Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro

scientific article published in January 2002

Quinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0306-4522(02)00320-2
P8608Fatcat IDrelease_45tjaa3n6vhylgwdqkl2o6cvjy
P698PubMed publication ID12401338

P50authorRüdiger KöhlingQ38547408
P2093author name stringFox JE
Jefferys JG
Vreugdenhil M
Bikson M
Id Bihi R
P2860cites workThe novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunitsQ28138343
Suppression of epileptiform activity by high frequency sinusoidal fields in rat hippocampal slicesQ28349377
Hyperpolarizing shift by quinine in the steady-state inactivation curve of delayed rectifier-type potassium current in bullfrog sympathetic neurons.Q32025271
Phenytoin: mechanisms of its anticonvulsant actionQ38166737
The relationship between interictal and ictal paroxysms in an in vitro model of focal hippocampal epilepsyQ41337643
Established antiepileptic drugsQ41514494
Cell volume changes upon sodium pump inhibition in Helix aspersa neuronesQ41812494
Chemistry. Synthetic lessons from quinineQ43617715
4-Aminopyridine produces epileptiform activity in hippocampus and enhances synaptic excitation and inhibitionQ44430969
Effect of quinine on electroshock and pentylenetetrazol-induced seizures in miceQ44889781
Pre- and postsynaptic K+ and Ca2+ fluxes in area CA1 of the rat hippocampus in vitro: effects of Ni2+, TEA and 4-AP.Q45735738
Picrotoxin-induced epileptiform activity in hippocampus: role of endogenous versus synaptic factorsQ46372713
Effects of quinidine and quinine on the excitability of pyramidal neurons in guinea-pig hippocampal slicesQ46408742
Effects of TEA on hippocampal neuronsQ46939357
Electrical coupling underlies high-frequency oscillations in the hippocampus in vitroQ47908475
Inhibitory mechanisms terminating paroxysmal depolarization shifts in hippocampal neurons of ratsQ48088056
Nonsynaptic epileptogenesis in the mammalian hippocampus in vitro. II. Role of extracellular potassiumQ48313096
Effects of barium on stimulus-induced changes in [K+]o and field potentials in dentate gyrus and area CA1 of human epileptic hippocampusQ48421915
Effects of anticonvulsants on spontaneous epileptiform activity which develops in the absence of chemical synaptic transmission in hippocampal slicesQ48534543
CA3-driven hippocampal-entorhinal loop controls rather than sustains in vitro limbic seizuresQ48579668
Synchronized bursting of CA1 hippocampal pyramidal cells in the absence of synaptic transmissionQ48861160
Synchronous neural afterdischarges in rat hippocampal slices without active chemical synapsesQ48872147
Effects of phenytoin on normal activity and on penicillin-induced bursting in the guinea pig hippocampal sliceQ48930176
Potassium accumulation in interstitial space during epileptiform seizuresQ48931107
Effects of quinine on the excitability and voltage-dependent currents of isolated spiral ganglion neurons in culture.Q50505698
Modulation of burst frequency, duration, and amplitude in the zero-Ca(2+) model of epileptiform activity.Q51433514
A short period of hypoxia produces a rapid and transient rise in [K+]e in rat hippocampus in vivo which is inhibited by certain K+-channel blocking agentsQ51597331
Penicillin‐ and barium‐induced epileptiform bursting in hippocampal neurons: Actions on Ca++ and K+ potentialsQ52505746
D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.Q53989493
Dissociation of Synchronization and Excitability in Furosemide Blockade of Epileptiform ActivityQ56928654
Superfusion of verapamil on the cerebral cortex does not suppress epileptic discharges due to restricted diffusion (rats, in vivo)Q61848405
Effects of quinine on three different types of potassium currents in bullfrog sympathetic neuronsQ73198123
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)251-261
P577publication date2002-01-01
P1433published inNeuroscienceQ15708571
P1476titleQuinine suppresses extracellular potassium transients and ictal epileptiform activity without decreasing neuronal excitability in vitro
P478volume115

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cites work (P2860)
Q34632262Altered intrinsic properties of neuronal subtypes in malformed epileptogenic cortex
Q33979671Antiepileptic properties of Quinine: A systematic review
Q40488367Blocking of rat hippocampal Cx36 by quinine accelerates kindling epileptogenesis.
Q38646549Brain extracellular space, hyaluronan, and the prevention of epileptic seizures
Q47949685Current Study of the Mechanism of Action of the Potential Anti-Epileptic Agent Q808.
Q43978593Differential diagnosis and treatment of cramps
Q42105226Effects of glucose and glutamine concentration in the formulation of the artificial cerebrospinal fluid (ACSF).
Q48047202Extracellular Potassium and Seizures: Excitation, Inhibition and the Role of Ih.
Q51949095Learning-induced synchronization and plasticity of a developing neural network.
Q46725865Quinine, a blocker of neuronal cx36 channels, suppresses seizure activity in rat neocortex in vivo
Q37959793Role of gap junctions in epilepsy
Q28487997Thalamic modulation of cingulate seizure activity via the regulation of gap junctions in mice thalamocingulate slice
Q47891747The Effects of Quinine on Neurophysiological Properties of Dopaminergic Neurons.

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