Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis

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Functional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis is …
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scholarly articleQ13442814

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P356DOI10.1046/J.1528-1157.43.S.5.14.X
P698PubMed publication ID12121291

P50authorStephanie BurrowsQ118868262
Maria Grazia De SimoniQ42857263
Annamaria VezzaniQ66943699
Carlo PeregoQ93176534
P2093author name stringCristina Richichi
Teresa Ravizza
Marisa Aliprandi
Daniela Moneta
P2860cites workModification of seizure activity by electrical stimulation. II. Motor seizureQ28236678
Kainic acid induced expression of interleukin-1 receptor antagonist mRNA in the rat brainQ28572894
Self-sustaining limbic status epilepticus induced by 'continuous' hippocampal stimulation: electrographic and behavioral characteristicsQ30460098
Powerful anticonvulsant action of IL-1 receptor antagonist on intracerebral injection and astrocytic overexpression in miceQ35314740
Inhibition of the p44/42 MAP kinase pathway protects hippocampal neurons in a cell-culture model of seizure activityQ36327960
Inflammatory cytokines within the central nervous system: sources, function, and mechanism of actionQ36347725
Functions and mechanisms of interleukin 1 in the brainQ36983479
Gene expression and function of interleukin 1, interleukin 6 and tumor necrosis factor in the brain.Q40610100
Cytokines in neuronal cell typesQ40903075
Interleukin-1beta does not increase synaptic inhibition in hippocampal CA3 pyramidal and dentate gyrus granule cells of the rat in vitroQ48594046
Inhibition of NMDA receptor-mediated synaptic transmission in the rat dentate gyrus in vitro by IL-1 betaQ48659789
Effects of kainic acid on messenger RNA levels of IL-1 beta, IL-6, TNF alpha and LIF in the rat brainQ48737439
Interleukin-1 beta inhibits long-term potentiation in the CA3 region of mouse hippocampal slicesQ48952312
Interleukin 1 beta inhibits synaptic strength and long-term potentiation in the rat CA1 hippocampus.Q52060326
P407language of work or nameEnglishQ1860
P921main subjectinflammationQ101991
P304page(s)30-35
P577publication date2002-01-01
P1433published inEpilepsiaQ5382969
P1476titleFunctional role of inflammatory cytokines and antiinflammatory molecules in seizures and epileptogenesis
P478volume43 Suppl 5

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cites work (P2860)
Q52347510A Cohort Study Comparing Women with Autism Spectrum Disorder with and without Generalized Joint Hypermobility.
Q37300227A novel non-transcriptional pathway mediates the proconvulsive effects of interleukin-1beta
Q36467289A postnatal peak in microglial development in the mouse hippocampus is correlated with heightened sensitivity to seizure triggers
Q62868539Abnormalities of cortical thickness in postictal psychosis
Q43254552Accidental induced seizures in three cynomologus macaques following administration of ceftriaxone dissolved in 1% lidocaine diluent
Q28584136Activation of NADPH oxidase and extracellular superoxide production in seizure-induced hippocampal damage
Q91938747Advances in the Potential Biomarkers of Epilepsy
Q39424230Alteration of plasma cytokines in patients with active epilepsy
Q47735914Altered MT1 and MT2 melatonin receptors expression in the hippocampus of pilocarpine-induced epileptic rats.
Q92176298Amygdaloid complex anatomopathological findings in animal models of status epilepticus
Q41922342Analysis of plasma multiplex cytokines and increased level of IL-10 and IL-1Ra cytokines in febrile seizures
Q37340703Anti-Inflammatory Small Molecules To Treat Seizures and Epilepsy: From Bench to Bedside
Q36103318Anticonvulsant effects of iridoid glycosides fraction purified from Feretia apodanthera Del. (Rubiaceae) in experimental mice models of generalized tonic-clonic seizures.
