Alanine prevents the reduction of pyruvate kinase activity in brain cortex of rats subjected to chemically induced hyperphenylalaninemia.

scientific article published in September 2002

Alanine prevents the reduction of pyruvate kinase activity in brain cortex of rats subjected to chemically induced hyperphenylalaninemia. is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1036760037
P356DOI10.1023/A:1020351800882
P698PubMed publication ID12396106

P50authorAngela T.S. WyseQ64495879
Moacir WajnerQ89163680
Clóvis Milton Duval WannmacherQ114398581
P2093author name stringCarlos Severo Dutra-Filho
Luciane Rosa Feksa
Virginia Cielo Rech
Andrea Renata Cornelio
P2860cites workProtein measurement with the Folin phenol reagentQ20900776
Mitochondrial dysfunction is a primary event in glutamate neurotoxicityQ28290602
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Inhibition of human brain pyruvate kinase and hexokinase by phenylalanine and phenylpyruvate: possible relevance to phenylketonuric brain damageQ34230185
Biochemical and neuropsychological effects of elevated plasma phenylalanine in patients with treated phenylketonuria. A model for the study of phenylalanine and brain function in manQ34521900
Phenylalaninaemia. Differential diagnosisQ35151880
Intelligence and quality of dietary treatment in phenylketonuriaQ35624913
Adaptations of glucose and fatty acid metabolism during perinatal period and suckling-weaning transitionQ35969019
The effect of age upon the entry of some amino acids into the brain, and their incorporation into cerebral proteinQ36623451
Magnetic resonance imaging of the brain in phenylketonuriaQ36721838
White matter abnormalities in patients with treated hyperphenylalaninaemia: magnetic resonance relaxometry and proton spectroscopy findings.Q36745071
Comparative aspects of the brain growth spurtQ39707940
Development of enzymes of energy metabolism in the neonatal mammalian brain.Q40559762
Induction and properties of pyruvate kinase of the cerebral hemisphere of rats of various agesQ44090765
Anabolic effect of human growth hormone: management of inherited disorders of catabolic pathwaysQ46140933
Alanine prevents the decrease of Na+,K+-ATPase activity in experimental phenylketonuria.Q48111589
Cerebral alanine transport and alanine aminotransferase reaction: alanine as a source of neuronal glutamateQ48136075
Kinetics of phenylalanine transport at the human blood-brain barrier investigated in vivoQ48540291
Proton NMR observation of phenylalanine and an aromatic metabolite in the rabbit brain in vivoQ48961407
Effect of phenylalanine, p-chlorophenylalanine and alpha-methylphenylalanine on glucose uptake in vitro by the brain of young ratsQ48962541
Energy-metabolizing enzymes in brain regions of adult and aging ratsQ49149434
CONTROL OF GLUTAMATE METABOLISM. THE EFFECT OF PYRUVATEQ51256181
Decreased vigilance and neurotransmitter synthesis after discontinuation of dietary treatment for phenylketonuria in adolescents.Q52083180
Cerebral Glucose Metabolism Is Decreased in White Matter Changes in Patients with PhenylketonuriaQ53501253
Neuropsychological studies on adolescents with phenylketonuria returned to phenylalanine-restricted dietsQ68531822
Evidence for inhibition of exodus of small neutral amino acids from non-brain tissues in hyperphenylalaninaemic ratsQ69217298
Effect of age at loss of dietary control on intellectual performance and behavior of children with phenylketonuriaQ70006687
Effect of phenylalanine and alpha-methylphenylalanine on in vitro incorporation of 32P into cytoskeletal cerebral proteinsQ71953093
Neurological findings in early treated phenylketonuriaQ72345215
Effect of hyperphenylalaninemia chemically induced on in vitro incorporation of 32P into cytoskeletal proteins from cerebral cortex of developing ratsQ73123576
Phenylalanine inhibition of the phosphorylation of cytoskeletal proteins from cerebral cortex of young rats is prevented by alanineQ73883772
P433issue9
P921main subjectL-alanineQ218642
P304page(s)947-952
P577publication date2002-09-01
P1433published inNeurochemical ResearchQ15716728
P1476titleAlanine prevents the reduction of pyruvate kinase activity in brain cortex of rats subjected to chemically induced hyperphenylalaninemia
P478volume27

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cites work (P2860)
Q41930021Co-administration of creatine plus pyruvate prevents the effects of phenylalanine administration to female rats during pregnancy and lactation on enzymes activity of energy metabolism in cerebral cortex and hippocampus of the offspring
Q46158057Effects of β-alanine administration on selected parameters of oxidative stress and phosphoryltransfer network in cerebral cortex and cerebellum of rats
Q37868451Oxidative stress in phenylketonuria: what is the evidence?
Q52146802Phenylalanine induces oxidative stress and decreases the viability of rat astrocytes: possible relevance for the pathophysiology of neurodegeneration in phenylketonuria.
Q48611566Phenylalanine reduces synaptic density in mixed cortical cultures from mice
Q43285979Protective effect of antioxidants on cerebrum oxidative damage caused by arginine on pyruvate kinase activity.
Q48028295Pyruvate and creatine prevent oxidative stress and behavioral alterations caused by phenylalanine administration into hippocampus of rats
Q36753552Regulation of M2-type pyruvate kinase mediated by the high-affinity IgE receptors is required for mast cell degranulation

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