Activation of spinal kainate receptors after inflammation: behavioral hyperalgesia and subunit gene expression

scientific article published in October 2002

Activation of spinal kainate receptors after inflammation: behavioral hyperalgesia and subunit gene expression is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0014-2999(02)02333-6
P698PubMed publication ID12359272

P2093author name stringWei Guo
Ke Ren
Shiping Zou
Michael Tal
P2860cites workCa2+ permeability of unedited and edited versions of the kainate selective glutamate receptor GluR6Q24563671
Q/R editing of the rat GluR5 and GluR6 kainate receptors in vivo and in vitro: evidence for independent developmental, pathological and cellular regulationQ28138013
The role of RNA editing of kainate receptors in synaptic plasticity and seizuresQ28200197
Editing status at the Q/R site of the GluR2 and GluR6 glutamate receptor subunits in the surgically excised hippocampus of patients with refractory epilepsyQ28278692
Non-NMDA glutamate receptors modulate capsaicin induced c-fos expression within trigeminal nucleus caudalisQ28343437
Rat GluR7 and a carboxy-terminal splice variant, GluR7b, are functional kainate receptor subunits with a low sensitivity to glutamateQ28578489
Cloning of a cDNA for a glutamate receptor subunit activated by kainate but not AMPAQ28579935
Primary structure and expression of the γ2 subunit of the glutamate receptor channel selective for kainateQ28587413
A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesiaQ29620385
Presynaptic kainate receptors regulate spinal sensory transmission.Q31813367
Glutamate receptor subunits GluR5 and KA-2 are coexpressed in rat trigeminal ganglion neurons.Q39421008
The effects of a non-competitive NMDA receptor antagonist, MK-801, on behavioral hyperalgesia and dorsal horn neuronal activity in rats with unilateral inflammationQ41102806
Dimensions and ion selectivity of recombinant AMPA and kainate receptor channels and their dependence on Q/R site residuesQ41161451
Effect of RNA editing and subunit co-assembly single-channel properties of recombinant kainate receptors.Q41208769
Cloning of a putative high-affinity kainate receptor expressed predominantly in hippocampal CA3 cellsQ41678682
Selective upregulation of the flip-flop splice variants of AMPA receptor subunits in the rat spinal cord after hindpaw inflammationQ43569925
Descending modulation of opioid-containing nociceptive neurons in rats with peripheral inflammation and hyperalgesiaQ44351761
Competitive inhibition by NBQX of kainate/AMPA receptor currents and excitatory synaptic potentials: importance of 6-nitro substitutionQ45122157
The KA-2 subunit of excitatory amino acid receptors shows widespread expression in brain and forms ion channels with distantly related subunits.Q45954696
Kainate GluR5 receptor subtype mediates the nociceptive response to formalin in the rat.Q47782247
Characterization of RNA editing of the glutamate-receptor subunits GluR5 and GluR6 in granule cells during cerebellar developmentQ48040793
A novel non-NMDA receptor antagonist shows selective displacement of low-affinity [3H]kainate bindingQ48232934
Kainate-receptor-mediated sensory synaptic transmission in mammalian spinal cordQ48297298
Region-specific expression of subunits of ionotropic glutamate receptors (AMPA-type, KA-type and NMDA receptors) in the rat spinal cord with special reference to nociceptionQ48316479
Decahydroisoquinolines: novel competitive AMPA/kainate antagonists with neuroprotective effects in global cerebral ischaemia.Q48331516
Chronic catheterization of the spinal subarachnoid spaceQ48344815
2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(F)quinoxaline: a neuroprotectant for cerebral ischemiaQ49105194
The intrathecal administration of excitatory amino acid receptor antagonists selectively attenuated carrageenan-induced behavioral hyperalgesia in rats.Q51685152
The non-N-methyl-D-aspartate receptor antagonists, GYKI 52466 and NBQX are anticonvulsant in two animal models of reflex epilepsyQ67650018
Glutamate receptor channels in rat DRG neurons: activation by kainate and quisqualate and blockade of desensitization by Con AQ68477606
Differential activation of spinal cord dynorphin and enkephalin neurons during hyperalgesia: evidence using cDNA hybridizationQ69922027
Selective block of recombinant glur6 receptors by NS-102, a novel non-NMDA receptor antagonistQ72426618
AMPA, KA and NMDA receptors are expressed in the rat DRG neuronesQ72553546
The differential expression of 16 NMDA and non-NMDA receptor subunits in the rat spinal cord and in periaqueductal grayQ72640800
The role of non-N-methyl-D-aspartate ionotropic glutamate receptors in the spinal transmission of nociception in normal animals and animals with carrageenan inflammationQ73029457
Parenterally administered kainic acid induces a persistent hyperalgesia in the mouse and ratQ73115205
Neuropharmacology of AMPA and kainate receptorsQ77668732
Actions of kainate and AMPA selective glutamate receptor ligands on nociceptive processing in the spinal cordQ77668758
The kainate receptor antagonist 2S,4R-4-methylglutamate attenuates mechanical allodynia and thermal hyperalgesia in a rat model of nerve injuryQ77770545
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)309-318
P577publication date2002-10-01
P1433published inEuropean Journal of PharmacologyQ1376712
P1476titleActivation of spinal kainate receptors after inflammation: behavioral hyperalgesia and subunit gene expression
P478volume452

Reverse relations

cites work (P2860)
Q28590073Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice
Q34810296Antinociceptive effects of MSVIII-19, a functional antagonist of the GluK1 kainate receptor
Q34389228Expression of KA1 kainate receptor subunit in the substantia gelatinosa of the trigeminal subnucleus caudalis in mice
Q37772543Glutamate receptor phosphorylation and trafficking in pain plasticity in spinal cord dorsal horn
Q45106035Group I metabotropic glutamate receptor NMDA receptor coupling and signaling cascade mediate spinal dorsal horn NMDA receptor 2B tyrosine phosphorylation associated with inflammatory hyperalgesia.
Q35564745High-Throughput Screen of GluK1 Receptor Identifies Selective Inhibitors with a Variety of Kinetic Profiles Using Fluorescence and Electrophysiology Assays.
Q41351924Intrathecal injection of GluR6 antisense oligodeoxynucleotides alleviates acute inflammatory pain of rectum in rats
Q37624494Ionotropic glutamate receptors in spinal nociceptive processing.
Q28511882Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit
Q41883858Molecular and pharmacological evidence for a facilitatory functional role of pre-synaptic GLUK2/3 kainate receptors on GABA release in rat trigeminal caudal nucleus
Q44963065Peripheral immune challenge with dsRNA enhances kainic acid-induced status epilepticus
Q41447707Peripheral nerve injury increases glutamate-evoked calcium mobilization in adult spinal cord neurons
Q35128609Peripherally restricted acute phase response to a viral mimic alters hippocampal gene expression
Q43247634Presynaptic regulation of the inhibitory transmission by GluR5-containing kainate receptors in spinal substantia gelatinosa
Q44434717SYM 2081, an agonist that desensitizes kainate receptors, attenuates capsaicin and inflammatory hyperalgesia

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