Q37403091Antiepileptic Effect of Uncaria rhynchophylla and Rhynchophylline Involved in the Initiation of c-Jun N-Terminal Kinase Phosphorylation of MAPK Signal Pathways in Acute Seizures of Kainic Acid-Treated Rats
Q36661383Apoptosis through Death Receptors in Temporal Lobe Epilepsy-Associated Hippocampal Sclerosis
Q50767481Association of Interleukin-1 Gene Cluster and Interleukin-1 Receptor Polymorphisms With Febrile Seizures.
Q47913485Autoradiographic analysis of rat brain kinin B1 and B2 receptors: normal distribution and alterations induced by epilepsy
Q47098901Beneficial Effects of Silibinin Against Kainic Acid-induced Neurotoxicity in the Hippocampus in vivo
Q33735865Bi-directionally protective communication between neurons and astrocytes under ischemia
Q38058374Blood-brain barrier dysfunction-induced inflammatory signaling in brain pathology and epileptogenesis
Q40510318Brain Inflammation and Seizures
Q35200145Brain tumor and seizures: pathophysiology and its implications for treatment revisited
Q38114855Causes of CNS inflammation and potential targets for anticonvulsants
Q37090266Cerebroprotective functions of HO-2.
Q30493038Comorbidity between epilepsy and depression: role of hippocampal interleukin-1beta
Q48244586Complex alterations in microglial M1/M2 markers during the development of epilepsy in two mouse models
Q36339709Correlation Between IL-10 and microRNA-187 Expression in Epileptic Rat Hippocampus and Patients with Temporal Lobe Epilepsy
Q27342573Critical Evaluation of P2X7 Receptor Antagonists in Selected Seizure Models
Q48517821Cytokine Polymorphism and HLA Genotyping in Patients with Temporal Lobe Epilepsy Related to Hippocampal Sclerosis
Q61463933Cytokine Receptors in the Brain
Q36542185Cytokines and brain excitability.
Q37173555Cytokines and brain injury: invited review.
Q47222317Differential response of hippocampal and prefrontal oscillations to systemic LPS application
Q48892545Distribution, characterization and clinical significance of microglia in glioneuronal tumours from patients with chronic intractable epilepsy
Q42104426Dynamic Change in Cells Expressing IL-1β in Rat Hippocampus after Status Epilepticus
Q36055590Effects of neuroinflammation on the regenerative capacity of brain stem cells
Q37242260Epilepsy, cognition, and neuropsychiatry (Epilepsy, Brain, and Mind, part 2)
Q37792844Epilepsy: recent advances.
Q38002125Epileptic encephalitis: the role of the innate and adaptive immune system
Q89572778Ex vivo model of epilepsy in organotypic slices-a new tool for drug screening
Q48228365Expression of adhesion factors induced by epileptiform activity in the endothelium of the isolated guinea pig brain in vitro
Q45180901Expressions of tumor necrosis factor alpha and microRNA-155 in immature rat model of status epilepticus and children with mesial temporal lobe epilepsy
Q37579506Febrile infection-related epilepsy syndrome treated with anakinra
Q37779665Functional, metabolic, and synaptic changes after seizures as potential targets for antiepileptic therapy.
Q48158817Glial activation links early-life seizures and long-term neurologic dysfunction: evidence using a small molecule inhibitor of proinflammatory cytokine upregulation
Q37102107HIV-1-infected and/or immune-activated macrophage-secreted TNF-alpha affects human fetal cortical neural progenitor cell proliferation and differentiation
Q52150313High serum levels of proinflammatory markers during epileptogenesis. Can omega-3 fatty acid administration reduce this process?
Q30497503Hippocampal FGF-2 and BDNF overexpression attenuates epileptogenesis-associated neuroinflammation and reduces spontaneous recurrent seizures.
Q36835195Hippocampal gene expression dysregulation of Klotho, nuclear factor kappa B and tumor necrosis factor in temporal lobe epilepsy patients
Q38460619IL-1β induction and IL-6 suppression are associated with aggravated neuronal damage in a lipopolysaccharide-pretreated kainic acid-induced rat pup seizure model
Q27022067Immune mechanisms in cerebral ischemic tolerance
Q37795443Immunological aspects of epilepsy.
