Elucidation of basic mechanistic and kinetic properties of influenza endonuclease using chemically synthesized RNAs

scientific article published in March 1996

Elucidation of basic mechanistic and kinetic properties of influenza endonuclease using chemically synthesized RNAs is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.271.13.7435
P698PubMed publication ID8631770
P5875ResearchGate publication ID14568331

P2093author name stringOlsen DB
Cole JL
Benseler F
Darke PL
Kuo LC
Stahlhut MW
Dempski RE
P2860cites workSolid phase synthesis of 5'-diphosphorylated oligoribonucleotides and their conversion to capped m7Gppp-oligoribonucleotides for use as primers for influenza A virus RNA polymerase in vitroQ40394934
Synthesis and applications of oligoribonucleotides with selected 2'-O-methylation using the 2'-O-[1-(2-fluorophenyl)-4-methoxypiperidin-4-yl] protecting groupQ40523443
Influenza A virus RNA polymerase subunit PB2 is the endonuclease which cleaves host cell mRNA and functions only as the trimeric enzymeQ41351807
Assay for influenza virus endonuclease using DNA polymerase extension of a specific cleavage productQ45771568
Cap-recognizing protein of influenza virusQ45794237
Characterization of cap structures.Q52454560
Energetics of Catalysis by Ribonucleases: Fate of the 2',3'-Cyclic Phosphodiester IntermediateQ57961275
Isolation of matrix protein M1 from influenza viruses by acid-dependent extraction with nonionic detergentQ67717924
Study of a hammerhead ribozyme containing 2'-modified adenosine residuesQ68000605
A unique cap(m7GpppXm)-dependent influenza virion endonuclease cleaves capped RNAs to generate the primers that initiate viral RNA transcriptionQ27865288
Molecular model of a eucaryotic transcription complex: functions and movements of influenza P proteins during capped RNA-primed transcriptionQ27865290
Biochemical studies on capped RNA primers identify a class of oligonucleotide inhibitors of the influenza virus RNA polymeraseQ35110210
Globin mRNAs are primers for the transcription of influenza viral RNA in vitroQ35994818
Role of two of the influenza virus core P proteins in recognizing cap 1 structures (m7GpppNm) on RNAs and in initiating viral RNA transcriptionQ36381848
Transfer of 5′-terminal cap of globin mRNA to influenza viral complementary RNA during transcription in vitroQ37326371
Studies of the interactions between Escherichia coli ribonuclease HI and its substrateQ38302743
Importance of exocyclic base functional groups of central core guanosines for hammerhead ribozyme activityQ38314474
P433issue13
P407language of work or nameEnglishQ1860
P304page(s)7435-7439
P577publication date1996-03-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleElucidation of basic mechanistic and kinetic properties of influenza endonuclease using chemically synthesized RNAs
P478volume271

Reverse relations

cites work (P2860)
Q39095563A sensitive, single-tube assay to measure the enzymatic activities of influenza RNA polymerase and other poly(A) polymerases: application to kinetic and inhibitor analysis
Q74489921Anti-influenza drugs and neuraminidase inhibitors
Q92719740Approaches for measuring the dynamics of RNA-protein interactions
Q73053424Approaches to high-volume screening assays of viral polymerases and related proteins
Q38642237Biochemical characterization of recombinant influenza A polymerase heterotrimer complex: Endonuclease activity and evaluation of inhibitors.
Q38344450Differential effect of modified capped RNA substrates on influenza virus transcription
Q35131625Efficient solid-phase synthesis of pppRNA by using product-specific labeling
Q45735419Influenza virus endoribonuclease
Q45744166RNA and DNA hydrolysis are catalyzed by the influenza virus endonuclease
Q53146842Solid-phase chemical synthesis of 5'-triphosphate DNA, RNA, and chemically modified oligonucleotides.
Q27486391Structure-function relationships among RNA-dependent RNA polymerases

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