Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition

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Sepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1046/J.1471-4159.2002.00814.X
P698PubMed publication ID12067232
P5875ResearchGate publication ID11307842

P2093author name stringJohn X Wilson
Robert R Hammond
Feng Wu
Jasminka Korcok
Karel Tyml
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NADPH-diaphorase activity in activated astrocytes represents inducible nitric oxide synthase.Q36675667
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Regulation of nitric oxide synthase activity in cultured human endothelial cells: effect of antioxidantsQ41249362
Indicators of glial activation and brain oxidative stress after intraventricular infusion of endotoxin.Q42459029
The cytotoxicity of chronic neuroinflammation upon basal forebrain cholinergic neurons of rats can be attenuated by glutamatergic antagonism or cyclooxygenase-2 inhibitionQ42494371
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Endotoxin depletes ascorbate in the guinea pig heart. Protective effects of vitamins C and E against oxidative stressQ46306666
Impaired phosphatidylcholine biosynthesis and ascorbic acid depletion in lung during lipopolysaccharide-induced endotoxaemia in guinea pigs.Q46488698
Peroxynitrite mediated damage and lowered superoxide tolerance in primary cortical glial cultures after induction of the inducible isoform of NOS.Q48105656
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Systemic administration of lipopolysaccharide induces release of nitric oxide and glutamate and c-fos expression in the nucleus tractus solitarii of ratsQ48207415
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Effect of nitric oxide synthase induction on the expression of mitochondrial respiratory chain enzyme subunits in mixed cortical and astroglial cell culturesQ48303462
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Inducible nitric oxide synthase expression is selectively induced in astrocytes isolated from adult human brainQ48337097
In vivo nitric oxide detection in the septic rat brain by electron paramagnetic resonanceQ48419828
Glucose inhibits cellular ascorbic acid uptake by fibroblasts in vitroQ49285590
Xanthine oxidase activity and free radical generation in patients with sepsis syndrome.Q51561514
Ascorbyl radical formation in patients with sepsis: effect of ascorbate loading.Q51581411
Sodium-ascorbate cotransport controls intracellular ascorbate concentration in primary astrocyte cultures expressing the SVCT2 transporter.Q52072562
Reciprocal regulation of nitric oxide and glutamate in the nucleus tractus solitarii of rats.Q54547296
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectsepsisQ183134
astrocyteQ502961
P1104number of pages9
P304page(s)185-193
P577publication date2002-04-01
P1433published inJournal of NeurochemistryQ6295643
P1476titleSepsis inhibits reduction of dehydroascorbic acid and accumulation of ascorbate in astroglial cultures: intracellular ascorbate depletion increases nitric oxide synthase induction and glutamate uptake inhibition
P478volume81

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cites work (P2860)
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Q44362038Ascorbate inhibits iNOS expression and preserves vasoconstrictor responsiveness in skeletal muscle of septic mice
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Q34293902Endotoxin increases ascorbate recycling and concentration in mouse liver
Q40462883Enhancement of glutamate uptake mediates the neuroprotection exerted by activating group II or III metabotropic glutamate receptors on astrocytes.
Q33830681L-ascorbate attenuates the endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation and NF-κB translocation in cortical neurons/glia Cocultures
Q28392580Mechanisms of long-term cognitive dysfunction of sepsis: from blood-borne leukocytes to glial cells
Q30480840Microglial cells in astroglial cultures: a cautionary note
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Q35140259Progress in clinical neurosciences: sepsis-associated encephalopathy: evolving concepts
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Q40319470Small ubiquitin-like modifier (SUMO) modification of natively unfolded proteins tau and alpha-synuclein
Q34831003The physiological role of dehydroascorbic acid
Q89606276The role of astrocytes in oxidative stress of central nervous system: A mixed blessing

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