria japonica show hypoglycemic and hypolipidemic activities in mice with experimentally induced diabetes.
Q42741212Porosity changes and retention of ginsenosides in North American ginseng root using different dehydration processes
Q51075139Preventive effect of American ginseng against premature ovarian failure in a rat model.
Q93042687Production of ginsenoside aglycone (protopanaxatriol) and male sterility of transgenic tobacco co-overexpressing three Panax ginseng genes: PgDDS, CYP716A47, and CYP716A53v2
Q42906730Protective effect of Clerodendron glandulosum extract against experimentally induced metabolic syndrome in rats.
Q38752226Protective effect of ginsenoside Re on acute gastric mucosal lesion induced by compound 48/80.
Q39680383Protective effect of salidroside from Rhodiolae Radix on diabetes-induced oxidative stress in mice.
Q42722181Protective effects of ginsenosides against Bisphenol A-induced cytotoxicity in 15P-1 Sertoli cells via extracellular signal-regulated kinase 1/2 signalling and antioxidant mechanisms
Q34659350Protopanaxatriol, a novel PPARγ antagonist from Panax ginseng, alleviates steatosis in mice
Q46045222Quantitative analysis of ginsenosides Rb1, Rg1, and Re in American ginseng berry and flower samples by ELISA using monoclonal antibodies
Q26823373Radio-protective role of antioxidant agents
Q38524167Recent progress in natural products as DPP-4 inhibitors.
Q34173212Red ginseng extract facilitates the early differentiation of human embryonic stem cells into mesendoderm lineage
Q37964521Red ginseng for type 2 diabetes mellitus: a systematic review of randomized controlled trials
Q47669914Relative Bioavailability of Silybin A and Silybin B From 2 Multiconstituent Dietary Supplement Formulations Containing Milk Thistle Extract: A Single-dose Study.
Q37348604Rg3 Improves Mitochondrial Function and the Expression of Key Genes Involved in Mitochondrial Biogenesis in C2C12 Myotubes
Q37155968Roles of chlorogenic Acid on regulating glucose and lipids metabolism: a review
Q46217869Saponins isolated from the root of Panax notoginseng showed significant anti-diabetic effects in KK-Ay mice
Q48200654Sarsasapogenin-AA13 ameliorates Aβ-induced cognitive deficits via improving neuroglial capacity on Aβ clearance and antiinflammation.
Q47955202State of Panax ginseng Research: A Global Analysis.
Q90447043Stereoselective and Simultaneous Analysis of Ginsenosides from Ginseng Berry Extract in Rat Plasma by UPLC-MS/MS: Application to a Pharmacokinetic Study of Ginseng Berry Extract
Q33833589Study of antihyperglycaemic activity of medicinal plant extracts in alloxan induced diabetic rats
Q36534179Supplementation of Korean Red Ginseng improves behavior deviations in animal models of autism
Q43970675Suppression of mitochondrial oxidative phosphorylation and TCA enzymes in discrete brain regions of mice exposed to high fluoride: amelioration by Panax ginseng (Ginseng) and Lagerstroemia speciosa (Banaba) extracts
Q37798050Targeting metabolic syndrome: Candidate natural agents
Q28548552The Efficacy and Safety of Chinese Herbal Medicine Jinlida as Add-On Medication in Type 2 Diabetes Patients Ineffectively Managed by Metformin Monotherapy: A Double-Blind, Randomized, Placebo-Controlled, Multicenter Trial
Q26766298The Efficacy of Ginseng-Related Therapies in Type 2 Diabetes Mellitus: An Updated Systematic Review and Meta-analysis
Q37628368The Root Extract of Pueraria lobata and Its Main Compound, Puerarin, Prevent Obesity by Increasing the Energy Metabolism in Skeletal Muscle
Q44571547The anti-obesity effects of the dietary combination of fermented red ginseng with levan in high fat diet mouse model
Q43078135The antidiabetic effects of a dry powder of dietary vegetable and fruit mixtures in diabetic db/db mice.
Q37617790The metabolic syndrome: definition, global impact, and pathophysiology
Q36853578The rs1142345 in TPMT Affects the Therapeutic Effect of Traditional Hypoglycemic Herbs in Prediabetes
Q43263522The study of ginsenoside on PPARgamma expression of mononuclear macrophage in type 2 diabetes
Q27004043Therapeutic phytogenic compounds for obesity and diabetes
Q37943827Therapeutic potential of ginseng in the management of cardiovascular disorders
Q24657961Traditional chinese medicine in treatment of metabolic syndrome
Q39562298Treatment of diabetes using traditional Chinese medicine: past, present and future
Q58692356UPLC-QTOF/MS-Based Metabolomics Applied for the Quality Evaluation of Four Processed Products
Q90216471Ubiquitin-Fold Modifier-1 Participates in the Diabetic Inflammatory Response by Regulating NF-κB p65 Nuclear Translocation and the Ubiquitination and Degradation of IκBα
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