Induction of apoptosis in human cancer cell lines by diospyrin, a plant-derived bisnaphthoquinonoid, and its synthetic derivatives

scientific article published in December 2002

Induction of apoptosis in human cancer cell lines by diospyrin, a plant-derived bisnaphthoquinonoid, and its synthetic derivatives is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/S0304-3835(02)00494-9
P698PubMed publication ID12406552

P2093author name stringMadhumita Roy
R K Bhattacharya
Banasri Hazra
Sutapa Chakrabarty
P2860cites workCaspases: enemies withinQ29547315
Caspases: killer proteasesQ29616315
A biochemical hallmark of apoptosis: internucleosomal degradation of the genomeQ35233718
The involvement of oncogenes and tumor suppressor genes in the control of apoptosisQ35370103
Bcl-2 and the regulation of programmed cell deathQ36233600
Molecular mechanisms of quinone cytotoxicityQ37367251
Metabolism and reactions of quinoid anticancer agentsQ39687822
A rapid and simple method for the isolation of apoptotic DNA fragments.Q40523306
Evidence that oxidative stress-induced apoptosis by menadione involves Fas-dependent and Fas-independent pathwaysQ40766109
Shikonin, an ingredient of Lithospermum erythrorhizon induced apoptosis in HL60 human premyelocytic leukemia cell lineQ40929513
Effect of concentration on the cytotoxic mechanism of doxorubicin--apoptosis and oxidative DNA damageQ41134680
The caspase family of cysteine proteasesQ41646592
Caspases: key mediators of apoptosisQ41760384
Caspase-3-mediated cleavage of the NF-kappa B subunit p65 at the NH2 terminus potentiates naphthoquinone analog-induced apoptosisQ43586943
beta-Lapachone-induced apoptosis in human prostate cancer cells: involvement of NQO1/xip3.Q43644682
Biological activity of diospyrin towards Ehrlich ascites carcinoma in Swiss A miceQ70685712
Acylshikonin analogues: synthesis and inhibition of DNA topoisomerase-IQ72117381
Diospyrin, a bisnaphthoquinone: a novel inhibitor of type I DNA topoisomerase of Leishmania donovaniQ77690971
The topoisomerase I inhibitors, camptothecin and beta-lapachone, induce apoptosis of human retinal pigment epithelial cellsQ77759960
Pharmacological Studies on the Effect of the Treatment of Swiss A Mice with Diospyrin, a Tumour-inhibitory Plant Product, and its Synthetic DerivativesQ104666887
P433issue1-2
P407language of work or nameEnglishQ1860
P921main subjectDiospyros montanaQ1227092
diospyrinQ27106425
P304page(s)85-93
P577publication date2002-12-01
P1433published inCancer LettersQ326372
P1476titleInduction of apoptosis in human cancer cell lines by diospyrin, a plant-derived bisnaphthoquinonoid, and its synthetic derivatives
P478volume188

Reverse relations

cites work (P2860)
Q38952634Acetylamine derivative of diospyrin, a plant-derived binaphthylquinonoid, inhibits human colon cancer growth in Nod-Scid mice.
Q24800170Apoptosis: targets in pancreatic cancer
Q105311210Cytotoxicity of Diospyrin and Its Derivatives in Relation to the Generation of Reactive Oxygen Species in Tumour Cells in vitroandin vivo
Q104847885Flavonol Glycosides in Two Diospyros Plants and Their Radical Scavenging Activity
Q39984492Increased cytotoxicity by the combination of radiation and diospyrin diethylether in fibrosarcoma in culture and in tumor
Q34009851Is nitric oxide decrease observed with naphthoquinones in LPS stimulated RAW 264.7 macrophages a beneficial property?
Q44636189Liquid chromatographic separation of derivatives of diospyrin, a bioactive bisnaphthoquinonoid plant-product, and analogous naphthyl compounds
Q40126752Radiosensitization by diospyrin diethylether in MCF-7 breast carcinoma cell line
Q37977473Reviews on 1,4-naphthoquinones from Diospyros L.
Q39932257Role of mitochondrial oxidative stress in the apoptosis induced by diospyrin diethylether in human breast carcinoma (MCF-7) cells
Q39175428Targeting heat shock proteins by phenethyl isothiocyanate results in cell-cycle arrest and apoptosis of human breast cancer cells

Search more.