Q49143369Increased Expression and Cellular Localization of P2X7R in Cortical Lesions of Patients With Focal Cortical Dysplasia
Q35014514Increased expression of the chemokines CXCL1 and MIP-1α by resident brain cells precedes neutrophil infiltration in the brain following prolonged soman-induced status epilepticus in rats
Q92023682Inflammation and "The Epileptic Heart"
Q41867461Inflammation and epilepsy
Q37254517Inflammation mediates varying effects in neurogenesis: relevance to the pathogenesis of brain injury and neurodegenerative disorders
Q44476509Inflammatory changes during epileptogenesis and spontaneous seizures in a mouse model of mesiotemporal lobe epilepsy.
Q40074599Inflammatory cytokine-induced changes in neural network activity measured by waveform analysis of high-content calcium imaging in murine cortical neurons.
Q35202804Inflammatory mechanisms associated with brain damage induced by kainic acid with special reference to the interleukin-1 system.
Q35951508Inhibition of toll-like receptor and cytokine signaling--a unifying theme in ischemic tolerance
Q48469394Interleukin-1β and microRNA-146a in an immature rat model and children with mesial temporal lobe epilepsy
Q30500480Interleukin-1β biosynthesis inhibition reduces acute seizures and drug resistant chronic epileptic activity in mice
Q35737149Interleukin-1β in Central Nervous System Injury and Repair.
Q41119536Interleukin-1β plasma levels are associated with depression in temporal lobe epilepsy
Q60977241Interleukin-6 bares a dark side in sudden unexpected death in epilepsy
Q48719793Interleukin-6 levels are increased in temporal lobe epilepsy but not in extra-temporal lobe epilepsy.
Q49721281Intrinsic Inflammation Is a Potential Anti-Epileptogenic Target in the Organotypic Hippocampal Slice Model.
Q59798783Is Mossy Fiber Sprouting a Potential Therapeutic Target for Epilepsy?
Q58449892Is omega-3 fatty acid deficiency a factor contributing to refractory seizures and SUDEP?
Q37047430Lack of association between TNF-α gene polymorphisms at position -308 A, -850T and risk of simple febrile convulsion in pediatric patients
Q30544940Maternal immune activation promotes hippocampal kindling epileptogenesis in mice
Q46574500Modulation of seizures and synaptic plasticity by adenosinergic receptors in an experimental model of temporal lobe epilepsy induced by pilocarpine in rats
Q92778048Molecular alterations of the TLR4-signaling cascade in canine epilepsy
Q55228929NADPH oxidases as potential pharmacological targets against increased seizure susceptibility after systemic inflammation.
Q35739474Naringin Attenuates Autophagic Stress and Neuroinflammation in Kainic Acid-Treated Hippocampus In Vivo
Q38115775Neural circuit mechanisms of post-traumatic epilepsy
Q97073856Neurobiology of coronaviruses: Potential relevance for COVID-19
Q91530192Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy
Q35574583Neuromodulatory role of endogenous interleukin-1β in acute seizures: possible contribution of cyclooxygenase-2
Q38139837New avenues for anti-epileptic drug discovery and development
Q36228613New facets of the neuropathology and molecular profile of human temporal lobe epilepsy
Q36823723New roles for interleukin-1 Beta in the mechanisms of epilepsy
Q33988508Omega-3 fatty acid supplementation in patients with chronic epilepsy: a randomized trial
Q33568656Optimization of multiplexed bead-based cytokine immunoassays for rat serum and brain tissue
Q37540412Pathogenesis of epilepsy: challenges in animal models
Q44494963Peripheral inflammatory activation after hippocampus irradiation in the rat.
Q35128609Peripherally restricted acute phase response to a viral mimic alters hippocampal gene expression
Q38262011Personalized medicine approaches in epilepsy
Q49049938Pilocarpine-induced epilepsy alters the expression and daily variation of the nuclear receptor RORα in the hippocampus of rats
Q37238455Platelet-activating factor receptor antagonism targets neuroinflammation in experimental epilepsy
Q36542199Postnatal inflammation increases seizure susceptibility in adult rats.
Q38263071Potential pharmacological strategies for the improved treatment of organophosphate-induced neurotoxicity.
Q37366817Protection of DFP-induced oxidative damage and neurodegeneration by antioxidants and NMDA receptor antagonist
Q36372950Protein expression profiling of inflammatory mediators in human temporal lobe epilepsy reveals co-activation of multiple chemokines and cytokines
Q48214403Resveratrol suppressed seizures by attenuating IL-1β, IL1-Ra, IL-6, and TNF-α in the hippocampus and cortex of kindled mice
Q41933030Role of cytokines during epileptogenesis and in the transition from the interictal to the ictal state in the epileptic mutant EL mouse
Q53478215Salivary Immunosuppressive Cytokines IL-10 and IL-13 Are Significantly Elevated in Oral Squamous Cell Carcinoma Patients.
Q38679789Silencing of P2X7R by RNA interference in the hippocampus can attenuate morphological and behavioral impact of pilocarpine-induced epilepsy
Q37295661Studies on brain volume, Alzheimer-related proteins and cytokines in mice with chronic overexpression of IL-1 receptor antagonist
Q55496766Tb II-I, a Fraction Isolated from Tityus bahiensis Scorpion Venom, Alters Cytokines': Level and Induces Seizures When Intrahippocampally Injected in Rats.
Q46173375Temporal profile of clinical signs and histopathologic changes in an F-344 rat model of kainic acid-induced mesial temporal lobe epilepsy
Q42252596Temporal profiles of age-dependent changes in cytokine mRNA expression and glial cell activation after status epilepticus in postnatal rat hippocampus.
Q40458487The effect of IL-1β on synaptophysin expression and electrophysiology of hippocampal neurons through the PI3K/Akt/mTOR signaling pathway in a rat model of mesial temporal lobe epilepsy.
Q38059289The epilepsies: complex challenges needing complex solutions
Q37328931The epileptic hypothesis: developmentally related arguments based on animal models
Q46496718The protective action of tumor necrosis factor alpha (TNF-alpha) on the hypersensitivity of pyramidal neurons in field CA1 in rat hippocampal slices induced by episodes of hypoxia
Q39373732The role of cytokines in seizures: interleukin (IL)-1β, IL-1Ra, IL-8, and IL-10.
Q36364424The role of inflammation in CNS injury and disease
Q51730982The role of the microRNA-146a/complement factor H/interleukin-1β-mediated inflammatory loop circuit in the perpetuate inflammation of chronic temporal lobe epilepsy.
Q33731012The therapeutic effect of the aqueous extract of boswellia serrata on the learning deficit in kindled rats
Q37941819Therapeutic potential of new antiinflammatory drugs
Q35746333Tropism and Induction of Cytokines in Human Embryonic-Stem Cells-Derived Neural Progenitors upon Inoculation with Highly- Pathogenic Avian H5N1 Influenza Virus
Q50357179Upregulation of insulin-like growth factor and interleukin 1β occurs in neurons but not in glial cells in the cochlear nucleus following cochlear ablation
Q41255642Using Postmortem hippocampi tissue can interfere with differential gene expression analysis of the epileptogenic process.
Q35834542Vascular endothelial growth factor (VEGF) in seizures: a double-edged sword
Q81153321[Neurogenesis in the adult brain: the demise of a dogma and the advent of new treatments]
Q48450823c-Jun N-terminal kinase activation responses induced by hippocampal kindling are mediated by reactive astrocytes.
Q57282966n-3 Docosapentaenoic acid-derived protectin D1 promotes resolution of neuroinflammation and arrests epileptogenesis

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